Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Office
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Columbia County, FL Office Properties & Spaces for Sale

    9 results
    List
    Map
    Main Boulevard Office Building
    $395,000
    1,823 SF

    Main Boulevard Office Building

    229 SW Main Blvd, Lake City, FL 32025

    Class B office building on a corner lot for sale.

    • High‑visibility location on Main Boulevard with 13,000\u00b1 daily traffic count.
    • Includes a second building suitable for commercial use, lease, or residential conversion.
    • Ample parking and two access points on a corner lot.
    • Features a radio tower, offering potential additional income or utility.
    • Secure basement for file storage and utilities.
    Updated: Jan 27
    View details
    Lake City Professional Office
    $295,000
    1,208 SF

    Lake City Professional Office

    1166 SW Main Blvd, Lake City, FL 32025

    Commercial office building with reception, exam rooms, and bathroom.

    • Great location on Main Blvd.
    • Previously used as a dental office, suitable for similar practices.
    • Includes 4 exam rooms/offices.
    • Reception/lobby area with front desk and window.
    • Brick construction.
    Updated: Dec 22, 2025
    View details
    Remodeled Home Office Building
    $259,900
    2,442 SF

    Remodeled Home Office Building

    Remodeled office building with live-work potential in Lake City.

    340 SE Country Club Rd, Lake City, FL 32025
    View details
    Lake City Executive Park Complex
    $1,200,000
    16,050 SF

    Lake City Executive Park Complex

    Fully leased office complex near I-75, a steady income generator.

    260 S Marion Ave, Lake City, FL 32025
    View details
    Lake City Office Space Available
    $199,654
    1,529 SF

    Lake City Office Space Available

    Professional office space with multiple offices, conference room, and kitchen.

    654 Baya Dr, Lake City, FL 32025
    View details
    Commercial Building in Downtown Lake
    $249,000

    Commercial Building in Downtown Lake

    Commercial building in Lake City suitable for store or office.

    508 N Marion Ave, Lake City, FL 32055
    View details
    Live and Work Opportunity
    $669,000
    7,200 SF

    Live and Work Opportunity

    7,200 SF property with warehouse and residential space.

    709 SW Morning Star Gln, Fort White, FL 32038
    View details
    Lake City Mixed-Use Investment Opportunity
    $650,000
    1,770 SF

    Lake City Mixed-Use Investment Opportunity

    Gas station, hotel, restaurant; prime location.

    3827 Us Highway 441, Lake City, FL 32055
    View details
    Lake City Mixed-Use Commercial Building
    $595,000
    3,168 SF

    Lake City Mixed-Use Commercial Building

    Highway 41 Frontage, 3168 SF, $595,000

    2832 Main Blvd, Lake City, FL 32025
    View details
    Based on your search, we've compiled 383 Potential Opportunities for your consideration. Besides 9 Active listings in Columbia County, FL, we suggest exploring several alternatives: similar 370 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    7.64 Acres Commercial Land
    $699,000
    7.64 Acres

    7.64 Acres Commercial Land

    Commercial zoned land in a growing area with road frontage.

    782 SW Sisters Welcome Rd, Lake City, FL 32025
    View details
    Commercial Land in Lake City
    $69,500
    2.65 Acres

    Commercial Land in Lake City

    2.645 acres of commercial land for sale in Lake City, Florida.

    SE Baya/Margaret, Lake City, FL 32025
    View details
    Commercial Lot Near I-75
    $250,000
    1.02 Acres

    Commercial Lot Near I-75

    Commercial land in a rapidly developing area near major routes.

    637 SW Commerce Dr, Lake City, FL 32025
    View details
    Lake City Commercial Lot Available
    $400,000
    2.04 Acres

    Lake City Commercial Lot Available

    Prime commercial lot in a rapidly developing area.

    SW Commerce Dr, Lake City, FL 32025
    View details

    Explore Off-Market Properties in Columbia County, FL

    Consider similar Off-Market properties in Columbia County, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    782 Sisters Welcome Rd

    782 Sisters Welcome Rd

    MEDICAL BUILDING • 4,294 SF
    Value Estimation by Request
    782 Sisters Welcome Rd, Lake City, FL 32025-0442
    View details
    879 Main Blvd

    879 Main Blvd

    Individual retail properties
    Value Estimation by Request
    879 Main Blvd, Lake City, FL 32025
    View details
    330 Main Blvd

    330 Main Blvd

    OFFICE (GENERAL) • 1,394 SF
    Value Estimation by Request
    330 Main Blvd, Lake City, FL 32025-7048
    View details
    1802 Us Hwy 441

    1802 Us Hwy 441

    OFFICE (GENERAL) • 1,690 SF
    Value Estimation by Request
    1802 Us Hwy 441, Lake City, FL 32055-4345
    View details
    4389 Us Hwy 90

    4389 Us Hwy 90

    OFFICE (GENERAL) • 3,200 SF
    Value Estimation
    $535,000
    4389 Us Hwy 90, Lake City, FL 32055-4877
    View details
    4601 Us Hwy 90

    4601 Us Hwy 90

    MEDICAL BUILDING • 5,680 SF
    Value Estimation by Request
    4601 Us Hwy 90, Lake City, FL 32055-4880
    View details
    215 Prosperity Pl

    215 Prosperity Pl

    MEDICAL BUILDING • 4,620 SF
    Value Estimation by Request
    215 Prosperity Pl, Lake City, FL 32024-0699
    View details
    236 Alachua Ave

    236 Alachua Ave

    OFFICE (GENERAL) • 1,331 SF
    Value Estimation by Request
    236 Alachua Ave, Lake City, FL 32025-7007
    View details
    244 Wilson St

    244 Wilson St

    OFFICE (GENERAL) • 732 SF
    Value Estimation by Request
    244 Wilson St, Lake City, FL 32055-0510
    View details
    220 Marion Ave

    220 Marion Ave

    OFFICE (GENERAL) • 4,250 SF
    Value Estimation by Request
    220 Marion Ave, Lake City, FL 32025-7058
    View details
    413 Mccloskey Ave

    413 Mccloskey Ave

    OFFICE (GENERAL) • 4,168 SF
    Value Estimation
    $685,000
    413 Mccloskey Ave, Lake City, FL 32055-6412
    View details
    1166 Baya Dr

    1166 Baya Dr

    OFFICE (GENERAL) • 1,497 SF
    Value Estimation by Request
    1166 Baya Dr, Lake City, FL 32025-5538
    View details
    372 Duval St

    372 Duval St

    OFFICE (GENERAL) • 81,848 SF
    Value Estimation
    $8,270,000
    372 Duval St, Lake City, FL 32055-3990
    View details
    630 Duval St

    630 Duval St

    OFFICE (GENERAL) • 1,448 SF
    Value Estimation by Request
    630 Duval St, Lake City, FL 32055-5801
    View details
    Baya Dr

    Baya Dr

    Office space • 1,152 SF
    Value Estimation by Request
    0 Baya Dr, Lake City, FL 32025
    View details

    Columbia County, FL Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 379 office properties & spaces for sale in Columbia County, FL, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 20,664,949 square feet of properties for sale, with an estimated market value of $121,234,554.

    Sale prices for office spaces in Columbia County, FL start at $50,000, averaging $425,384, and reaching up to $9,290,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Office Properties & Spaces by market

    Browse Office Properties & Spaces for Sale Near Columbia, FL

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!