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Sanford, ME Mixed-use Properties for Sale

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Mixed-Use Investment Opportunity
$499,900
4,048 SF

Mixed-Use Investment Opportunity

446 Main St, Sanford, ME 04083

Mixed-use property with commercial space and apartments in downtown Sanford.

  • Fully leased commercial space (restaurant) provides strong, steady income.
  • Two fully rented, spacious 3‑bedroom apartments generate additional reliable revenue.
  • Prime mixed‑use investment opportunity in downtown Springvale, ME.
  • High‑visibility location in a thriving downtown setting.
  • Turnkey asset with a stable tenant base.
Updated: Nov 21, 2025
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Based on your search, we've compiled 108 Potential Opportunities for your consideration. Besides 1 Active listings in Sanford, ME, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 102 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Prime Milton Campground - Development Opportunity
$1,800,000
236,095 SF

Prime Milton Campground - Development Opportunity

Lakeside Retreat, 5.42 Acres, 7 Units

10 Saltbox Rd, Milton, NH 03851
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Mixed-Use Triplex in Downtown Milton
$399,900
2,970 SF

Mixed-Use Triplex in Downtown Milton

Charming mixed-use triplex with commercial space and residential units.

6 Dawson St, Milton, NH 03851
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Rochester, NH Mixed-Use Investment
$495,000
1.40 Acres

Rochester, NH Mixed-Use Investment

High-yield multifamily & commercial property.

287 Milton Rd, Rochester, NH 03868
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Highway-Commercial Property with Large Garage
$450,000
0.56 Acres

Highway-Commercial Property with Large Garage

Versatile commercial property with garage, renovated ranch, and highway access.

8 Phillips Ln, Rochester, NH 03868
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Sanford Land with Urban Zoning
$110,000
2.00 Acres

Sanford Land with Urban Zoning

Two-acre parcel with urban zoning, existing structure.

45 Payne St, Sanford, ME 04083
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Explore Off-Market Properties in Sanford, ME

Consider similar Off-Market properties in Sanford, ME. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

649 Main St

649 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 2,712 SF
Value Estimation by Request
649 Main St, Springvale, ME 04083-1727
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17 Washington St

17 Washington St

OFFICE/RESIDENTIAL (MIXED USE) • 14,248 SF
Value Estimation
$1,750,000
17 Washington St, Sanford, ME 04073-3020
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911 Main St

911 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 5,695 SF
Value Estimation
$795,000
911 Main St, Sanford, ME 04073-3565
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578 Lebanon St

578 Lebanon St

OFFICE/RESIDENTIAL (MIXED USE) • 2,232 SF
Value Estimation by Request
578 Lebanon St, Sanford, ME 04073-5300
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18 Gerrish Dr

18 Gerrish Dr

OFFICE/RESIDENTIAL (MIXED USE) • 844 SF
Value Estimation by Request
18 Gerrish Dr, Sanford, ME 04073-3766
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481 Main St

481 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 23,734 SF
Value Estimation
$2,305,000
481 Main St, Springvale, ME 04083-1400
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1068 Main St, Unit 5B

1068 Main St, Unit 5B

OFFICE/RESIDENTIAL (MIXED USE) • 1,528 SF
Value Estimation by Request
1068 Main St, Sanford, ME 04073-3792
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1413 Main St

1413 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 1,646 SF
Value Estimation by Request
1413 Main St, Sanford, ME 04073-3638
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1538 Main St

1538 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 2,873 SF
Value Estimation by Request
1538 Main St, Sanford, ME 04073-2409
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147 Mt Hope Rd

147 Mt Hope Rd

OFFICE/RESIDENTIAL (MIXED USE) • 1,152 SF
Value Estimation by Request
147 Mt Hope Rd, Sanford, ME 04073-5014
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81 Cottage St

81 Cottage St

OFFICE/RESIDENTIAL (MIXED USE) • 5,652 SF
Value Estimation
$650,000
81 Cottage St, Sanford, ME 04073-1837
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49 Shaws Rdg Rd

49 Shaws Rdg Rd

OFFICE/RESIDENTIAL (MIXED USE) • 2,328 SF
Value Estimation by Request
49 Shaws Rdg Rd, Sanford, ME 04073-6206
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596 Main St

596 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 1,632 SF
Value Estimation by Request
596 Main St, Springvale, ME 04083-1621
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2 Hughes St

2 Hughes St

OFFICE/RESIDENTIAL (MIXED USE) • 2,506 SF
Value Estimation by Request
2 Hughes St, Sanford, ME 04073-2104
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665 Main St

665 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 1,344 SF
Value Estimation by Request
665 Main St, Springvale, ME 04083-1727
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15 Elm St

15 Elm St

OFFICE/RESIDENTIAL (MIXED USE) • 4,178 SF
Value Estimation
$770,000
15 Elm St, Sanford, ME 04073-3915
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56 Tall Pnes Dr

56 Tall Pnes Dr

OFFICE/RESIDENTIAL (MIXED USE) • 2,348 SF
Value Estimation by Request
56 Tall Pnes Dr, Sanford, ME 04073-5940
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440 Main St

440 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 3,900 SF
Value Estimation
$685,000
440 Main St, Springvale, ME 04083-1820
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835 Main St

835 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 3,200 SF
Value Estimation by Request
835 Main St, Sanford, ME 04073-3522
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446 Main St

446 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 4,048 SF
Value Estimation
$575,000
446 Main St, Springvale, ME 04083-1884
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1052 Main St

1052 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 1,281 SF
Value Estimation by Request
1052 Main St, Sanford, ME 04073-3623
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481 Main St

481 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 23,449 SF
Value Estimation
$2,155,000
481 Main St, Springvale, ME 04083-1400
View details
48 Winter St

48 Winter St

OFFICE/RESIDENTIAL (MIXED USE) • 9,579 SF
Value Estimation
$1,230,000
48 Winter St, Sanford, ME 04073-3325
View details

Sanford, ME Mixed-Use Properties Investment Opportunities Market Analysis

Explore 102 mixed-use properties for sale in Sanford, ME on our real estate platform. These investment opportunities span a total of 10,871,339 square feet of properties for sale, with an estimated market value of $21,684,900.

Sale prices for multi use buildings in Sanford, ME start at $210,000, averaging $289,132, and reaching up to $655,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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