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    Desoto County, MS Commercial Real Estate for Sale

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    Gulfport, MS Jackson, MS Hattiesburg, MS
    164 results
    Established Car Wash Business Opportunity
    $550,000
    3,663 SF
    Established Car Wash Business Opportunity

    2934 S Hwy 51, Hernando, MS 38632

    Turnkey car wash business for sale in prime location.
    • Prime location with 165 feet of highway frontage on Highway 51 South, near Hernando town square.
    • Turnkey car wash business established since 2007 with a loyal customer base.
    • Spacious 1.1‑acre lot with 18,000 square feet of concrete.
    • Six self‑serve combo brush/spray bays and an automatic car wash.
    • Zoned Commercial C2, allowing for alternative uses.
    Updated: Mar 1
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    Former Bank Building on Goodman
    $799,000
    2,786 SF
    Former Bank Building on Goodman

    2304 Goodman Road, Horn Lake, MS 38637

    2786 SF commercial building with drive-thru and ample parking.
    • High‑traffic location on Goodman Road with excellent visibility and convenient access to I‑55 and I‑69.
    • Turnkey former bank building (2786 sf) with existing infrastructure: teller stations, drive‑thru, offices, and security system.
    • Ample parking with 30 spaces and a 5‑lane drive‑thru.
    • Security features including interior/exterior cameras, security system, and existing safe.
    • Functional layout including multiple offices, workstations, break room, and restrooms.
    Updated: Jan 14
    View details
    Modern Gas Station and Store
    $3,500,000
    5,570 SF
    Modern Gas Station and Store

    High-performing gas station and convenience store in Olive Branch, MS.

    7641 Hacks Cross Road, Olive Branch, MS 38654

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    Turnkey Car Wash Business Opportunity
    $250,000
    1,840 SF
    Turnkey Car Wash Business Opportunity

    Established car wash business in Lake Cormorant, MS for sale.

    1999 Highway 301 S, Lake Cormorant, MS 38641

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    Hernando Commercial Business Opportunity
    $400,000
    1,800 SF
    Hernando Commercial Business Opportunity

    Commercial property in the heart of Hernando, zoned C2.

    310 E S Street, Hernando, MS 38632

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    Southaven, MS Commercial Development Opportunity
    $449,500
    3.10 Acres
    Southaven, MS Commercial Development Opportunity

    3.10 acres of commercial land in growing Southaven, MS.

    Airways Boulevard lot: 3, Southaven, MS 38671

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    Southaven Commercial Property For Sale
    $999,990
    5,000 SF
    Southaven Commercial Property For Sale

    Two office buildings on 1.2 acres in high-demand area.

    5185 Getwell Road lot: 5187, Southaven, MS 38672

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    Southaven Commercial Lot Investment Opportunity
    $650,000
    3.78 Acres
    Southaven Commercial Lot Investment Opportunity

    3.8 acre commercial lot on Goodman Rd in Southaven, MS.

    38 E Goodman Road, Southaven, MS 38671

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    32 Acres Commercial Land
    $1,290,000
    32.00 Acres
    32 Acres Commercial Land

    32+/- acres with commercial potential in Lake Cormorant, MS.

    5000 Church Road, Lake Cormorant, MS 38641

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    Southaven Commercial Lot For Sale
    $150,000
    0.78 Acres
    Southaven Commercial Lot For Sale

    Commercial lot in Southaven, MS, near Getwell and Rasco Rd.

    403 Getwell Road lot: 403, Southaven, MS 38671

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    Southaven Commercial Property For Sale
    $160,000
    1,100 SF
    Southaven Commercial Property For Sale

    Commercial property with potential for various uses in Southaven, MS.

    55 E Stateline Road, Southaven, MS 38671

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    39.69 Acres in Hernando, MS
    $1,290,000
    39.69 Acres
    39.69 Acres in Hernando, MS

    Prime real estate in Lewisburg School District with pastureland.

    4461 Hwy 305 S, Hernando, MS 38632

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    Southaven Corner Lot Opportunity
    $195,000
    0.87 Acres
    Southaven Corner Lot Opportunity

    Corner lot in Southaven, ideal for professional office.

    401 Getwell Road lot: 401, Southaven, MS 38671

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    Commercial Land with Log Cabin
    $750,000
    5.32 Acres
    Commercial Land with Log Cabin

    C4-zoned commercial site with long road frontage and an as-is log home that may suit a small office.

    771 W Church Road, Southaven, MS 38671

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    Zoned Office Development Land
    $120,000
    0.74 Acres
    Zoned Office Development Land

    A 0.74+/- acre lot zoned for office use near a high-visibility Hwy 305 and Old Goodman Rd intersection.

    Westbranch Road lot: 23, Olive Branch, MS 38654

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    Diverse Acreage with Delta Views
    $4,336,880
    542.11 Acres
    Diverse Acreage with Delta Views

    542-acre property near Memphis with diverse terrain and recreational opportunities.

    4591 Delta View, Walls, MS 38680

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    Southaven Commercial Corner Office Lot
    $295,000
    0.78 Acres
    Southaven Commercial Corner Office Lot

    Corner lot in medical district, utilities available, near hospital.

    78 Clarington Cove lot: 17, Southaven, MS 38671

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    Horn Lake Commercial Land Opportunity
    $315,000
    2,913 SF
    Horn Lake Commercial Land Opportunity

    Prime commercial land with potential office conversion in Horn Lake.

    6501 U.S. 51, Horn Lake, MS 38637

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    Horn Lake Commercial Land Available
    $530,000
    435,600 SF
    Horn Lake Commercial Land Available

    Cleared, level land suitable for commercial development in Horn Lake.

    Highway 51, Horn Lake, MS 38637

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    Southaven Commercial Land For Sale
    $1,450,000
    5.95 Acres
    Southaven Commercial Land For Sale

    Located in the medical district with multi-family retail approval.

    N Airways Boulevard lot: 2-3, Southaven, MS 38671

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    Southaven Commercial Development Opportunity
    $1,200,000
    9.00 Acres
    Southaven Commercial Development Opportunity

    9 acres in Southaven, MS, prime for commercial development.

    9 Marathon Way lot: 7E, Southaven, MS 38671

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    Versatile Commercial Property in Nesbit
    $1,300,000
    5,900 SF
    Versatile Commercial Property in Nesbit

    Office and industrial space with C-2 zoning.

    434 Nesbit Rd, Nesbit, MS 38651

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    Ready-to-Build Land in Hernando, MS
    $158,000
    4.62 Acres
    Ready-to-Build Land in Hernando, MS

    4.62 acre lot in Lewisburg School District.

    8600 County Line Road, Hernando, MS 38632

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    Commercial Site in Olive Branch
    $185,000
    3,400 SF
    Commercial Site in Olive Branch

    Commercial site with building on Highway 178 and Maywood.

    8205 Highway 178, Olive Branch, MS 38654

    View details

    Desoto County, MS Commercial Real Estate Investment Opportunities Market Analysis

    Explore 164 commercial real estate for sale in Desoto County, MS, showcased through 164 active listings on our real estate platform. These investment opportunities span a total of 718,162 square feet of properties for sale, with an estimated market value of $38,582,649.

    Sale prices for business properties in Desoto County, MS start at $160,000, averaging $1,483,948, and reaching up to $8,665,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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