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Desoto County, MS Office Properties & Spaces for Lease

27 results
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Southaven Commercial Space For Lease
$2,200 / Mo
2,905 SF

Southaven Commercial Space For Lease

9127 Corporate Dr, Southaven, MS 38671

Office and warehouse space available for lease in Southaven.

  • Two warehouses: 600 sq ft (with storage room) and 1240 sq ft (separate entry)
  • Includes front lobby, 3 offices, common area, and 2 bathrooms
  • Zoned C4
  • Parking available in front of the building
  • Heating: Natural Gas, Central
Updated: Oct 11, 2025
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New Commercial Space in Olive Branch
$2,000 / Mo
7,344 SF

New Commercial Space in Olive Branch

7550 Alexander Rd Lot Bay, Olive Branch, MS 38654

Modern commercial space ideal for retail, office, or service businesses.

  • Brand‑new 1,200 sq. ft. commercial space in a growing area of Olive Branch.
  • Versatile unit suitable for retail, office, or service‑based businesses.
  • Open layout ready for customization.
  • Ample parking and excellent visibility.
  • Affordable rent of $2,000 per month (or $2,200 for Goodman Road facing bay).
Updated: Dec 3, 2025
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New Commercial Space in Olive Branch
$2,200 / Mo
7,344 SF

New Commercial Space in Olive Branch

Modern commercial space ideal for retail, office, or service businesses.

7550 Alexander Rd Lot Bay, Olive Branch, MS 38654
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New Commercial Space in Olive Branch
$2,000 / Mo
7,344 SF

New Commercial Space in Olive Branch

Modern commercial space ideal for retail, office, or service businesses.

7550 Alexander Rd, Olive Branch, MS 38654
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Olive Branch Commercial Space Available
$3,150 / Mo
1,260 SF

Olive Branch Commercial Space Available

1,260 SF commercial space in high-traffic Olive Branch location.

10680 Goodman Rd, Olive Branch, MS 38654
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Prime Olive Branch Office Space
$38 SF/Yr
5,129 SF

Prime Olive Branch Office Space

Class A Office Suites Available Now

6812 Crumpler Blvd, Olive Branch, MS 38654
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Southaven Towne Center Retail Space
Contact for pricing
567,640 SF

Southaven Towne Center Retail Space

Prime MS Retail Center, 567K SF

6474 Towne Center Loop, Southaven, MS 38671
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Olive Branch Retail Center
Contact for pricing
18,827 SF

Olive Branch Retail Center

High-traffic retail space in Olive Branch, MS

5036 Goodman Rd, Olive Branch, MS 38654
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Desoto Plaza: Medical Office Space
$7 SF/Yr
18,400 SF

Desoto Plaza: Medical Office Space

Main Street Southaven Medical Offices

1219 Main St, Southaven, MS 38671
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Southaven Retail/Office Space For Lease
$18 SF/Yr
2,400 SF

Southaven Retail/Office Space For Lease

Prime Southaven location, two units available.

8936 Airways Blvd, Southaven, MS 38671
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Hernando Square Executive Office Suites
$33 SF/Yr
540 SF

Hernando Square Executive Office Suites

Prestigious Hernando, MS office space available.

2555 Caffey St, Hernando, MS 38632
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Medical Office Park Near I-55
$19 SF/Yr
1,206 SF

Medical Office Park Near I-55

Medical office space for lease near Baptist DeSoto Hospital.

7900 Airways Blvd, Southaven, MS 38671
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Southaven Office/Retail Space For Lease
Contact for pricing
2,133 SF

Southaven Office/Retail Space For Lease

2,133 SF space in a popular mixed-use center.

5960 Getwell Rd, Southaven, MS 38672
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Southaven Medical Office Building
$775,000
3,152 SF

Southaven Medical Office Building

3,152 SF building ideal for office or medical use.

7732 Airways Blvd, Southaven, MS 38671
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Hernando Office Space For Rent
$21 SF/Yr
1,050 SF

Hernando Office Space For Rent

Office space available in Hernando, Mississippi, approximately 1,050 square feet.

2575 Caffey St, Hernando, MS 38632
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Premier Office Space in Olive Branch
$399,000
2,690 SF

Premier Office Space in Olive Branch

Modern office space with flexible floor plans in Olive Branch.

8136 Industrial Dr, Olive Branch, MS 38654
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Office Space on Goodman Road
$28 SF/Yr
1,500 SF

Office Space on Goodman Road

Office space for rent in a high-traffic location.

892 Goodman Rd E, Southaven, MS 38671
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Hernando Medical Office Space
$20 SF/Yr
4,608 SF

Hernando Medical Office Space

Medical office space in the heart of Hernando.

124 W Commerce St, Hernando, MS 38632
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Southaven Office and Retail Space
$22 SF/Yr
1,056 SF

Southaven Office and Retail Space

Office and retail space in the heart of Southaven.

232 Goodman Rd, Southaven, MS 38671
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Southaven Office Space For Lease
$12 SF/Yr
3,811 SF

Southaven Office Space For Lease

Office space available in Southaven, Mississippi, featuring small offices.

7145 Swinnea Rd, Southaven, MS 38671
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Modern Office Space Available
$11 SF/Yr
2,524 SF

Modern Office Space Available

Efficient office spaces with utilities included and ample parking.

2018 Mcingvale Rd, Hernando, MS 38632
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Southaven Office Space Available
Contact for pricing
5,500 SF

Southaven Office Space Available

Office space available for rent in Southaven, Mississippi.

5740 Getwell Rd, Southaven, MS 38672
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Modern Office Space in Olive Branch
$12 SF/Yr
8,065 SF

Modern Office Space in Olive Branch

Premier office space with customizable floor plans and modern amenities.

8804 Caroma St, Olive Branch, MS 38654
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Olive Branch Retail/Office Space
Contact for pricing

Olive Branch Retail/Office Space

Retail and office spaces available for lease in Olive Branch.

8963 Highway 178, Olive Branch, MS 38654
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Desoto County, MS Office Properties & Spaces Leasing Opportunities Market Analysis

Explore Office Properties & Spaces leasing options in Desoto County, MS with 36 listings featured on our commercial real estate exchange. The current inventory includes 3,985,130,160 square feet of properties with an estimated lease value of $309 /Mo.

Estimated lease rates for Office Properties & Spaces in Desoto County, MS begin at $3 SF/Yr, with an average of $17 SF/Yr and extend to $38 SF/Yr.
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