Moncks Corner, SC Office Spaces for Rent & Lease

Updated: Mar 6

Moncks Corner Medical Office Sublease

422 Drive In Lane, Moncks Corner, SC 29461

$22 SF/Yr

7,490 sqft

Free‑standing ±7,490 SF Class A medical office building.
Ideal for various medical uses (walk‑in clinic, orthodontist, infusion center, dentist, etc.) or another dialysis clinic.
Sublease until 1/31/2036.
Located in Moncks Corner's developing retail district near Walmart Supercenter and Tractor Supply Co.
Ample parking along the sides and rear.

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Updated: Nov 24, 2025

Medical Office Space Available

3508 S Live Oak Dr, Moncks Corner, SC

$32 SF/Yr

8,000 sqft

8,000 SF medical office space available.
Located on the third floor.
Lease rate is $24/SF plus $8 CAM.
Coastal Cardiology occupies the second floor.
Contact Bob Glover, CCIM at 843‑572‑0000.

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Moncks Corner Downtown Office Space

337 E Main St, Moncks Corner, SC

$16 SF/Yr

1,000 sqft

Prominent building in downtown Moncks Corner with flexible zoning.

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Moncks Corner Commercial Space For Lease

2700 US-52, Moncks Corner, SC 29461

$14 SF/Yr

10,960 sqft

Commercial lease featuring indoor space, outdoor storage, and ample parking.

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Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 4 Active listings in Moncks Corner, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

SC, Summerville - 700 Nexton Square Drive

700 Nexton Square Dr, Summerville, SC 29483

Contact for pricing

(972) 764-8885

Discover many ways to work your way in SC, Summerville - 700 Nexton Square Drive

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Office/Warehouse Space on 4.33 Acres

3245 Benchmark Drive #Available Space, Ladson, SC 29456

$6.75 SF/Yr

60,000 sqft

60,000 SF office/warehouse with fenced yard, available June 2026.

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Flex Space with Rear Lay-Down Yard

806-A Beckham Lane, Summerville, SC 29483

Contact for pricing

3,400 sqft

Flex building with office buildout, 16’ clear warehouse, and a rear lay-down yard sized to maneuver tractor trailers.

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Turnkey Dental Office Sublease Opportunity

9403 Hwy 78 # 201, Ladson, SC 29456

$25 SF/Yr

Sublease opportunity for a turnkey dental office in Ladson.

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Similar Spaces for Sale in Moncks Corner, SC

Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

Moncks Corner Office For Sale

219 W Main St, Moncks Corner, SC 29461

$350,000

1,441 sqft

Office space available in Moncks Corner, South Carolina.

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Moncks Corner Retail/Office Space

111 A & B N Live Oak, Moncks Corner, SC

Contact for pricing

3,000 sqft 0.24 AC lot

3,000 SF space in the heart of Moncks Corner.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Land Lease Opportunity in Waxhaw

5325 Waxhaw Marvin Road, Waxhaw, NC 28173

$8,000/Mo

5.341-acre commercial land for lease in a high-growth area.

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Prime Development Opportunity in Greenville

39 Airpark Ct, Greenville, SC 29607

Contact for pricing

1.27 acre interstate-visible land for ground lease or build-to-suit.

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Waterfront Commercial Land Parcel

Old Bridge Street, Jacksonville, NC 28540

$4,500/Mo

Commercially zoned waterfront parcel with deep water frontage and bulkhead, located within city limits.

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Commercial Land Build-to-Suit Opportunity

2683 Henderson Drive, Jacksonville, NC 28546

$4,000/Mo

2,400 sqft

Commercial land available for build-to-suit in Jacksonville, NC.

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Moncks Corner, SC Office Spaces Market Trends and Statistics

Explore Office Spaces leasing options in Moncks Corner, SC with 4 listings featured on our commercial real estate exchange. The current inventory includes 27,450 square feet of properties with an estimated lease value of $84 SF/Yr.

Estimated lease rates for Office Spaces in Moncks Corner, SC begin at $14 SF/Yr, with an average of $21 SF/Yr and extend to $32 SF/Yr.