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    La Mesa, CA Commercial Real Estate for Lease

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    Los Angeles, CA San Diego, CA San Francisco, CA
    42 results
    Boutique Medical Office Space
    $6 SF/Yr
    900 SF

    Boutique Medical Office Space

    5200 Lake Murray Blvd, La Mesa, CA

    Medical office space with pristine finishes and high-end aesthetics.

    • Prime location at a signalized intersection with I‑8 Freeway on‑ramp access.
    • Close proximity to major hospitals: Sharp Grossmont and UC San Diego Health East Campus Medical Center.
    • Turnkey medical office space with pristine finishes and high‑end aesthetics.
    • Newly renovated with fresh paint, new LED lighting, and new tile flooring.
    • Boutique medical office setting.
    Updated: Nov 25, 2025
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    Turn-Key Office Suites Available
    $2 SF/Yr

    Turn-Key Office Suites Available

    3855 Avocado Blvd, La Mesa, CA

    Turn-key office suites with shared reception and waiting area.

    • Turn‑key office suites ready for immediate occupancy.
    • Short term leases available, offering flexibility.
    • Shared reception and waiting area.
    • Executive suites available.
    • $500/month rental price.
    Updated: Nov 24, 2025
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    La Mesa Retail Space Available
    $30 SF/Yr
    5,000 SF

    La Mesa Retail Space Available

    Retail space available for rent in La Mesa, CA.

    8310-8312 La Mesa Blvd, La Mesa, CA
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    La Mesa Office/Retail Building
    $23 SF/Yr
    5,942 SF

    La Mesa Office/Retail Building

    Office/retail building available for sale in La Mesa, CA.

    8415 La Mesa Blvd, La Mesa, CA
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    La Mesa Retail/Medical Space
    Contact for pricing
    1,342 SF

    La Mesa Retail/Medical Space

    Retail or medical space featuring treatment rooms and reception area.

    8702-8716 La Mesa Blvd, La Mesa, CA
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    Retail Space For Lease
    $19 SF/Yr
    1,358 SF

    Retail Space For Lease

    Retail space available for lease.

    6055-6063 Lake Murray Blvd, La Mesa, CA
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    Private Office in Historic Building
    $54 SF/Yr

    Private Office in Historic Building

    Private office space available for rent in historic building.

    8200 Allison Avenue, La Mesa, CA 91942
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    Retail/Office Space in La Mesa
    $24 SF/Yr
    1,800 SF

    Retail/Office Space in La Mesa

    Retail or office space with open floor plan available for rent.

    5260-5266 Baltimore Dr, La Mesa, CA
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    La Mesa Retail Space Available
    Contact for pricing
    1,200 SF

    La Mesa Retail Space Available

    Retail space available for lease in La Mesa, California.

    7966-8131 La Mesa Blvd, La Mesa, CA 91942
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    Retail Space in La Mesa
    Contact for pricing
    1,300 SF

    Retail Space in La Mesa

    Retail space available for lease in La Mesa, California.

    5200 JACKSON DR, La Mesa, CA
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    Retail Space in Mesa Plaza
    Contact for pricing

    Retail Space in Mesa Plaza

    Retail space with high visibility and strong tenant mix.

    7520 El Cajon Blvd, La Mesa, CA 91942
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    La Mesa Office Space Available
    $1.75 SF/Yr
    1,100 SF

    La Mesa Office Space Available

    Office space available for rent in La Mesa, California.

    8911 La Mesa Blvd, La Mesa, CA
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    La Mesa Retail Space Available
    Contact for pricing
    19,262 SF

    La Mesa Retail Space Available

    Retail space with high visibility and immediate highway access.

    7900-7938 El Cajon Blvd, La Mesa, CA
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    La Mesa Office Property
    Contact for pricing

    La Mesa Office Property

    Fully leased office property in La Mesa, California.

    5400 Connecticut Ave, La Mesa, CA
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    La Mesa Retail Space Available
    $24 SF/Yr
    1,800 SF

    La Mesa Retail Space Available

    Retail space available for lease in La Mesa, California.

    5286-5290 Baltimore Dr, La Mesa, CA
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    La Mesa Retail Space Available
    Contact for pricing
    7,000 SF

    La Mesa Retail Space Available

    Retail space in La Mesa with high traffic counts.

    9089 Dallas St, La Mesa, CA
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    La Mesa Office/Warehouse Building
    $19,750 /Mo
    4,000 SF

    La Mesa Office/Warehouse Building

    4,000 SF office/warehouse with high-end improvements and fenced lot.

    8384 Hercules St, La Mesa, CA
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    Fletcher Parkway Specialty Property
    Contact for pricing

    Fletcher Parkway Specialty Property

    Specialty property available for rent on Fletcher Parkway.

    8881 Fletcher Parkway, La Mesa, CA 91942
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    La Mesa Retail Space Available
    Contact for pricing
    1,400 SF

    La Mesa Retail Space Available

    Retail space available for lease in La Mesa, CA.

    5630-5650 Lake Murray Blvd, La Mesa, CA
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    La Mesa Retail/Office Space
    Contact for pricing
    1,500 SF

    La Mesa Retail/Office Space

    Retail or office space featuring an open floor plan.

    5276-5282 Baltimore Dr, La Mesa, CA
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    La Mesa Super Regional Center
    Contact for pricing
    55,000 SF

    La Mesa Super Regional Center

    925,000 SF shopping center in La Mesa, California.

    5500 Grossmont Center Dr, La Mesa, CA
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    La Mesa Multi-Tenant Office
    $1.15 SF/Yr
    873 SF

    La Mesa Multi-Tenant Office

    Multi-tenant office building in La Mesa with ample parking.

    7484 University Ave, La Mesa, CA
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    La Mesa Retail Space Available
    Contact for pricing
    23,256 SF

    La Mesa Retail Space Available

    In-line retail space available for lease in La Mesa.

    6101-6179 Lake Murray Blvd, La Mesa, CA
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    Retail Space in La Mesa
    Contact for pricing
    4,555 SF

    Retail Space in La Mesa

    Retail property available for lease in La Mesa, California.

    8825 Murray Dr, La Mesa, CA
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    La Mesa, CA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in La Mesa, CA with 42 listings featured on our commercial real estate exchange. The current inventory includes 6,449,842,080 square feet of properties with an estimated lease value of $0.00 SF/Yr.

    Estimated lease rates for Commercial real estate in La Mesa, CA begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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    Most Searched ZIP Codes in La Mesa, CA

    • 91942
    • 91941

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