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    Opelousas, LA
    Medical Premises

    Opelousas, LA Medical Office Space for Sale

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    Port Barre, LA Washington, LA Lawtell, LA Arnaudville, LA Sunset, LA Grand Coteau, LA Church Point, LA Carencro, LA
    8 properties
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    Standalone Office Building
    Updated: Apr 16
    Standalone Office Building

    523 S Main Street, Opelousas, LA 70570

    $110,000
    1,500 sqft 0.09 AC lot
    1,500‑square‑foot standalone office building
    0.09‑acre parcel at 523 S Main Street, Opelousas, LA 70570
    Commercial zoning
    Central heating and central air conditioning
    Carpet and tile flooring with 1 bathroom
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    Updated Medical Office Building
    Updated: Oct 10, 2025
    Updated Medical Office Building

    828 Creswell Lane, Opelousas, LA 70570

    $250,000
    4,516 sqft 0.26 AC lot
    4,516‑square‑foot medical office building on 0.26 acres
    Currently leased to a tenant
    Commercial zoning
    Five bathrooms and tile flooring
    Central air conditioning and electric central heat
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    Updated Medical Office Space
    Updated Medical Office Space

    507 N Market Street, Opelousas, LA 70570

    $187,000
    2,371 sqft

    Commercial medical office with a reception lobby, multiple private rooms, accessible entry, and recently updated interior systems.

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    See hot listings in Opelousas

    Scored against comparables nationwide. These are worth a look.

    Scored against comparables nationwide. These are worth a look.

    Cap Rate available after sign in
    Est. NOI available after sign in
    Local Demand available after sign in
    Medical Office with NNN Lease
    Medical Office with NNN Lease

    828 Creswell Ln, Opelousas, LA 70570

    $250,000
    4,516 sqft

    Medical office property occupied by a medical tenant under a five-year NNN lease with annual escalations.

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    Standalone Office Building
    Standalone Office Building

    523 S Main St, Opelousas, LA 70570

    $110,000
    1,500 sqft

    Vacant professional workspace with potential for medical, legal, or creative office use.

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    Medical Office Building
    Medical Office Building

    507 N Market St, Opelousas, LA 70570

    $187,000
    2,371 sqft

    Brick medical office building with updated interior systems, lobby/reception layout, and rear employee parking.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Medical Office Building
    Medical Office Building

    2218 George Dr, Opelousas, LA 70570

    $299,000
    2,822 sqft

    Existing medical office suitable for professional or healthcare-related reuse.

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    Former Medical Office Building
    Former Medical Office Building

    528 E Vine St, Opelousas, LA 70570

    Contact for pricing
    7,010 sqft

    Former medical office space with convenient access and parking along a busy commuter and retail thoroughfare.

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    Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 8 Active listings in Opelousas, LA, we suggest exploring several alternatives: 4 properties in Nearby Cities

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Renovated Office Building
    Renovated Office Building

    4605 N University Avenue, Carencro, LA 70520

    $490,000
    3,049 sqft 0.66 AC lot

    Two-suite office property with medical space, shared amenities, and covered parking.

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    Renovated Two-Suite Office Building
    Renovated Two-Suite Office Building

    4605 N University Ave, Carencro, LA 70520

    $490,000
    3,049 sqft

    CM-1-zoned office property with medical improvements and shared common space.

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    Seven-Office Professional Building
    Seven-Office Professional Building

    1769 W Main St, Ville Platte, LA 70586

    $98,900
    2,324 sqft

    Configured with private offices, support areas, and a dedicated meeting room.

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    Office Building with Off-Street Parking
    Office Building with Off-Street Parking

    550 E Hickory Street, Ville Platte, LA 70586

    $65,000
    1,400 sqft 1.18 AC lot

    Commercially zoned office property with a flexible interior, two bathrooms, central systems, and on-site off-street parking.

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    Opelousas, LA Medical Office Space Market Trends and Statistics

    Explore 8 medical office space for sale in Opelousas, LA, showcased through 8 active listings on our real estate platform. These investment opportunities span a total of 26,606 square feet of properties for sale, with an estimated market value of $1,393,000.

    Sale prices for medical spaces in Opelousas, LA start at $110,000, averaging $199,000, and reaching up to $299,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office buildings 14
    Medical Office Space 13
    Office Units 9
    Creative space 3

    Demographics Overview

    Population 37K
    Population Growth (5Y) -7.0%
    Median Household Income $45,276
    College Educated 10.2%

    High-Yield Neighborhoods for Investment

    Identify Opelousas submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    70570 $199K

    Taxes & Financing

    Tax Rate (average for all types) 7.87%
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in St. Landry Parish

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in St. Landry Parish

    Residential Income

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