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    La Mesa, CA Commercial Real Estate for Lease

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    Renovated Office Space in La Mesa
    Updated: Mar 10
    Renovated Office Space in La Mesa

    9633 Grossmont Summit Dr., La Mesa, CA 91941

    $1,000/Mo
    2,000 sqft
    Excellent freeway access and visibility from I‑8.
    Move‑in ready, beautifully renovated office space.
    Flexible workspace: approximately 1,300 - 2,000 divisible square feet.
    Located in a central, professional area near Mt. Helix in La Mesa.
    Includes air conditioning and a private bathroom.
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    Boutique Medical Office Space
    Updated: Nov 25, 2025
    Boutique Medical Office Space

    5200 Lake Murray Blvd, La Mesa, CA

    $6.02 SF/Yr
    900 sqft
    Prime location at a signalized intersection with I‑8 Freeway on‑ramp access.
    Close proximity to major hospitals: Sharp Grossmont and UC San Diego Health East Campus Medical Center.
    Turnkey medical office space with pristine finishes and high‑end aesthetics.
    Newly renovated with fresh paint, new LED lighting, and new tile flooring.
    Boutique medical office setting.
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    Retail Space For Lease
    Retail Space For Lease

    6055-6063 Lake Murray Blvd, La Mesa, CA

    $19.80 SF/Yr
    1,358 sqft

    Retail space available for lease.

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    La Mesa Retail Space Available
    La Mesa Retail Space Available

    8310-8312 La Mesa Blvd, La Mesa, CA

    $30 SF/Yr
    5,000 sqft

    Retail space available for rent in La Mesa, CA.

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    La Mesa Office/Retail Building
    La Mesa Office/Retail Building

    8415 La Mesa Blvd, La Mesa, CA

    $23.04 SF/Yr
    5,942 sqft

    Office/retail building available for sale in La Mesa, CA.

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    Plug-and-Play Office Suite
    Plug-and-Play Office Suite

    9019 Park Plaza Dr, La Mesa, CA 91942

    Contact for pricing
    462 sqft

    Modern office suite with a private office, open workspace, and an in-suite restroom for immediate occupancy.

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    La Mesa Retail Space Available
    La Mesa Retail Space Available

    9089 Dallas St, La Mesa, CA

    Contact for pricing
    7,000 sqft

    Retail space in La Mesa with high traffic counts.

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    La Mesa Office Space Available
    La Mesa Office Space Available

    8911 La Mesa Blvd, La Mesa, CA

    Contact for pricing
    1,100 sqft

    Office space available for rent in La Mesa, California.

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    La Mesa Office Space Available
    La Mesa Office Space Available

    7373 University Ave, La Mesa, CA

    Contact for pricing
    2,058 sqft

    Office space for rent in La Mesa, California.

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    Furnished Private Office Suite
    Furnished Private Office Suite

    4752 Palm Avenue, La Mesa, CA 91942

    Contact for pricing

    Move-in-ready furnished office with a private entrance, suited for small professional teams needing space for up to three desks.

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    La Mesa Office/Warehouse Building
    La Mesa Office/Warehouse Building

    8384 Hercules St, La Mesa, CA

    $19,750/Mo
    4,000 sqft

    4,000 SF office/warehouse with high-end improvements and fenced lot.

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    La Mesa Super Regional Center
    La Mesa Super Regional Center

    5500 Grossmont Center Dr, La Mesa, CA

    Contact for pricing
    55,000 sqft

    925,000 SF shopping center in La Mesa, California.

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    La Mesa Retail/Medical Space
    La Mesa Retail/Medical Space

    8702-8716 La Mesa Blvd, La Mesa, CA

    Contact for pricing
    1,342 sqft

    Retail or medical space featuring treatment rooms and reception area.

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    La Mesa Retail Space Available
    La Mesa Retail Space Available

    6101-6179 Lake Murray Blvd, La Mesa, CA

    Contact for pricing
    23,256 sqft

    In-line retail space available for lease in La Mesa.

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    La Mesa Office Property
    La Mesa Office Property

    5400 Connecticut Ave, La Mesa, CA

    $5.46 SF/Yr

    Fully leased office property in La Mesa, California.

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    La Mesa Office Space Available
    La Mesa Office Space Available

    5565 Grossmont Center Dr, La Mesa, CA

    Contact for pricing
    2,524 sqft

    Office space for rent near Sharp Grossmont Hospital.

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    Visible Retail Space, Freeway Access
    Visible Retail Space, Freeway Access

    5232 Jackson Drive, La Mesa, CA 91942

    Contact for pricing

    Highly visible retail space with freeway access and strong co-tenancy.

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    La Mesa Retail Space Available
    La Mesa Retail Space Available

    7900-7938 El Cajon Blvd, La Mesa, CA

    Contact for pricing
    19,262 sqft

    Retail space with high visibility and immediate highway access.

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    La Mesa Retail Space Available
    La Mesa Retail Space Available

    5630-5650 Lake Murray Blvd, La Mesa, CA

    Contact for pricing
    1,400 sqft

    Retail space available for lease in La Mesa, CA.

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    La Mesa Retail/Office Space
    La Mesa Retail/Office Space

    5276-5282 Baltimore Dr, La Mesa, CA

    Contact for pricing
    1,500 sqft

    Retail or office space featuring an open floor plan.

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    Retail Showroom and Warehouse Space
    Retail Showroom and Warehouse Space

    7575 University Ave, La Mesa, CA 91942

    $15,269/Mo

    Retail showroom and warehouse with easy freeway access available for lease.

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    Retail Space in La Mesa
    Retail Space in La Mesa

    8825 Murray Dr, La Mesa, CA

    Contact for pricing
    4,555 sqft

    Retail property available for lease in La Mesa, California.

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    La Mesa Retail Space
    La Mesa Retail Space

    5475 Grossmont Center Dr, La Mesa, CA

    $42 SF/Yr
    5,000 sqft

    Retail space available for lease in La Mesa, California.

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    La Mesa Multi-Tenant Office
    La Mesa Multi-Tenant Office

    7484 University Ave, La Mesa, CA

    Contact for pricing
    873 sqft

    Multi-tenant office building in La Mesa with ample parking.

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    La Mesa, CA Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in La Mesa, CA with 37 listings featured on our commercial real estate exchange. The current inventory includes 30,731 square feet of properties with an estimated lease value of $237.36 SF/Yr.

    Estimated lease rates for Commercial real estate in La Mesa, CA begin at $1.15 SF/Yr, with an average of $21.58 SF/Yr and extend to $59.25 SF/Yr.
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    Most Searched ZIP Codes in La Mesa, CA

    • 91942
    • 91941

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