For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Space Uses
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
  • Hospitality
  • Sports & Entertainment
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

Sanford, ME Commercial Real Estate for Lease

List
Map
9 results
Sanford Retail Center Space Available
$7 SF/Yr
29,373 SF

Sanford Retail Center Space Available

1364 Main St, Sanford, ME

Retail spaces available in Sanford's busiest shopping center.

  • Located in the Sanford region's busiest retail center.
  • Opportunity to join established retailers such as Shaw's, Dollar Tree, Ollie's, Starbucks, Pizza Hut, and Planet Fitness.
  • Variety of suite sizes available, from 1,500 SF to a large space of 21,367 SF in Suite 19.
  • Competitive lease rates, ranging from $8 to $12 PSF.
  • Multiple suite options available: Suite 7, 11, 17, 18a, 19, and 21.
Updated: Nov 24, 2025
View details
Main Street Retail Space Available
$14 SF/Yr
1,100 SF

Main Street Retail Space Available

1299 Main St, Sanford, ME

Retail space in a mini mall with ample parking.

  • Excellent location on Main Street.
  • Open layout suitable for various businesses.
  • Kitchen in back end.
  • Huge signage opportunity.
  • Plenty of parking in front and back.
Updated: Sep 4, 2025
View details
Renovated Office Space Available
$19 SF/Yr
1,500 SF

Renovated Office Space Available

Renovated office space for lease with flexible configurations.

860 Main St, Sanford, ME
View details
Sanford Warehouse/Distribution Property for Sale
Contact for pricing

Sanford Warehouse/Distribution Property for Sale

9,500 SF warehouse/distribution property for sale in Sanford, Maine.

103 River St, Sanford, ME
View details
Retail Space Available For Rent
Contact for pricing
13,320 SF

Retail Space Available For Rent

Retail spaces available, ranging from 4,900 to 13,320 SqFt.

1247 Main Street, Sanford, ME 4073
View details
Updated Office Suite in Sanford
$8 SF/Yr
11,000 SF

Updated Office Suite in Sanford

Recently updated office suite for sublease in South Sanford.

1 Eagle Dr, Sanford, ME 4073
View details
Highly Visible Pad Opportunity
Contact for pricing

Highly Visible Pad Opportunity

Land for rent with excellent signage opportunity on roundabout.

1410 Main St, Sanford, ME
View details
Route 109 Development Site
Contact for pricing

Route 109 Development Site

Approximately 12-acre development site for ground lease or build-to-suit.

1440 Main St, Sanford, ME
View details
Updated Two-Story Sanford Office Suite
Contact for pricing

Updated Two-Story Sanford Office Suite

Recently updated office suite for sublease in Sanford, Maine.

One Eagle Drive, Sanford, ME 04073
View details
Based on your search, we've compiled 34 Potential Opportunities for your consideration. Besides 9 Active listings in Sanford, ME, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 21 Properties for Sales.

Explore Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Berwick Office Space For Lease
Contact for pricing

Berwick Office Space For Lease

Well-located office space in Berwick, ideal for various business uses.

7A Industry Drive, Berwick, ME 03901
View details
Berwick Commercial Space For Lease
Contact for pricing

Berwick Commercial Space For Lease

1,500 SF bay space ideal for contractors or light industrial.

7b Industry Drive, Berwick, ME 03901
View details
Kennebunk Office Space For Rent
$27 SF/Yr
3,134 SF

Kennebunk Office Space For Rent

Office space with open floor plan and architectural details.

4 Main St, Kennebunk, ME
View details
Professional Office Suites For Rent
$15 SF/Yr
1,602 SF

Professional Office Suites For Rent

Professional office suites in high-traffic location near downtown Kennebunk.

3-7 Webhannet Pl, Kennebunk, ME
View details

Explore Similar Spaces for Sale in Sanford, ME

Consider Similar Space for Sale. We found 21 Spaces matching your search parameters.

Sanford Commercial Property For Sale
$889,900
17,568 SF

Sanford Commercial Property For Sale

Multi-building commercial property in Sanford, Maine, near Main St.

6 Breary Avenue, Sanford, ME 04073
View details
Sanford Commercial Building For Sale
$1,180,000
7,288 SF

Sanford Commercial Building For Sale

7288 SF commercial building with retail and storage space.

1306 Main Street, Sanford, ME 04073
View details
Sanford Commercial Investment Opportunity
$3,600,000
28,118 SF

Sanford Commercial Investment Opportunity

28,000+ sq ft office park near Main Street.

1137 Main Street, Sanford, ME 04073
View details
Sanford, ME Development Opportunity
$125,000
1.10 Acres

Sanford, ME Development Opportunity

1.10 acre lot available for development in Sanford, Maine.

Gatehouse Road lot: 2, Sanford, ME 04073
View details
Sanford, Maine Development Opportunity
$125,000
1.13 Acres

Sanford, Maine Development Opportunity

1.13 acre lot in prime southern Maine location.

Gatehouse Road lot: 3, Sanford, ME 04073
View details
Sanford, ME Development Opportunity
$125,000
1.13 Acres

Sanford, ME Development Opportunity

1.13 acre lot in southern Maine for development.

Gatehouse Road lot: 1, Sanford, ME 04073
View details
Sanford Land Parcel on Route
$350,000
108,900.00 Acres

Sanford Land Parcel on Route

2.5 acre parcel with frontage on busy Route 109.

R15-83 Main Street, Sanford, ME 04073
View details
Versatile Commercial Building with Retail
$1,180,000
7,288 SF

Versatile Commercial Building with Retail

7288 SF commercial building with retail and flexible space.

1306 Main Street, Sanford, ME 4073
View details
Sanford Land For Sale
Contact for pricing
0.23 Acres

Sanford Land For Sale

0.23 acre lot near downtown Sanford, Maine.

Dudley Street, Sanford, ME 04073
View details
Sanford Commercial Property For Sale
$889,900
17,568 SF

Sanford Commercial Property For Sale

Multi-building commercial property with retail, warehouse, and redevelopment potential.

6 Breary Ave, Sanford, ME 4073
View details
Sanford Land with Solar Income
$810,000
923,472 SF

Sanford Land with Solar Income

21.2-acre parcel with solar income and building potential.

Lot 24 Walnut Brook Road, Sanford, ME 4073
View details
Commercial Lot Near Retail Hub
$275,000
95,832.00 Acres

Commercial Lot Near Retail Hub

2.2-acre commercial lot with high traffic count in Sanford.

Lot 1C Main Street / Rte 109, Sanford, ME 04073
View details
Sanford Land Near Airport
$449,000
37.00 Acres

Sanford Land Near Airport

Land with flexible zoning near Sanford Regional Airport.

17 Airport Rd, Sanford, ME
View details
Approved Land Parcel For Sale
$350,000
2.00 Acres

Approved Land Parcel For Sale

2.0 AC parcel approved for fast food with drive-through.

68 Alfred Rd, Sanford, ME
View details
Warehouse, Storage, and Manufacturing Buildings
$4,950,000
32.32 Acres

Warehouse, Storage, and Manufacturing Buildings

Mix of buildings with laydown area and power generation.

563 New Dam Rd, Sanford, ME
View details

Sanford, ME Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Sanford, ME with 9 listings featured on our commercial real estate exchange. The current inventory includes 113,256,000 square feet of properties with an estimated lease value of $33 SF/Yr.

Estimated lease rates for Commercial real estate in Sanford, ME begin at $14 SF/Yr, with an average of $16 SF/Yr and extend to $19 SF/Yr.
List
Map