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    Salem, VA
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    Salem, VA Office Spaces for Lease

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    Roanoke, VA Cave Spring, VA Hollins, VA
    10 results
    Salem Retail/Office Space Available
    $12 SF/Yr
    5,000 SF
    Salem Retail/Office Space Available

    107 W Main St, Salem, VA 24153

    Prominent Main Street location suitable for retail or office uses.
    • Prominent Main Street location in downtown Salem.
    • Custom buildout opportunity to tenant's specifications.
    • High‑traffic location with 15,000 AWT.
    • Suitable for office and retail uses.
    • May be subdivided into two 2,500 square foot suites.
    Updated: Mar 6
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    Adaptable Commercial Property For Rent
    $12 SF/Yr
    5,000 SF
    Adaptable Commercial Property For Rent

    1005 E Main St, Salem, VA

    5,000 SF commercial property with flexible floor plan.
    • 5,000 SF single‑story brick commercial property
    • Suites available starting at 1,000 SF
    • Flexible floor plan suitable for single or multi‑tenant use
    • 15 dedicated customer parking spaces
    • Additional lot for supplemental parking
    Updated: Aug 11, 2025
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    Retail/Office Center in Salem
    Contact for pricing
    Retail/Office Center in Salem

    Retail/office center with excellent location, visibility, and ample parking.

    2105 Apperson Dr, Salem, VA 24153

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    Downtown Salem Office Space Available
    $18 SF/Yr
    4,085 SF
    Downtown Salem Office Space Available

    Two-story office building in the heart of Downtown Salem.

    306 E Main St, Salem, VA

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    Turn-Key Ready End Cap Space
    $12 SF/Yr
    2,250 SF
    Turn-Key Ready End Cap Space

    Renovated 2,250 SF space suitable for various business uses.

    2105-2119 Apperson Dr, Salem, VA

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    Downtown Salem Office Building
    Contact for pricing
    15,130 SF
    Downtown Salem Office Building

    Two-story office building in the heart of Salem, Virginia.

    110 E Main St, Salem, VA

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    Industrial Space Available For Lease
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    324,000 SF
    Industrial Space Available For Lease

    324,000 SF industrial space available for lease.

    1501 Roanoke Blvd, Salem, VA 24153

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    Retail Space in Lakeside Plaza
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    Retail Space in Lakeside Plaza

    Retail space for lease in Kroger-anchored Lakeside Plaza.

    161 Electric Road, Salem, VA 24153

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    Salem Office Space For Rent
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    6,600 SF
    Salem Office Space For Rent

    6,600 SF office space with access to Roanoke Valley.

    1701 Midland Rd, Salem, VA 24153

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    Retail/Office Space For Rent
    Contact for pricing
    5,000 SF
    Retail/Office Space For Rent

    Retail and office spaces available for rent.

    110 E. Main Street, Salem, VA 24053

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    Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 10 Active listings in Salem, VA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Modern Industrial Building For Lease
    Contact for pricing
    5,000 SF
    Modern Industrial Building For Lease

    5,000 SF industrial building with high ceilings and drive-in access.

    3656 Peters Creek Rd, Roanoke, VA 24018

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    Office Building Near Lewis-Gale Hospital
    $16 SF/Yr
    62,171 SF
    Office Building Near Lewis-Gale Hospital

    Two-story office building with easy access and ample parking.

    1325 Electric Rd, Roanoke, VA

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    Two-Story Office Building For Rent
    $16 SF/Yr
    Two-Story Office Building For Rent

    Two-story office building with easy access and ample parking.

    1325 Electric Road, Roanoke, VA 24018

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    North Roanoke Office Space Available
    $15 SF/Yr
    North Roanoke Office Space Available

    First-class office space in a sought-after North Roanoke office park.

    5430 Peters Creek Road, Roanoke, VA 24019

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    Similar Spaces for Sale in Salem, VA

    Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

    Salem Commercial Building For Sale
    $495,000
    0.45 Acres
    Salem Commercial Building For Sale

    Well-maintained commercial building suitable for office, service, or retail.

    904 Apperson Dr, Salem, VA 24153

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    Salem, VA Office Building For Sale
    $995,000
    5,163 SF
    Salem, VA Office Building For Sale

    Multi-tenant office building in Salem's Electric Road corridor.

    1101 Electric Rd, Salem, VA 24153

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    Salem Office | Manufacturing | Lab
    $670,000
    5,280 SF
    Salem Office | Manufacturing | Lab

    Well-appointed office and lab/manufacturing space in Salem.

    1405 Mill Race Dr, Salem, VA 24153

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    Well-Maintained Office/Retail Building For Sale
    $495,000
    1,455 SF
    Well-Maintained Office/Retail Building For Sale

    Pristine building suitable for office, service, or retail use.

    904 Apperson Dr, Salem, VA 24153

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    Salem Retail/Office Building For Sale
    $1,350,000
    3,179 SF
    Salem Retail/Office Building For Sale

    Highly visible retail/office building at signalized intersection in Salem, VA.

    1432 Apperson Dr, Salem, VA 24153

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    Multi-Tenant Office Building For Sale
    $1,425,000
    7,416 SF
    Multi-Tenant Office Building For Sale

    7,500 SF multi-tenant office building on 1.44 acres.

    1618 W Main St, Salem, VA 24153

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    Developable Land For Sale
    $149,950
    0.56 Acres
    Developable Land For Sale

    0.56 AC developable land, ideal for retail, restaurant, or office.

    2005 E Main St, Salem, VA 24153

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Land For Lease
    $285,000 SF/Yr
    Prime Commercial Land For Lease

    3 acres of B-3 zoned land with city amenities.

    220 Silver Lake Road, Church Hill, TN 37642

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    Commercial Land at Major Intersection
    $400,000 SF/Yr
    Commercial Land at Major Intersection

    8 acres of commercial land for ground lease.

    12640 Lord Fairfax Hwy, Boyce, VA 22620

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    Land Lease Opportunity in Waxhaw
    $8,000/Mo
    Land Lease Opportunity in Waxhaw

    5.341-acre commercial land for lease in a high-growth area.

    5325 Waxhaw Marvin Road, Waxhaw, NC 28173

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    Commercial Land Near Interstate 40
    $499,900 SF/Yr
    1,860 SF
    Commercial Land Near Interstate 40

    3.96 acres with high visibility near Interstate 40.

    310 Goose Creek Road, Dandridge, TN 37725

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    Salem, VA Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Salem, VA with 10 listings featured on our commercial real estate exchange. The current inventory includes 16,335 square feet of properties with an estimated lease value of $54 SF/Yr.

    Estimated lease rates for Office Spaces in Salem, VA begin at $12 SF/Yr, with an average of $13 SF/Yr and extend to $18 SF/Yr.
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    Most Searched ZIP Codes in Salem, VA

    • 24153
    • 24053

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