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Onondaga County, NY Office Properties & Spaces for Sale

55 results
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Nedrow Office Building For Sale
$250,000
2,458 SF

Nedrow Office Building For Sale

7106 S Salina St, Nedrow, NY 13120

Office building in high-traffic area with parking and storage.

  • High‑traffic corner location at S. Salina St and Bailey St.
  • Ample off‑street parking with 8+ spaces.
  • 2458 sq ft of office space with two entrances.
  • Full walk‑out basement for storage.
  • Includes 3 separate offices, conference room, bathroom, and kitchenette.
Updated: Nov 10, 2025
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Syracuse Commercial/Industrial Building For Sale
$399,000
4,408 SF

Syracuse Commercial/Industrial Building For Sale

6730 Townline Rd, Syracuse, NY 13211

4,408 sq ft commercial/industrial building in a busy area.

  • 4,408 sq ft commercial/industrial building in a busy commercial‑industrial area.
  • Flexible layout with 6 front offices, shop area, cafeteria, and large rear meeting/conference area.
  • Shop area includes a large compressor and air lines.
  • Front and rear parking for approx. 12 vehicles with potential for additional parking.
  • Multi‑zone heating and air conditioning.
Updated: Nov 21, 2025
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Multi-Tenant Income Property in Syracuse
Pending
$1,350,000
19,650 SF

Multi-Tenant Income Property in Syracuse

Well-maintained multi-tenant property with income potential, close to amenities.

404 Oak St, Syracuse, NY 13203
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Syracuse Office Property for Sale
Pending
$599,900
13,000 SF

Syracuse Office Property for Sale

Office property available in Syracuse, New York, totaling 13,000 square feet.

901 Lodi St & Willow St E, Syracuse, NY 13203
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Prime Syracuse Office Building
$425,000
3,960 SF

Prime Syracuse Office Building

Downtown location, highway access, 3960 sq ft

117 Townsend St, Syracuse, NY 13203
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Syracuse Office Building - Prime Location
$425,000
4,696 SF

Syracuse Office Building - Prime Location

Modern office building, 4696 sq ft, 0.87 acres.

5575 Thompson Rd, Syracuse, NY 13214
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East Syracuse Mixed-Use Property
$2,600,000
11,654 SF

East Syracuse Mixed-Use Property

Versatile 11,654 sq ft commercial building

5930 Bowman Rd, East Syracuse, NY 13057
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Medical Center West: Camillus, NY
$7,500,000
106,834 SF

Medical Center West: Camillus, NY

Prime Medical Office Building, High Occupancy

5700 Genesee St, Camillus, NY 13031
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Syracuse Office Building: Value-Add Opportunity
$1,000,000
15,200 SF

Syracuse Office Building: Value-Add Opportunity

15,200 SF Office Building, 10% Occupancy

716 James St, Syracuse, NY 13203
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East Syracuse Restaurant/Retail Space
$295,000
2,373 SF

East Syracuse Restaurant/Retail Space

Prime location, vacant, owner financing possible.

6596 Old Collamer Rd, East Syracuse, NY 13057
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Prime Syracuse Office Building
$1,550,000
9,800 SF

Prime Syracuse Office Building

Value-add office building, high visibility

829 Genesee St, Syracuse, NY 13204
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Syracuse Office Building: Prime Location
$1,350,000
19,650 SF

Syracuse Office Building: Prime Location

Multi-tenant office building, high occupancy.

404 Oak St, Syracuse, NY 13203
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Former Ski Company
$399,000
4,441 SF

Former Ski Company

Medical offices • 4,441 SF

5785 Ny-80, Tully, NY 13159
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Syracuse Medical Office Building
$450,000
4,200 SF

Syracuse Medical Office Building

Prime Erie Blvd location, 4,200 SF, $450,000

1810 Erie Blvd, Syracuse, NY 13210
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Syracuse Medical Office Building
Contact for pricing
23,500 SF

Syracuse Medical Office Building

23,500 SF Medical Office, Syracuse, NY

3229 Genesee St, Syracuse, NY 13214
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Prime Baldwinsville Office/Retail Space
Contact for pricing
14,310 SF

Prime Baldwinsville Office/Retail Space

14,310 SF, 3-Story Building, High Traffic Area

36 Oswego St, Baldwinsville, NY 13027
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Turnkey Restaurant and Office Space
$495,000

Turnkey Restaurant and Office Space

4,800 SF property with restaurant and office space.

407 Tulip St, Salina, NY 13088
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S Salina St Office Building
$249,900
2,562 SF

S Salina St Office Building

Office building on a major commercial thoroughfare, great investment.

4709 S Salina St, Syracuse, NY 13205
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James Street Office Building For Sale
$695,000
17,888 SF

James Street Office Building For Sale

High-visibility Syracuse office building with ample parking and renovated restrooms.

750 James St, Syracuse, NY 13203
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Mixed-Use Building with Dental Practice
$185,000
2,600 SF

Mixed-Use Building with Dental Practice

2600 SF building with dental practice and apartment.

1500 Grant Blvd And Mayar St, Syracuse, NY
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Office Building Near Inner Harbor
$520,000

Office Building Near Inner Harbor

6400 SF office space with parking for 75 vehicles.

566 Spencer St, Syracuse, NY 13204
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Renovated Three-Story Village Office Building
$259,000
2,454 SF

Renovated Three-Story Village Office Building

2,454 SF office building renovated in 2018, village location.

514 Oswego St, Liverpool, NY 13088
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Mixed-Use Warehouse/Office/Retail Space
$2,900,000
42,416 SF

Mixed-Use Warehouse/Office/Retail Space

Versatile warehouse, office, and retail space near Route 690.

1641 E Genesee St, Syracuse, NY 13204
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Electronics Business Park Development Opportunity
$995,000
74,000 SF

Electronics Business Park Development Opportunity

Steel frame building shell suitable for high-tech, lab, manufacturing, office.

597 Electronics Pkwy, Liverpool, NY 13088
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Onondaga County, NY Office Properties & Spaces Investment Opportunities Market Analysis

Explore 1128 office properties & spaces for sale in Onondaga County, NY, showcased through 55 active listings on our real estate platform. These investment opportunities span a total of 51,791,582 square feet of properties for sale, with an estimated market value of $357,218,000.

Prices for office spaces in Onondaga County, NY start at $95,000, averaging $600,366, and reaching up to $17,195,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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