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Ephrata, PA Office Spaces for Lease

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10 properties
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Retail Space With Tailgate Dock
Updated: Apr 8
Retail Space With Tailgate Dock

400 W MAIN Street, Ephrata, PA 17522

$8,223/Mo
5.00 AC lot
14,097 sq. ft. of first‑floor office and retail space
Five‑room layout with three large sales and display rooms
Dedicated 8x8 tailgate dock
Two powder rooms, private office, lunch room, and shop
5‑acre parcel with parking lot
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Office Units With Private Offices
Updated: Aug 14
Office Units With Private Offices

1413 W Main St, Ephrata, PA 17522

$1,995/Mo
Fresh paint and new flooring throughout the building
Large open room for conference use or cubicle setup
Several private offices plus reception area
New kitchenette, storage closets, and built‑ins
2 powder rooms and 7 parking spaces included
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Multiroom Office Suite
Multiroom Office Suite

4-333 N State St, Ephrata, PA 17522

$1,400/Mo
Downstairs

The lower-level suite offers a layout with several rooms for office or studio use.

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Office Space for Lease
Office Space for Lease

860 N Reading Rd, Ephrata, PA 17522

$2,075/Mo
Built 1951

Office space available for lease in Ephrata, Pennsylvania, suitable for professional services needing flexible workspace.

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Office Suite with Conference Room
Office Suite with Conference Room

114 East Main Street, Ephrata, PA 17522

Contact for pricing
10–16 people  2,500 sqft
4 private offices  1 meeting room

Four offices, a conference room, shared restrooms, and on-site parking serve this downtown workspace.

Onsite parking  Pylon sign  Shared bathrooms
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Office Space with High Traffic Exposure
Office Space with High Traffic Exposure

240 N 7th Suite 200, Ephrata, PA 17522

$1,595/Mo
Built 2000

Office space available for lease along a corridor with more than 20,000 vehicles daily.

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Restored Mansion Office Suites
Restored Mansion Office Suites

390 E Main St, Ephrata, PA 17522

Contact for pricing
1–2 people  1 space  423 sqft  Multi-tenant
Highway access

Historic mansion offices with elevator access and common area restrooms, offering multiple suite sizes for lease.

Elevator service  Common area restrooms
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Two-Level Office Space
Two-Level Office Space

1185 Division Hwy, Ephrata, PA 17522

Contact for pricing
80–133 people  20,048 sqft  Built 1979
Highway access + Road access  commercial

Commercially zoned space combines an open work area with private offices, meeting rooms, kitchenette, and restrooms.

Kitchenette
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Fully Fit-Out Office/Retail Suite
Fully Fit-Out Office/Retail Suite

108 N Reading Rd, Ephrata, PA 17522

Modified gross
Contact for pricing
1 space  Built 1955

Fully fit-out space in Cloister Shopping Center, positioned across from Ephrata Hospital along Rt 272.

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Retail Shopping Center Space
Retail Shopping Center Space

1759 West Main Street, Ephrata, PA 17522

Contact for pricing
Multi-tenant  8,246 sqft  62,000 GLA
12,000 VPD  Lancaster General Health, Two Cousins Pizza co-tenants

New construction retail center at a signalized intersection with up to 10,646 SF for additional retail or office.

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10 active listings match your search: Office for lease in Ephrata, PA. Based on your search, we've also compiled 7 Potential Opportunities for your consideration: 4 spaces in nearby cities and 3 properties for sale.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Freestanding Two-Story Office Building
Freestanding Two-Story Office Building

135 Rothsville Station Rd, Lititz, PA 17543

$1,700/Mo
6–11 people  1,664 sqft  Built 1960  2-story

Brick construction includes wood flooring, a full kitchen, and two bathrooms.

Full kitchen  2 bathrooms
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Office Units with Flexible Suite Options
Office Units with Flexible Suite Options

60 W Church Street C, Denver, PA 17517

$13,440/Mo
4–6 people  1,044 sqft  Built 1980

Two adjoining suites can be leased individually or together, with parking and practical support areas.

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Freestanding Office Building
Freestanding Office Building

130 S FOURTH Street, Denver, PA 17517

$625/Mo
Built 1940 / renov 2016
Highway access + Road access

Improvements completed in 2016 include exterior siding, a roof, and restroom updates; central air and off-street parking are provided.

3 parking spaces
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Office Unit with Walk-In Fireplace
Office Unit with Walk-In Fireplace

1398 E OREGON Road, Lititz, PA 17543

$596/Mo
1 space  510 sqft  Built 1890  0.53 acres
Highway access

Office space in a business center featuring a brick floor, walk-in fireplace, parking lot, and limited tenant-paid utilities.

16 parking spaces  Walk-in fireplace
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Similar Spaces for Sale in Ephrata, PA

Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

Move-In-Ready Office Unit
Move-In-Ready Office Unit

1656 W MAIN STREET, Ephrata, PA 17522

Contact for pricing
400 sqft

Utilities, Wi-Fi, and on-site parking support a simple move-in for business users.

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Multiroom Office Suite
Multiroom Office Suite

333 N STATE STREET #4, Ephrata, PA 17522

Contact for pricing
1,000 sqft

A flexible layout offers approximately three to four rooms for office, studio, or small-business use.

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Historic Office Building
Historic Office Building

390 E Main St, Ephrata, PA 17522

Contact for pricing
6,426 sqft

Flexible suites with individual entrances, elevator access, on-site parking, and preserved historic details.

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Ephrata, PA Office Spaces Lease Rates & Market Statistics

Browse 10 Office Spaces for lease in Ephrata, PA on Realmo, a commercial real estate marketplace serving the Ephrata area. The current inventory totals 31,217 square feet of properties — an average of ~3,100 SF per listing.

Asking lease rates for Office Spaces in Ephrata start at $1,400/Mo, average $3,057/Mo, and reach $8,223/Mo at the top of the market. That's a 6x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential.

Ephrata accounts for 4% of the 236 office spaces currently available across Lancaster County, where nearby markets include Lancaster and East Petersburg.

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