Saint Joseph, MO Medical Office Space for Rent & Lease

Updated: Oct 31, 2025

Medical Office with Exam Rooms

1011 E Saint Maartens Drive, St Joseph, MO 64506

$14 SF/Yr

0.63 AC lot

Eight appointment rooms, including four with installed plumbing
Two executive suites with private half bathrooms
Reception area for client and patient arrivals
Shared downstairs breakroom and kitchenette
0.63‑acre office park site with parking lot

View details

Updated: Jun 25

Medical Office Space with Exam Rooms

3725 A Gene Field Road, St Joseph, MO 64506

$1,700/Mo

0.79 AC lot

Medical office space with reception area, private office, 3 exam rooms or additional offices, and breakroom
0.79‑acre parcel in St. Joseph, MO
CP‑3 zoning
Built in 1997
Parking lot on site

View details

Medical Office Space with Parking

1515 St Joseph Avenue, St Joseph, MO 64505

$12 SF/Yr

1.06 AC lot

M-2-zoned facility includes private and public restrooms plus on-site lot parking.

View details

Medical Office Building

20994 State Route K, Saint Joseph, MO 64505

Contact for pricing

10,288 sqft 3.20 AC lot

Commercial building on 3.20 acres with paved parking, two entrances, and a full-service veterinary clinic setup.

View details

Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 4 Active listings in Saint Joseph, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Executive Hills Office/Medical Building

10015 N. AMBASSADOR DR., Kansas City, MO 64154

$14 SF/Yr

39,840 sqft

Office/Medical building in Executive Hills with excellent I-29 access.

View details

Flexible Retail-Office Medical Space

1501 S Us Highway 169, Smithville, MO 64089

Contact for pricing

1,400 sqft

Renovation underway with modernized interiors and updated building systems, plus ample on-site parking.

View details

Retail Space Under Full Renovation

1501 S Us Highway 169, Smithville, MO 64089

Contact for pricing

2,100 sqft

Retail space with flexible use potential and ample on-site parking, with full building renovation underway for early 2026 delivery.

View details

Medical Office Suites for Lease

5400 N Oak Trfy, Kansas City, MO 64118

Contact for pricing

8,393 sqft

Second-generation medical office suites are available and can be divided up to 8,400 RSF.

View details

Similar Spaces for Sale in Saint Joseph, MO

Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

Medical Office Building with Lobby

20994 State Route K N/A, St Joseph, MO 64505

$1,450,000

10,288 sqft 3.20 AC lot

Flexible commercial layout includes multiple offices, support rooms, and a dedicated rear suite for administrative or specialized functions.

View details

Medical Office Building

20994 State Route K, St Joseph, MO 64505

$1,450,000

3.27 AC lot

Configured veterinary clinic with multiple offices, support rooms, a reception area, and paved on-site parking.

View details

Medical Office Building with Expansion Land

3904 Beck Road, St Joseph, MO 64506

$2,100,000

2.51 AC lot

C-3-zoned medical office property with existing healthcare occupancy, available space, and a dedicated parking lot.

View details

Medical Office Owner-User Opportunity

2111 N Woodbine Rd, Saint Joseph, MO

Contact for pricing

9,000 sqft 2.30 AC lot

Medicare approved ambulatory surgery center ideal for medical office.

View details

Medical Center on Large Lot

3111 N Belt Highway, St Joseph, MO 64506

$399,000

0.70 AC lot

Veterinary clinic building with parking and C-3 zoning.

View details

Medical Office Suite with 10 Rooms

3919 Messanie St, St Joseph, MO 64506

$750,000

Previously built for medical use, the suite includes 10 private rooms, wet and dry systems, and dedicated parking.

View details

Saint Joseph, MO Medical Office Space Lease Rates & Market Statistics

Browse 4 Medical Office Space listings for lease in Saint Joseph, MO on Realmo, a commercial real estate marketplace serving the Saint Joseph area. The current inventory totals 10,288 square feet of properties.

Medical Office Space lease rates in Saint Joseph range from $12 SF/Yr at the entry level to $14 SF/Yr at the top of the market, averaging $13 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $13 SF/Yr, the local average runs 7% below Missouri's state average of $13.94 SF/Yr.

Saint Joseph accounts for 100% of the 4 medical office space listings currently available across Buchanan County, where a nearby market includes St Joseph. Medical Office Space is one of the more limited space types in Saint Joseph, with just 4 listings currently available — a scarcity worth factoring into lease negotiations. Also worth a look for tenants weighing alternatives: Office Units (27 listings) and Office buildings (3 listings) elsewhere in the Saint Joseph market.

Saint Joseph, MO Medical Office Space for Lease

1011 E Saint Maartens Drive, St Joseph, MO 64506

3725 A Gene Field Road, St Joseph, MO 64506

1515 St Joseph Avenue, St Joseph, MO 64505

20994 State Route K, Saint Joseph, MO 64505