La Mesa, CA
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    La Mesa, CA Commercial Real Estate for Lease

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    San Diego, CA Lemon Grove, CA Spring Valley, CA
    47 results
    Gateway Chula Vista
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    CA, Santee - Cuyamaca St
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    Private Office in Historic Building
    $650/Mo
    Private Office in Historic Building

    8200 Allison Ave, La Mesa, CA 91942

    Sublease private office with parking, utilities, and Wi-Fi.
    • Private office sublease in a historic building
    • Includes utilities, Wi‑Fi, and one parking space
    • High visibility location with potential for signage
    • Two windows that open for ventilation
    • Walking distance to restaurants, post office, and other amenities
    Updated: Apr 24
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    Boutique Medical Office Space
    $6 SF/Yr
    900 SF
    Boutique Medical Office Space

    5200 Lake Murray Blvd, La Mesa, CA

    Medical office space with pristine finishes and high-end aesthetics.
    • Prime location at a signalized intersection with I‑8 Freeway on‑ramp access.
    • Close proximity to major hospitals: Sharp Grossmont and UC San Diego Health East Campus Medical Center.
    • Turnkey medical office space with pristine finishes and high‑end aesthetics.
    • Newly renovated with fresh paint, new LED lighting, and new tile flooring.
    • Boutique medical office setting.
    Updated: Nov 25, 2025
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    La Mesa Office Space Available
    $2 SF/Yr
    2,058 SF
    La Mesa Office Space Available

    Office space for rent in La Mesa, California.

    7373 University Ave, La Mesa, CA

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    Turn-Key Office Suites Available
    $2 SF/Yr
    Turn-Key Office Suites Available

    Turn-key office suites with shared reception and waiting area.

    3855 Avocado Blvd, La Mesa, CA

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    Retail Space For Lease
    $19 SF/Yr
    1,358 SF
    Retail Space For Lease

    Retail space available for lease.

    6055-6063 Lake Murray Blvd, La Mesa, CA

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    La Mesa Retail Space Available
    $30 SF/Yr
    5,000 SF
    La Mesa Retail Space Available

    Retail space available for rent in La Mesa, CA.

    8310-8312 La Mesa Blvd, La Mesa, CA

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    Private Office in Historic Building
    $54 SF/Yr
    Private Office in Historic Building

    Private office space available for rent in historic building.

    8200 Allison Avenue, La Mesa, CA 91942

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    La Mesa Office/Retail Building
    $23 SF/Yr
    5,942 SF
    La Mesa Office/Retail Building

    Office/retail building available for sale in La Mesa, CA.

    8415 La Mesa Blvd, La Mesa, CA

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    Retail/Office Space in La Mesa
    $24 SF/Yr
    1,800 SF
    Retail/Office Space in La Mesa

    Retail or office space with open floor plan available for rent.

    5260-5266 Baltimore Dr, La Mesa, CA

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    La Mesa Retail Space Available
    $24 SF/Yr
    1,800 SF
    La Mesa Retail Space Available

    Retail space available for lease in La Mesa, California.

    5286-5290 Baltimore Dr, La Mesa, CA

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    La Mesa Office Property
    $5 SF/Yr
    La Mesa Office Property

    Fully leased office property in La Mesa, California.

    5400 Connecticut Ave, La Mesa, CA

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    Retail Space in La Mesa
    Contact for pricing
    1,300 SF
    Retail Space in La Mesa

    Retail space available for lease in La Mesa, California.

    5200 JACKSON DR, La Mesa, CA

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    Retail Space in Mesa Plaza
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    Retail Space in Mesa Plaza

    Retail space with high visibility and strong tenant mix.

    7520 El Cajon Blvd, La Mesa, CA 91942

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    La Mesa Office Space Available
    $1.75 SF/Yr
    1,100 SF
    La Mesa Office Space Available

    Office space available for rent in La Mesa, California.

    8911 La Mesa Blvd, La Mesa, CA

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    La Mesa Retail Space Available
    Contact for pricing
    1,200 SF
    La Mesa Retail Space Available

    Retail space available for lease in La Mesa, California.

    7966-8131 La Mesa Blvd, La Mesa, CA 91942

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    La Mesa Office/Warehouse Building
    $19,750/Mo
    4,000 SF
    La Mesa Office/Warehouse Building

    4,000 SF office/warehouse with high-end improvements and fenced lot.

    8384 Hercules St, La Mesa, CA

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    La Mesa Super Regional Center
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    55,000 SF
    La Mesa Super Regional Center

    925,000 SF shopping center in La Mesa, California.

    5500 Grossmont Center Dr, La Mesa, CA

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    La Mesa Retail/Medical Space
    Contact for pricing
    1,342 SF
    La Mesa Retail/Medical Space

    Retail or medical space featuring treatment rooms and reception area.

    8702-8716 La Mesa Blvd, La Mesa, CA

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    La Mesa Retail Space Available
    Contact for pricing
    23,256 SF
    La Mesa Retail Space Available

    In-line retail space available for lease in La Mesa.

    6101-6179 Lake Murray Blvd, La Mesa, CA

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    La Mesa Multi-Tenant Office
    $1.15 SF/Yr
    873 SF
    La Mesa Multi-Tenant Office

    Multi-tenant office building in La Mesa with ample parking.

    7484 University Ave, La Mesa, CA

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    La Mesa Retail Space Available
    Contact for pricing
    19,262 SF
    La Mesa Retail Space Available

    Retail space with high visibility and immediate highway access.

    7900-7938 El Cajon Blvd, La Mesa, CA

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    Visible Retail Space, Freeway Access
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    Visible Retail Space, Freeway Access

    Highly visible retail space with freeway access and strong co-tenancy.

    5232 Jackson Drive, La Mesa, CA 91942

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    La Mesa, CA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in La Mesa, CA with 47 listings featured on our commercial real estate exchange. The current inventory includes 31,150 square feet of properties with an estimated lease value of $346 /Mo.

    Estimated lease rates for Commercial real estate in La Mesa, CA begin at $1.15 SF/Yr, with an average of $23 SF/Yr and extend to $59 SF/Yr.
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