Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Office
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Port Saint Lucie, FL Office Properties & Spaces for Sale

    Notify Me
    List
    Map
    Lehigh Acres, FL Cape Coral, FL Port Charlotte, FL
    Medical Office For Sale
    $499,000
    2,041 SF

    Medical Office For Sale

    433-481 NW Prima Vista Blvd, Port Saint Lucie, FL

    Medical office in excellent condition, well-located near major highways.

    • Medical office in excellent condition, ready for immediate occupancy.
    • Well‑located between I‑95 and US Highway One for easy access.
    • Features five exam rooms with sinks.
    • Large waiting room and private doctor's office.
    • Equipped with a large nurses workstation.
    Updated: Jun 20, 2025
    View details
    Well-Maintained Property For Sale
    $1,290,000
    13,129 SF

    Well-Maintained Property For Sale

    7430-7448 S Federal Hwy, Port Saint Lucie, FL

    Well-maintained property with long-term occupants and upside potential.

    • Great short term upside potential
    • Great street visibility
    • Easy access
    • Well maintained property
    • Long term occupants
    Updated: Jan 31, 2025
    View details
    Based on your search, we've compiled 603 Potential Opportunities for your consideration. Besides 2 Active listings in Port Saint Lucie, FL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 593 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Medical Office in Excellent Condition
    $499,000
    0.02 Acres

    Medical Office in Excellent Condition

    Well-located medical office with five exam rooms for sale.

    Port St Lucie, FL 34983
    View details
    Multi-Tenant Investment Opportunity
    $1,499,999
    5,520 SF

    Multi-Tenant Investment Opportunity

    Industrial warehouse and office building on 0.92 acres.

    3802 OLEANDER AVENUE, Fort Pierce, FL 34982
    View details
    Shared Medical Co-Working Space
    Contact for pricing

    Shared Medical Co-Working Space

    Flexible, turnkey medical workspace in St. Lucie West.

    Port St Lucie, FL 34986
    View details
    Fort Pierce Warehouse with Office
    $230,000
    1,533 SF

    Fort Pierce Warehouse with Office

    1,035 SF warehouse with office space for sale.

    3781 Oleander Avenue, Fort Pierce, FL 34982
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Waterfront Development Site on Midway Road
    $549,000
    2.10 Acres

    Waterfront Development Site on Midway Road

    2.1-acre waterfront development site on the Midway Road corridor.

    2083 W MIDWAY ROAD, Fort Pierce, FL 34981
    View details
    Prime Commercial/Industrial Land Opportunity
    $549,500
    1.16 Acres

    Prime Commercial/Industrial Land Opportunity

    1.16-acre site ready for commercial or industrial development.

    3112 OLEANDER AVENUE, Fort Pierce, FL 34982
    View details
    Commercial Lots on Okeechobee Road
    $600,000
    18,295 SF

    Commercial Lots on Okeechobee Road

    Commercial lots available in high-traffic location near Okeechobee Rd.

    2602 Kerr Street, Fort Pierce, FL 34947
    View details
    Prime Development Land Opportunity
    $12,550,000
    251.00 Acres

    Prime Development Land Opportunity

    251 acres of land in a growing Fort Pierce location.

    4550 SHINN RD, Fort Pierce, FL 34945
    View details

    Explore Off-Market Properties in Port Saint Lucie, FL

    Consider similar Off-Market properties in Port Saint Lucie, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    510 Prt St Lucie Blvd

    510 Prt St Lucie Blvd

    OFFICE BUILDING • 3,522 SF
    Value Estimation
    $715,000
    510 Prt St Lucie Blvd, Port Saint Lucie, FL 34953-1943
    View details
    1401 Goldtree Dr Ste, Unit 102

    1401 Goldtree Dr Ste, Unit 102

    CONDOMINIUM OFFICES • 1,456 SF
    Value Estimation by Request
    1401 Goldtree Dr Ste, Port Saint Lucie, FL 34952-7584
    View details
    2000 Prt St Lucie Blvd

    2000 Prt St Lucie Blvd

    OFFICE BUILDING • 9,200 SF
    Value Estimation
    $1,810,000
    2000 Prt St Lucie Blvd, Port Saint Lucie, FL 34952-5546
    View details
    2299 Kail St

    2299 Kail St

    OFFICE BUILDING • 5,351 SF
    Value Estimation
    $1,475,000
    2299 Kail St, Port Saint Lucie, FL 34984
    View details
    14201 Waterfall Ln

    14201 Waterfall Ln

    OFFICE BUILDING • 3,600 SF
    Value Estimation by Request
    14201 Waterfall Ln, Port Saint Lucie, FL 34987-7788
    View details
    451 Bethany Dr

    451 Bethany Dr

    PROFESSIONAL BUILDING • 19,872 SF
    Value Estimation
    $4,250,000
    451 Bethany Dr, Port Saint Lucie, FL 34986-1964
    View details
    1095 Saint Lucie W Blvd

    1095 Saint Lucie W Blvd

    PROFESSIONAL BUILDING • 69,361 SF
    Value Estimation by Request
    1095 Saint Lucie W Blvd, Port Saint Lucie, FL 34986-1719
    View details
    1400 Goldtree Dr

    1400 Goldtree Dr

    CONDOMINIUM OFFICES • 1,200 SF
    Value Estimation by Request
    1400 Goldtree Dr, Port Saint Lucie, FL 34952-7582
    View details
    1400 Goldtree Dr

    1400 Goldtree Dr

    CONDOMINIUM OFFICES • 1,440 SF
    Value Estimation by Request
    1400 Goldtree Dr, Port Saint Lucie, FL 34952-7582
    View details
    1400 Goldtree Dr

    1400 Goldtree Dr

    CONDOMINIUM OFFICES • 1,440 SF
    Value Estimation by Request
    1400 Goldtree Dr, Port Saint Lucie, FL 34952-7582
    View details
    1400 Goldtree Dr

    1400 Goldtree Dr

    CONDOMINIUM OFFICES • 1,920 SF
    Value Estimation by Request
    1400 Goldtree Dr, Port Saint Lucie, FL 34952-7582
    View details
    8301 Holley Tree Trl

    8301 Holley Tree Trl

    OFFICE BUILDING • 7,680 SF
    Value Estimation by Request
    8301 Holley Tree Trl, Port Saint Lucie, FL 34986-3040
    View details
    1385 Prt St Lucie Blvd

    1385 Prt St Lucie Blvd

    OFFICE BUILDING • 3,696 SF
    Value Estimation
    $750,000
    1385 Prt St Lucie Blvd, Port Saint Lucie, FL 34952
    View details
    738 Prima Vis Blvd

    738 Prima Vis Blvd

    PROFESSIONAL BUILDING • 1,400 SF
    Value Estimation by Request
    738 Prima Vis Blvd, Port Saint Lucie, FL 34952-2261
    View details
    2765 Edgarce St

    2765 Edgarce St

    OFFICE BUILDING (MULTI-STORY) • 1,320 SF
    Value Estimation by Request
    2765 Edgarce St, Port Saint Lucie, FL 34953
    View details
    737 Prt St Lucie Blvd

    737 Prt St Lucie Blvd

    OFFICE BUILDING • 6,260 SF
    Value Estimation
    $845,000
    737 Prt St Lucie Blvd, Port Saint Lucie, FL 34953-2618
    View details
    462 Prt St Lucie Blvd

    462 Prt St Lucie Blvd

    OFFICE BUILDING • 2,414 SF
    Value Estimation by Request
    462 Prt St Lucie Blvd, Port Saint Lucie, FL 34984-5174
    View details
    2717 Swe Calabria Cir

    2717 Swe Calabria Cir

    OFFICE BUILDING • 3,220 SF
    Value Estimation by Request
    2717 Swe Calabria Cir, Port Saint Lucie, FL 34953-4226
    View details
    8881 Us Hwy 1st 1

    8881 Us Hwy 1st 1

    CONDOMINIUM OFFICES • 63,910 SF
    Value Estimation
    $10,640,000
    8881 Us Hwy 1st 1, Port Saint Lucie, FL 34952-3401
    View details
    1801 Hillmoor Dr Ste C-102

    1801 Hillmoor Dr Ste C-102

    MEDICAL BUILDING • 1,530 SF
    Value Estimation by Request
    1801 Hillmoor Dr Ste C-102, Port Saint Lucie, FL 34952-7550
    View details
    1801 Hillmoor Dr Ste A-101

    1801 Hillmoor Dr Ste A-101

    MEDICAL BUILDING • 1,530 SF
    Value Estimation by Request
    1801 Hillmoor Dr Ste A-101, Port Saint Lucie, FL 34952-7545
    View details
    9702 Reserve Blvd

    9702 Reserve Blvd

    OFFICE BUILDING • 7,359 SF
    Value Estimation
    $585,000
    9702 Reserve Blvd, Port Saint Lucie, FL 34986-3264
    View details

    Port Saint Lucie, FL Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 595 office properties & spaces for sale in Port Saint Lucie, FL on our real estate platform. These investment opportunities span a total of 15,170 square feet of properties for sale, with an estimated market value of $1,789,000.

    Sale prices for office spaces in Port Saint Lucie, FL start at $499,000, averaging $894,500, and reaching up to $1,290,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Browse Office properties & Spaces for Sale Near Port Saint Lucie, FL

    Popular Searches in Port Saint Lucie, FL

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!