For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Space Uses
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
  • Hospitality
  • Sports & Entertainment
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

San Francisco, CA Mixed-use Properties for Lease

List
Map
13 results
Retail Space in Rincon Center
Contact for pricing
2,289 SF

Retail Space in Rincon Center

121 Spear St, San Francisco, CA

Premier retail opportunity in San Francisco's South Financial District.

  • Premier retail opportunities in San Francisco’s South Financial District.
  • Located steps from the Embarcadero and Ferry Building.
  • Dynamic mixed‑use destination spanning an entire city block.
  • Features Class A office, residential, and retail spaces.
  • Benefit from 1,500+ on‑site employees and top tenants including Google and Twilio.
Updated: Nov 10, 2025
View details
Creative Live/Work Loft Space
$68 SF/Yr
1,950 SF

Creative Live/Work Loft Space

1 Clarence Place - Unit 9, San Francisco, CA 94107

1,950 SF creative live/work loft, ideal for small teams.

  • 1,950 SF Live/Work Loft
  • Suitable for small and collaborative teams
  • Located down a clean and private alley
  • Pleasant and safe work environment
  • Many lunch options nearby
Updated: Nov 21, 2025
View details
Mixed-Use Building Available For Rent
Contact for pricing

Mixed-Use Building Available For Rent

Mixed-use building with flexible floor configurations available for rent.

San Francisco, CA 94103
View details
Historic Mixed-Use Complex
Contact for pricing
133,000 SF

Historic Mixed-Use Complex

Modern mixed-use complex with retail, office, and entertainment spaces.

1000 Van Ness Ave, San Francisco, CA 94109
View details
Downtown Flex Space with Views
Contact for pricing
6,600 SF

Downtown Flex Space with Views

6,600 SF flex space with downtown views for lease.

761-765 Bryant St, San Francisco, CA
View details
Union Square Mixed-Use Retail Space
Contact for pricing
3,164 SF

Union Square Mixed-Use Retail Space

Retail space in a mixed-use building in Union Square.

55 Stockton St, San Francisco, CA
View details
Commercial Space For Lease
Contact for pricing

Commercial Space For Lease

Commercial space available for lease.

San Francisco, CA 94111
View details
Commercial Space For Lease
$30 SF/Yr

Commercial Space For Lease

Mixed-use, retail, office, and industrial spaces available for lease.

San Francisco, CA 94103
View details
Mixed-Use Buildings in San Francisco
Contact for pricing

Mixed-Use Buildings in San Francisco

Luxurious mixed-use buildings near public transport and tech companies.

Trinity Place, San Francisco, CA 94104
View details
Mixed-Use Complex in San Francisco
Contact for pricing

Mixed-Use Complex in San Francisco

14-story mixed-use complex near UC Law San Francisco.

198 McAllister St, San Francisco, CA 94102
View details
Creative Live/Work Loft Space
$68 SF/Yr
1,950 SF

Creative Live/Work Loft Space

1,950 SF creative live/work loft, perfect for collaborative teams.

1-2 Clarence Pl, San Francisco, CA
View details
Mixed-Use Property Near Waterfront
Contact for pricing
10,500 SF

Mixed-Use Property Near Waterfront

Mixed-use property with retail, commercial space, and childcare center.

88 Broadway & 735 Davis St, San Francisco, CA 94111
View details
Creative-Flex Space in Vibrant Location
Contact for pricing

Creative-Flex Space in Vibrant Location

Renovated mixed-use property near SoMa, Mission Dolores, and Lower Haight.

San Francisco, CA 94103
View details
Based on your search, we've compiled 123 Potential Opportunities for your consideration. Besides 13 Active listings in San Francisco, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 102 Properties for Sales.

Explore Mixed-use properties for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Mixed-Use Retail Space Available
Contact for pricing
2,552 SF

Mixed-Use Retail Space Available

Retail space in modern mixed-use development, Oakland, CA.

438 West Grand Avenue, Oakland, CA 94612
View details
Mixed-Use Development in Uptown District
Contact for pricing
27,589 SF

Mixed-Use Development in Uptown District

Mixed-use property with retail, office, lofts, and apartments for rent.

2335 Broadway, Oakland, CA 94612
View details
111 Pine Ave
$29 SF/Yr

111 Pine Ave

14,087 - 28,174 SF of Space Available in South San Francisco, CA 94080

111 Pine Ave, South San Francisco, CA 94080, South San Francisco, CA 94080
View details
111 Pine Ave
$29 SF/Yr

111 Pine Ave

14,087 - 28,174 SF of Space Available in South San Francisco, CA 94080

111 Pine Ave, South San Francisco, CA 94080, South San Francisco, CA 94080
View details

Explore Similar Spaces for Sale in San Francisco, CA

Consider Similar Space for Sale. We found 102 Spaces matching your search parameters.

Mixed-Use Property in Mission District
$3,750,000
4,302 SF

Mixed-Use Property in Mission District

Well-maintained mixed-use property with retail and residential units in San Francisco.

3265 22nd Street, San Francisco, CA 94110
View details
San Francisco Mixed-Use Trophy Asset
$18,000,000
3,356 SF

San Francisco Mixed-Use Trophy Asset

Rare mixed-use property with income and residential development potential.

3516-3518 Sacramento Street, San Francisco, CA 94118
View details
Victorian Mixed-Use San Francisco Property
$1,698,000
4,350 SF

Victorian Mixed-Use San Francisco Property

Charming Victorian with commercial space and residential units in San Francisco.

418-422 Haight Street, San Francisco, CA 94117
View details
Mixed-Use Property in San Francisco
$998,000
2,900 SF

Mixed-Use Property in San Francisco

Mixed-use property with income potential in Excelsior District.

4487-4489 Mission Street, San Francisco, CA 94112
View details
Mixed-Use Building, Inner Richmond District
$1,899,000
1,980 SF

Mixed-Use Building, Inner Richmond District

Mixed-use property in Inner Richmond near Golden Gate Park.

558-560 Balboa St, San Francisco, CA 94118
View details
Mixed-Use Property in San Francisco
$1,200,000
3,075 SF

Mixed-Use Property in San Francisco

Mixed-use property with retail space and residential units in San Francisco.

4871 Mission ST, San Francisco, CA 94112
View details
Mixed-Use Property with Income Potential
$995,000
0.06 Acres

Mixed-Use Property with Income Potential

Multi-unit, mixed-use property in San Francisco with income potential.

345-347 Brazil Avenue, San Francisco, CA 94112
View details
Boutique Commercial Condo in Japantown
$565,000
521 SF

Boutique Commercial Condo in Japantown

521 SF commercial condo ideal for owner-user in central location.

1600 Webster Street #C2, San Francisco, CA 94115
View details
Mixed-Use Investment Property, San Francisco
$1,650,000
2,400 SF

Mixed-Use Investment Property, San Francisco

Two-unit mixed-use property in Laurel Heights neighborhood.

2843 Geary, San Francisco, CA 94118
View details
Updated Mixed-Use Building Near Civic
$3,680,000
13,500 SF

Updated Mixed-Use Building Near Civic

Three-level mixed-use building near transportation and amenities.

1118 Howard Street, San Francisco, CA 94103
View details
West Portal Mixed-Use Investment
$6,950,000
5,972 SF

West Portal Mixed-Use Investment

Prime mixed-use property in San Francisco's West Portal neighborhood.

24 West Portal Avenue, San Francisco, CA 94127
View details

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Fontana Commercial Land Lease
$0.01 SF/Yr
1,565 SF

Prime Fontana Commercial Land Lease

4.33-acre commercial land for ground lease in Fontana, CA.

16203 Foothill Boulevard, Fontana, CA 92335
View details
Commercial Land for Lease
$3,500 /Mo

Commercial Land for Lease

9.33 acres of commercial land available for lease.

12660 E Gateway Boulevard, El Paso, TX 79938
View details
10 Acres Development Site McKinney
Contact for pricing

10 Acres Development Site McKinney

10-acre development site in McKinney, TX, for lease.

3843 Co Rd 317, Mckinney, TX 75069
View details
Cleared Commercial Lot For Lease
Contact for pricing

Cleared Commercial Lot For Lease

1.33-acre commercial lot in growing New Braunfels market.

943 King Arthur, New Braunfels, TX 78130
View details

San Francisco, CA Mixed-use properties Leasing Opportunities Market Analysis

Explore Mixed-use properties leasing options in San Francisco, CA with 13 listings featured on our commercial real estate exchange. The current inventory includes 84,942,000 square feet of properties with an estimated lease value of $68 SF/Yr.

Estimated lease rates for Mixed-use properties in San Francisco, CA begin at $68 SF/Yr, with an average of $68 SF/Yr and extend to $68 SF/Yr.
List
Map