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Desoto County, MS Office Properties & Spaces for Lease

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36 results
New Commercial Space in Olive Branch
$2,000 /Mo
7,344 SF

New Commercial Space in Olive Branch

7550 Alexander Road, Olive Branch, MS 38654

Modern commercial space ideal for retail, office, or service businesses.

  • Brand‑new 1,200 sq. ft. commercial space.
  • Located in a growing area of Olive Branch.
  • Versatile unit ideal for retail, office, or service‑based businesses.
  • Open layout ready for customization.
  • Ample parking and excellent visibility.
Updated: Dec 1, 2025
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Olive Branch Commercial Space Available
$3,150 /Mo
1,260 SF

Olive Branch Commercial Space Available

10680 Goodman Road, Olive Branch, MS 38654

1,260 SF commercial space in high-traffic Olive Branch location.

  • High‑traffic location with an AADT of 34,000, providing excellent exposure.
  • 1,260 SF of flexible commercial space suitable for retail, office, or service‑oriented businesses.
  • Ample parking available for both customers and staff.
  • Convenient access to major roadways and nearby retail centers.
  • Zoned for a variety of commercial uses.
Updated: Aug 15, 2025
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New Commercial Space in Olive Branch
$2,000 /Mo
7,344 SF

New Commercial Space in Olive Branch

Modern commercial space ideal for retail, office, or service businesses.

7550 Alexander Road lot: Bay 2, Olive Branch, MS 38654
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New Commercial Space in Olive Branch
$2,200 /Mo
7,344 SF

New Commercial Space in Olive Branch

Modern commercial space ideal for retail, office, or service businesses.

7550 Alexander Road lot: Bay 3, Olive Branch, MS 38654
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Modern Office Space in Olive Branch
$12 SF/Yr

Modern Office Space in Olive Branch

Premier office property with customizable floor plans and modern amenities.

8804 Caroma Street, Olive Branch, MS 38654
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Hernando Commercial Spaces For Lease
Contact for pricing

Hernando Commercial Spaces For Lease

Accessible Hernando location with flexible office, service, or commercial spaces.

3450 McCracken Road, Hernando, MS 38632
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Customizable Commercial Space Available
Contact for pricing
6,000 SF

Customizable Commercial Space Available

6,000 +/- SF customizable space for rent.

1177 Nesbit Drive, Nesbit, MS 38651
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Hernando Office/Retail Leasing Opportunity
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Hernando Office/Retail Leasing Opportunity

Unique office/retail spaces near Hernando Square with recent renovations.

2400 Highway 51 South, Hernando, MS 38632
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Southaven Flex Space For Rent
$15 SF/Yr
15,000 SF

Southaven Flex Space For Rent

15,000 SF flex space available for lease.

7168 Moore Dr, Southaven, MS
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Medical Office Park Near I-55
$19 SF/Yr
1,206 SF

Medical Office Park Near I-55

Medical office space for lease near Baptist DeSoto Hospital.

7900 Airways Boulevard, Southaven, MS 38671
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Southaven Office/Retail Space For Lease
Contact for pricing
2,133 SF

Southaven Office/Retail Space For Lease

2,133 SF space in a popular mixed-use center.

5960 Getwell Rd, Southaven, MS
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Olive Branch Warehouse Space Available
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60,000 SF

Olive Branch Warehouse Space Available

60,000 SF warehouse space with office in Olive Branch.

8735 Nail Road, Olive Branch, MS 38654
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Retail Single Tenant Space
$180 SF/Yr
2,537 SF

Retail Single Tenant Space

Retail space available for rent, approximately 2,537 square feet.

8101 Hacks Cross Rd, Olive Branch, MS 38654
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Horn Lake Office/Retail Suites
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1,800 SF

Horn Lake Office/Retail Suites

Flexible suites for office or retail use in Horn Lake.

1751 Dancy Blvd, Horn Lake, MS 38637
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Updated Office Building For Rent
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Updated Office Building For Rent

Renovated Class B office building in Olive Branch, Mississippi.

6933 Crumpler Blvd., Olive Branch, MS 38654
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Southaven Office Space Available
Contact for pricing
5,500 SF

Southaven Office Space Available

Office space available for rent in Southaven, Mississippi.

5740 Getwell Road, Southaven, MS 38672
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Retail/Office Space in Southaven
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Retail/Office Space in Southaven

Located in a recognizable area with high visibility and access.

2855 Nail Rd E, Southaven, MS 38672
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Hernando Industrial Cove Lease Opportunity
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7,500 SF

Hernando Industrial Cove Lease Opportunity

Lease up to 7,500 SF in Hernando Industrial Cove.

3071 Industrial Drive W, Hernando, MS 38632
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Renovated Retail or Office Space
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Renovated Retail or Office Space

Located off Hernando Square, ideal for retail or office use.

2425 East Street, Hernando, MS 38632
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Office Space in Olive Branch
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1,172 SF

Office Space in Olive Branch

Office space with private offices, reception, and break room.

6943 Oak Forest Drive, Olive Branch, MS 38654
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Modern Office Space Available
$11 SF/Yr
2,524 SF

Modern Office Space Available

Efficient office spaces with utilities included and ample parking.

2018 Mcingvale Rd, Hernando, MS
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Hernando Medical Office Space
$20 SF/Yr
4,608 SF

Hernando Medical Office Space

Medical office space in the heart of Hernando.

124 W Commerce St, Hernando, MS
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Warehouse/Office Space For Lease
Contact for pricing

Warehouse/Office Space For Lease

Ideal warehouse/office space with high visibility and accessibility.

7074 302 Industrial Drive, Southaven, MS 38671
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Southaven Office and Retail Space
$22 SF/Yr
1,056 SF

Southaven Office and Retail Space

Office and retail space in the heart of Southaven.

232 Goodman Rd, Southaven, MS
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Desoto County, MS Office properties & Spaces Leasing Opportunities Market Analysis

Explore Office properties & Spaces leasing options in Desoto County, MS with 36 listings featured on our commercial real estate exchange. The current inventory includes 2,292,824,160 square feet of properties with an estimated lease value of $197 SF/Yr.

Estimated lease rates for Office properties & Spaces in Desoto County, MS begin at $3 SF/Yr, with an average of $16 SF/Yr and extend to $30 SF/Yr.
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