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    Desoto County, MS Office Spaces for Lease

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    Jackson, MS Ridgeland, MS Hattiesburg, MS
    32 results
    Olive Branch Commercial Space Available
    $3,150/Mo
    1,260 SF
    Olive Branch Commercial Space Available

    10680 Goodman Road, Olive Branch, MS 38654

    1,260 SF commercial space in high-traffic Olive Branch location.
    • High‑traffic location with an AADT of 34,000, providing excellent exposure.
    • 1,260 SF of flexible commercial space suitable for retail, office, or service‑oriented businesses.
    • Ample parking available for both customers and staff.
    • Convenient access to major roadways and nearby retail centers.
    • Zoned for a variety of commercial uses.
    Updated: Aug 15, 2025
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    Prime Retail/Office Space Available
    Contact for pricing
    1,200 SF
    Prime Retail/Office Space Available

    521 Stateline Road, Southaven, MS 38671

    Turn-key office space near major tenants, high visibility location.
    • Prime 1,200 SF turn key office space ready for immediate occupancy.
    • High‑traffic location with close proximity to major tenants Kroger and It's Fashion Metro.
    • Excellent visibility and accessibility at the prominent intersection of Stateline Road West and Hamilton Road.
    • Strategically positioned east of I‑55.
    • Located just 13 miles south of Memphis, Tennessee.
    Updated: Apr 1
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    Medical Office Park Near I-55
    $19 SF/Yr
    1,206 SF
    Medical Office Park Near I-55

    Medical office space for lease near Baptist DeSoto Hospital.

    7900 Airways Boulevard, Southaven, MS 38671

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    Modern Office Space in Olive Branch
    $12 SF/Yr
    Modern Office Space in Olive Branch

    Premier office property with customizable floor plans and modern amenities.

    8804 Caroma Street, Olive Branch, MS 38654

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    Customizable Commercial Space Available
    Contact for pricing
    6,000 SF
    Customizable Commercial Space Available

    6,000 +/- SF customizable space for rent.

    1177 Nesbit Drive, Nesbit, MS 38651

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    Hernando Office/Retail Leasing Opportunity
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    Hernando Office/Retail Leasing Opportunity

    Unique office/retail spaces near Hernando Square with recent renovations.

    2400 Highway 51 South, Hernando, MS 38632

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    Hernando Commercial Spaces For Lease
    Contact for pricing
    Hernando Commercial Spaces For Lease

    Accessible Hernando location with flexible office, service, or commercial spaces.

    3450 McCracken Road, Hernando, MS 38632

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    Southaven Flex Space For Rent
    $15 SF/Yr
    15,000 SF
    Southaven Flex Space For Rent

    15,000 SF flex space available for lease.

    7168 Moore Dr, Southaven, MS

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    Olive Branch Warehouse Space Available
    Contact for pricing
    60,000 SF
    Olive Branch Warehouse Space Available

    60,000 SF warehouse space with office in Olive Branch.

    8735 Nail Road, Olive Branch, MS 38654

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    Retail Single Tenant Space
    $180 SF/Yr
    2,537 SF
    Retail Single Tenant Space

    Retail space available for rent, approximately 2,537 square feet.

    8101 Hacks Cross Rd, Olive Branch, MS 38654

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    Horn Lake Office/Retail Suites
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    1,800 SF
    Horn Lake Office/Retail Suites

    Flexible suites for office or retail use in Horn Lake.

    1751 Dancy Blvd, Horn Lake, MS 38637

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    Retail/Office Space in Southaven
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    Retail/Office Space in Southaven

    Located in a recognizable area with high visibility and access.

    2855 Nail Rd E, Southaven, MS 38672

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    Southaven Office/Retail Space For Lease
    Contact for pricing
    2,133 SF
    Southaven Office/Retail Space For Lease

    2,133 SF space in a popular mixed-use center.

    5960 Getwell Rd, Southaven, MS

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    Southaven Office Space Available
    Contact for pricing
    5,500 SF
    Southaven Office Space Available

    Office space available for rent in Southaven, Mississippi.

    5740 Getwell Road, Southaven, MS 38672

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    Updated Office Building For Rent
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    Updated Office Building For Rent

    Renovated Class B office building in Olive Branch, Mississippi.

    6933 Crumpler Blvd., Olive Branch, MS 38654

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    Versatile Flex Suite For Rent
    Contact for pricing
    1,250 SF
    Versatile Flex Suite For Rent

    Flex suite with office and warehouse space, convenient location.

    889 Nesbit Road, Nesbit, MS 38651

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    Hernando Industrial Cove Lease Opportunity
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    7,500 SF
    Hernando Industrial Cove Lease Opportunity

    Lease up to 7,500 SF in Hernando Industrial Cove.

    3071 Industrial Drive W, Hernando, MS 38632

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    Southaven Office and Retail Space
    $22 SF/Yr
    1,056 SF
    Southaven Office and Retail Space

    Office and retail space in the heart of Southaven.

    232 Goodman Rd, Southaven, MS

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    Renovated Retail or Office Space
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    Renovated Retail or Office Space

    Located off Hernando Square, ideal for retail or office use.

    2425 East Street, Hernando, MS 38632

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    Office Space in Olive Branch
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    1,172 SF
    Office Space in Olive Branch

    Office space with private offices, reception, and break room.

    6943 Oak Forest Drive, Olive Branch, MS 38654

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    Office Space on Goodman Road
    $28 SF/Yr
    1,500 SF
    Office Space on Goodman Road

    Office space for rent in a high-traffic location.

    892 Goodman Rd E, Southaven, MS

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    Modern Office Space Available
    $11 SF/Yr
    2,524 SF
    Modern Office Space Available

    Efficient office spaces with utilities included and ample parking.

    2018 Mcingvale Rd, Hernando, MS

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    Hernando Office Space For Rent
    $21 SF/Yr
    1,050 SF
    Hernando Office Space For Rent

    Office space available in Hernando, Mississippi, approximately 1,050 square feet.

    2575 Caffey St, Hernando, MS

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    Hernando Medical Office Space
    $20 SF/Yr
    4,608 SF
    Hernando Medical Office Space

    Medical office space in the heart of Hernando.

    124 W Commerce St, Hernando, MS

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    Desoto County, MS Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Desoto County, MS with 32 listings featured on our commercial real estate exchange. The current inventory includes 34,741 square feet of properties with an estimated lease value of $369 /Mo.

    Estimated lease rates for Office Spaces in Desoto County, MS begin at $9 SF/Yr, with an average of $33 SF/Yr and extend to $180 SF/Yr.
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    Browse Office Spaces for Lease Near Desoto, MS

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