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    Charleston, SC Office Properties & Spaces for Lease

    108 results
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    Downtown Charleston
    Contact for pricing

    Downtown Charleston

    Discover many ways to work your way in Downtown Charleston

    170 Floors, Charleston, SC 29401
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    Charleston Historic District Office Space
    $22 SF/Yr
    4,204 SF

    Charleston Historic District Office Space

    2 Cumberland St, Charleston, SC 29401

    Renovated office suites with harbor views in historic Charleston.

    • Rare views of Charleston Harbor, Ravenel Bridge, US Customs House, and USS Yorktown.
    • Newly renovated suites with modern finishes ready for immediate occupancy.
    • Located in the historic district of Charleston's peninsula.
    • Open floorplans provide functional versatility.
    • Suites available on the 2nd and 3rd floors, each with 4,204 RSF.
    Updated: Mar 6
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    Downtown Charleston Freestanding Building
    $29 SF/Yr
    14,518 SF

    Downtown Charleston Freestanding Building

    276 East Bay Street, Charleston, SC 29401

    Freestanding building in historic downtown Charleston with on-site parking.

    • Prime location in historic downtown Charleston, walking distance to restaurants and shopping.
    • Rare on‑site parking with 38 spaces.
    • High traffic volume (28,300 VPD) and excellent walkability (83%).
    • Flexible space options: lease entire building or subdivide by floor.
    • Close proximity to Union Pier development and future College of Charleston Business School.
    Updated: Nov 21, 2025
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    Wappoo Creek Office Space Available
    $20 SF/Yr
    2,944 SF

    Wappoo Creek Office Space Available

    Office space for lease in a convenient Charleston location.

    125 Wappoo Creek Dr, Charleston, SC 29412
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    Daniel Island Office Space Available
    $32 SF/Yr
    3,975 SF

    Daniel Island Office Space Available

    Second-floor office suite in Daniel Island's Town Center.

    115 Riverlanding Dr, Charleston, SC
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    James Island Office Space Available
    $20 SF/Yr
    2,200 SF

    James Island Office Space Available

    Office space for lease in a convenient Charleston location.

    125 Wappoo Creek Dr, Charleston, SC 29412
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    Class A Office Space
    $43 SF/Yr
    9,675 SF

    Class A Office Space

    Multi-tenant office building in Charleston's Historic District.

    100 Calhoun Street, Charleston, SC 29401
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    Charleston Historic District Office Space
    $22 SF/Yr
    16,816 SF

    Charleston Historic District Office Space

    Renovated office suites with harbor views in Charleston's historic district.

    2 Cumberland St, Charleston, SC 29401
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    Renovated Office Space on King
    $23 SF/Yr
    2,631 SF

    Renovated Office Space on King

    Renovated office space in Charleston's 'Dine & Design' district.

    579 King Street, Charleston, SC 29403
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    Class A Office Space Available
    $22 SF/Yr
    20,028 SF

    Class A Office Space Available

    Class A office suite for lease in growing Daniel Island/Cainhoy.

    1951 Clements Ferry, Charleston, SC 29492
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    Historic Mixed-Use Building on King
    $35 SF/Yr
    10,673 SF

    Historic Mixed-Use Building on King

    Renovated mixed-use building in Charleston's Upper King Street corridor.

    438 King St, Charleston, SC 29403
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    Office Complex Near Citadel Mall
    $24 SF/Yr
    9,275 SF

    Office Complex Near Citadel Mall

    Three-building office complex on 10.82 acres with ample parking.

    1 South Park Circle, Charleston, SC 29407
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    Move-in Ready Office/Retail Space
    $44 SF/Yr

    Move-in Ready Office/Retail Space

    Office or retail space with on-site parking on Shem Creek.

    103 Church Street, Charleston, SC 29464
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    Savannah Highway Retail/Office Space
    $30 SF/Yr
    4,168 SF

    Savannah Highway Retail/Office Space

    Freestanding building with excellent visibility and ample parking.

    422 Savannah Hwy, Charleston, SC
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    Furnished Office Building Sublease Opportunity
    $24 SF/Yr
    78,394 SF

    Furnished Office Building Sublease Opportunity

    Well-appointed, fully furnished office building available for sublease.

    125 Fairchild Street, Charleston, SC, USA, Charleston, SC 29492
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    Class A Office Space Available
    $49 SF/Yr
    3,851 SF

    Class A Office Space Available

    Up to 3,851 SF of fully up-fitted Class A office space.

    651 Meeting St, Charleston, SC
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    West Ashley Medical Office Space
    $22 SF/Yr
    3,000 SF

    West Ashley Medical Office Space

    3,000 SF office space in the heart of West Ashley.

    1027 Physicians Dr, Charleston, SC
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    Downtown Charleston Office Space
    $29 SF/Yr

    Downtown Charleston Office Space

    Office space for rent in Charleston's growing Upper Peninsula.

    11 Isabella St Suite A, Charleston, SC 29403
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    Savannah Highway Retail/Office Building
    $16 SF/Yr
    2,800 SF

    Savannah Highway Retail/Office Building

    Free-standing 2,800 SF retail or office building for lease.

    2413 Savannah Hwy, Charleston, SC
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    Charleston Peninsula Office Space
    $36 SF/Yr
    7,390 SF

    Charleston Peninsula Office Space

    Cool office space in pioneering mixed-use redevelopment on Charleston Peninsula.

    1501 King Street Extension, Charleston, SC 29405
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    Renovated Office/Retail Building on East Bay
    $30 SF/Yr
    3,789 SF

    Renovated Office/Retail Building on East Bay

    Modern, flexible office/retail space in prime downtown location.

    341 East Bay St, Charleston, SC
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    Office Space on Jessen Lane
    $20 SF/Yr
    1,500 SF

    Office Space on Jessen Lane

    Highly visible office space in a rapidly growing commercial corridor.

    405 Jessen Ln, Charleston, SC
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    Downtown Charleston Office Space Available
    $25 SF/Yr
    2,040 SF

    Downtown Charleston Office Space Available

    Office suites for lease in downtown Charleston's office district.

    180 Meeting St, Charleston, SC
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    Available Flex and Office Space
    $13 SF/Yr
    58,444 SF

    Available Flex and Office Space

    Flex and office spaces for lease in North Charleston.

    8085 Rivers Ave, N Charleston, SC
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    Charleston, SC Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Charleston, SC with 108 listings featured on our commercial real estate exchange. The current inventory includes 30,634,746,120 square feet of properties with an estimated lease value of $1,420 /Mo.

    Estimated lease rates for Office properties & Spaces in Charleston, SC begin at $12 SF/Yr, with an average of $30 SF/Yr and extend to $84 SF/Yr.
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    Browse Office properties & Spaces for Lease Near Charleston, SC

    Popular Searches in Charleston, SC

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    Most Searched ZIP Codes in Charleston, SC

    • 29401
    • 29407
    • 29492
    • 29403
    • 29405
    • 29412
    • 29406
    • 29414
    • 29418
    • 29464

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