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    Found 147 office space listings for lease in Lancaster, PA, averaging $26/SF/YR. Use lease type data to compare options faster.
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    Office Suite with Atrium
    Office Suite with Atrium

    203-1891 Santa Barbara Dr, Lancaster, PA 17601

    Class B
    Contact for pricing
    Highway access

    A central atrium brings daylight into the office building’s interior.

    Atrium
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    Medical Office Suite
    Medical Office Suite

    160 N Pointe Boulevard Unit 106, Lancaster, PA 17601

    Contact for pricing
    Built 1989
    Highway access

    Recently updated shared areas and access to Rt. 30 support a professional office setting.

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    Office Unit with Parking
    Office Unit with Parking

    1808 Colonial Village Ln Unit 103, Lancaster, PA 17601

    Contact for pricing
    Built 1993

    Tenant-occupied office space at a Lancaster address with on-site parking and convenient access.

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    Move-in Ready Greenfield Office Space
    Move-in Ready Greenfield Office Space

    1830 Colonial Village Lane, Lancaster, PA 17601

    Contact for pricing
    95–159 people  23,936 sqft  Built 1991

    Class A office space in Greenfield, move-in ready condition.

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    Office Condominium Suites
    Office Condominium Suites

    32 East Roseville Road C, Lancaster, PA 17601

    Contact for pricing
    Built 1988  Multi-tenant
    Highway access + Road access

    Office condos in a seven-building campus setting with private entrances, second-floor space, and full basements.

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    Medical Office Sublease Suite
    Medical Office Sublease Suite

    730 Eden Rd, Lancaster, PA 17601

    Contact for pricing
    Built 2008

    Elevator-served second-floor medical office suite available for sublease, encompassing the entire second floor.

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    Seven-Office Suite
    Seven-Office Suite

    201-1860 Charter Ln, Lancaster, PA 17601

    Contact for pricing
    7 private offices  1 meeting room

    A conference room, kitchenette, and shared collaborative area complement the private workspaces.

    Kitchenette  Collaborative area
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    ADA-Accessible Medical Office Building
    ADA-Accessible Medical Office Building

    802 New Holland Ave, Lancaster, PA 17602

    Triple net (NNN)
    Contact for pricing
    10,694 sqft
    Highway access

    Elevator-served medical office space in an ADA-accessible building, currently set up for primary and specialty medical services.

    ADA-accessible  Elevator-served  Pylon signage
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    Class A Medical Office Building
    Class A Medical Office Building

    205-160 N Pointe Blvd, Lancaster, PA 17601

    Contact for pricing

    Recently remodeled common areas in a Class A office building offer a polished setting for medical and professional tenants.

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    Professional Office Suite
    Professional Office Suite

    780 Eden Rd, Lancaster, PA 17601

    Contact for pricing
    8–13 people  2,025 sqft
    Highway access

    Professional office environment within Moore Business Park, offering abundant parking and signage opportunities with easy Route 30/Route 222 access.

    Pylon and signage opportunities
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    Manheim Township Class A Office
    Manheim Township Class A Office

    120 N Pointe Blvd, Lancaster, PA

    Triple net (NNN)
    Contact for pricing
    6–10 people  1 space  1,550 sqft  1.72 acres

    First floor corner office suite in premier location.

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    Modern Office Units
    Modern Office Units

    103-1808 Colonial Village Ln, Lancaster, PA 17601

    Contact for pricing

    Clean, well-maintained office space offers convenient access and on-site parking.

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    Class A+ Office Suites Available
    Class A+ Office Suites Available

    850 Greenfield Rd, Lancaster, PA 17601

    Modified gross
    Contact for pricing
    25–43 people  1 space  6,468 sqft

    Turn-key office suites in pristine business atmosphere for rent.

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    Street-Level Office Suite
    Street-Level Office Suite

    29 E King Street Suite 101, Lancaster, PA 17602

    Contact for pricing
    Built 1900

    For lease office suite on E King St, located just past N. Christian St.

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    Lancaster Commercial Space For Rent
    Lancaster Commercial Space For Rent

    600 Eden Rd E, Lancaster, PA 17601

    Contact for pricing
    Built 1986

    Commercial space available for rent in Lancaster, Pennsylvania.

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    Office Suite with Street-Level Entry
    Office Suite with Street-Level Entry

    120-354 N Prince St, Lancaster, PA 17603

    Contact for pricing

    Downtown CBD office suite with street-level direct entry, elevator access, and a signage panel facing Prince and Lemon.

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    Office Building with Surface Parking
    Office Building with Surface Parking

    850 GREENFIELD ROAD, Lancaster, PA 17601

    Contact for pricing
    Built 1999

    Office building in Lancaster, PA with designated front-of-building surface parking access via nearby traffic lights.

    500 parking spaces
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    Downtown Office Suite with Parking
    Downtown Office Suite with Parking

    100-354 N Prince St, Lancaster, PA 17603

    Contact for pricing

    Suite 100 offers multiple offices and conference rooms with elevator access and 17 on-site parking spaces.

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    Sublease Office Suites
    Sublease Office Suites

    700 Indian Springs Dr, Lancaster, PA 17601

    Contact for pricing
    21–35 people  5,331 sqft

    Multiple office suites are available for sublease, with flexible layouts including private offices, open areas, and breakrooms.

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    Flexible Office Units
    Flexible Office Units

    700 Indian Springs Dr, Lancaster, PA 17601

    Contact for pricing
    26–43 people  6,506 sqft
    Highway access

    Sublease suites offer private offices, cubicles, open areas, and breakrooms in multiple build-out configurations.

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    Office Units with Secure Access
    Office Units with Secure Access

    102-131 E Grant St, Lancaster, PA 17602

    $18,000/Mo

    Professional workspace offers private offices, exposed brick, and spiral ductwork in a walkable city setting.

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    Medical Office Suite
    Medical Office Suite

    208-1860 Charter Ln, Lancaster, PA 17601

    Contact for pricing

    Flexible office suite with two private restrooms and a kitchenette, available Spring of 2026.

    Private rest rooms  Kitchenette  Flexible floorplan
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    Professional Office Suites Available
    Professional Office Suites Available

    53-61 N Duke St, Lancaster, PA

    Contact for pricing
    4–6 people  1,014 sqft  0.47 acres

    Office suites for rent in the Central Business District.

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    Lancaster City Versatile Leasing Opportunity
    Lancaster City Versatile Leasing Opportunity

    220 Hazel St, Lancaster, PA

    Triple net (NNN)
    Contact for pricing
    3,500 sqft

    Prime property with retail, office, and warehouse spaces for lease.

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