Add Listing
    Sanford, ME
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    Sanford, ME Commercial Real Estate for Lease

    Notify Me
    List
    Map
    Kennebunk, ME Waterboro, ME Wells, ME
    10 results
    Renovated Office Space Available
    $875/Mo
    1,500 SF
    Renovated Office Space Available

    860 Main St, Sanford, ME

    Renovated office space for lease with flexible configurations.
    • Newly renovated space with elegant gloss flooring and new heating/AC pumps.
    • Flexible configurations possible for office or retail use (600, 800, or 1500 +/- SF).
    • Excellent street visibility and ample signage space.
    • On‑site and street parking available.
    • Includes private offices, bathrooms, and a large open area.
    Updated: Nov 24, 2025
    View details
    Retail Space Available For Rent
    $14 SF/Yr
    4,000 SF
    Retail Space Available For Rent

    1458 Main Street, Sanford, ME 4073

    4,000 SF retail space available in October 2026.
    • High traffic counts offer excellent exposure.
    • Ample parking for customers and staff.
    • Great visibility ensures your business gets noticed.
    • Close proximity to Center for Shopping and Sanford High School.
    • 4,000sf space.
    Updated: May 1
    View details
    Main Street Retail Space Available
    $14 SF/Yr
    1,100 SF
    Main Street Retail Space Available

    Retail space in a mini mall with ample parking.

    1299 Main St, Sanford, ME

    View details
    Retail Space Available For Rent
    Contact for pricing
    13,320 SF
    Retail Space Available For Rent

    Retail spaces available, ranging from 4,900 to 13,320 SqFt.

    1247 Main Street, Sanford, ME 4073

    View details
    Prime Retail Space in Sanford
    Contact for pricing
    Prime Retail Space in Sanford

    Commercial space with high visibility and foot traffic in Sanford.

    15 Washington St, Sanford, ME 4073

    View details
    Updated Office Suite in Sanford
    $8 SF/Yr
    11,000 SF
    Updated Office Suite in Sanford

    Recently updated office suite for sublease in South Sanford.

    1 Eagle Dr, Sanford, ME 4073

    View details
    Highly Visible Pad Opportunity
    Contact for pricing
    Highly Visible Pad Opportunity

    Land for rent with excellent signage opportunity on roundabout.

    1410 Main St, Sanford, ME

    View details
    Route 109 Development Site
    Contact for pricing
    Route 109 Development Site

    Approximately 12-acre development site for ground lease or build-to-suit.

    1440 Main St, Sanford, ME

    View details
    Updated Two-Story Sanford Office Suite
    $8 SF/Yr
    Updated Two-Story Sanford Office Suite

    Recently updated office suite for sublease in Sanford, Maine.

    One Eagle Drive, Sanford, ME 04073

    View details
    Sanford Retail Center Space Available
    $7 SF/Yr
    29,373 SF
    Sanford Retail Center Space Available

    Retail spaces available in Sanford's busiest shopping center.

    1364 Main St, Sanford, ME

    View details
    Based on your search, we've compiled 39 Potential Opportunities for your consideration. Besides 10 Active listings in Sanford, ME, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 25 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Professional Office Suites For Rent
    $15 SF/Yr
    1,602 SF
    Professional Office Suites For Rent

    Professional office suites in high-traffic location near downtown Kennebunk.

    3-7 Webhannet Pl, Kennebunk, ME

    View details
    Modern Office Spaces For Rent
    $850/Mo
    365 SF
    Modern Office Spaces For Rent

    Pristine office spaces ranging from 200 to 5200 sq ft.

    1 Alewive Park Rd, Kennebunk, ME

    View details
    Waterboro Retail/Office Build-to-Suit Opportunity
    $25 SF/Yr
    3,250 SF
    Waterboro Retail/Office Build-to-Suit Opportunity

    Up to 30,000 SF available for retail or office.

    8 Dunkin Run, East, Waterboro, ME

    View details
    Retail/Office Build-to-Suit Opportunity
    $25 SF/Yr
    2,300 SF
    Retail/Office Build-to-Suit Opportunity

    Up to 2,300± SF retail/office space available for rent.

    40 Sokokis Trail, Waterboro, ME 4030

    View details

    Similar Spaces for Sale in Sanford, ME

    Consider Similar Space for Sale. We found 25 Spaces matching your search parameters.

    Sanford Commercial Building For Sale
    $1,180,000
    7,288 SF
    Sanford Commercial Building For Sale

    7288 SF commercial building with retail and storage space.

    1306 Main Street, Sanford, ME 04073

    View details
    Turnkey Multi-Level Restaurant and Bar
    $650,000
    6,921 SF
    Turnkey Multi-Level Restaurant and Bar

    Turnkey restaurant and bar with full kitchen, multi-level seating, and built-in refrigeration for efficient operations.

    16 School Street, Sanford, ME 04073

    View details
    Sanford Commercial Property For Sale
    $889,900
    17,568 SF
    Sanford Commercial Property For Sale

    Multi-building commercial property in Sanford, Maine, near Main St.

    6 Breary Avenue, Sanford, ME 04073

    View details
    Sanford Commercial Investment Opportunity
    $3,600,000
    28,118 SF
    Sanford Commercial Investment Opportunity

    28,000+ sq ft office park near Main Street.

    1137 Main Street, Sanford, ME 04073

    View details
    Unique Sanford Multi-Family with Garage
    $459,900
    2,352 SF
    Unique Sanford Multi-Family with Garage

    Versatile multi-family property with oversized garage and unique features.

    106 High Street, Sanford, ME 04073

    View details
    Sanford Land with Storage Building
    $180,000
    0.12 Acres
    Sanford Land with Storage Building

    Land with storage building, conversion potential, convenient location.

    11 Wilson Street, Sanford, ME 04073

    View details
    Sanford Commercial Building with Utilities
    $180,000
    1,144 SF
    Sanford Commercial Building with Utilities

    1144 SF building with utilities, conversion potential, convenient location.

    11 Wilson Street, Sanford, ME 04073

    View details
    Sanford, ME Development Opportunity
    $125,000
    1.10 Acres
    Sanford, ME Development Opportunity

    1.10 acre lot available for development in Sanford, Maine.

    Gatehouse Road lot: 2, Sanford, ME 04073

    View details
    Sanford, Maine Development Opportunity
    $125,000
    1.13 Acres
    Sanford, Maine Development Opportunity

    1.13 acre lot in prime southern Maine location.

    Gatehouse Road lot: 3, Sanford, ME 04073

    View details
    Sanford, ME Development Opportunity
    $125,000
    1.13 Acres
    Sanford, ME Development Opportunity

    1.13 acre lot in southern Maine for development.

    Gatehouse Road lot: 1, Sanford, ME 04073

    View details
    Sanford Land For Sale
    Contact for pricing
    0.23 Acres
    Sanford Land For Sale

    0.23 acre lot near downtown Sanford, Maine.

    Dudley Street, Sanford, ME 04073

    View details
    Sanford Commercial Property For Sale
    $889,900
    17,568 SF
    Sanford Commercial Property For Sale

    Multi-building commercial property with retail, warehouse, and redevelopment potential.

    6 Breary Ave, Sanford, ME 4073

    View details
    Versatile Commercial Building with Retail
    $1,180,000
    7,288 SF
    Versatile Commercial Building with Retail

    7288 SF commercial building with retail and flexible space.

    1306 Main Street, Sanford, ME 4073

    View details
    Sanford Land with Solar Income
    $810,000
    923,472 SF
    Sanford Land with Solar Income

    21.2-acre parcel with solar income and building potential.

    Lot 24 Walnut Brook Road, Sanford, ME 4073

    View details

    Sanford, ME Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Sanford, ME with 10 listings featured on our commercial real estate exchange. The current inventory includes 46,973 square feet of properties with an estimated lease value of $50 SF/Yr.

    Estimated lease rates for Commercial real estate in Sanford, ME begin at $7 SF/Yr, with an average of $10 SF/Yr and extend to $14 SF/Yr.
    List
    Map

    Browse Commercial real estate for Lease Near Sanford, ME

    Popular Searches in Sanford, ME

    Popular Categories

    Most Searched ZIP Codes in Sanford, ME

    • 04073

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!