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    Opelousas, LA Commercial Real Estate for Lease

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    Carencro, LA Arnaudville, LA Ville Platte, LA
    12 listings
    Opelousas Commercial Building For Lease
    Contact for pricing
    1,665 SF
    Opelousas Commercial Building For Lease

    1004 Creswell Lane, Opelousas, LA 70570

    Commercial building in high-traffic area, ideal for retail or offices.
    • High traffic location near I‑49.
    • Ideal for retail space or professional offices.
    • Open floor space with two private offices.
    • Parking in front and rear.
    • Common break/coffee area with restroom.
    Updated: Mar 11
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    Opelousas Warehouse For Rent
    Contact for pricing
    2,940 SF
    Opelousas Warehouse For Rent

    8599 Highway 182, Opelousas, LA 70570

    Secure commercial warehouse space available for rent in Opelousas.
    • Secure commercial property featuring a 2,940 sq. ft. warehouse.
    • Landlord covers taxes and insurance, simplifying your expenses.
    • Benefit from a newly lined roof and updated electrical system.
    • Spacious 9'6'' x 9'2'' door provides easy access for deliveries and operations.
    • Situated on approximately 0.27 acres next to Dollar General.
    Updated: Sep 25, 2025
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    Industrial Building on Two Acres
    Contact for pricing
    4,800 SF
    Industrial Building on Two Acres

    4800SF industrial building with I-49 frontage on 2 acres.

    3383 I 49 S Service Road, Opelousas, LA 70570

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    Opelousas Office Space For Rent
    Contact for pricing
    4,326 SF
    Opelousas Office Space For Rent

    Large office space in high-traffic, highly visible location.

    816 Creswell Lane, Opelousas, LA 70570

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    Medical/Professional Office Building For Lease
    $9,000/Mo
    Medical/Professional Office Building For Lease

    Two-story building ideal for medical or professional office use.

    4049 I 49 S Service Rd, Opelousas, LA 70570

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    Move-In Ready Office Suite
    $1,650/Mo
    2,100 SF
    Move-In Ready Office Suite

    Move-in ready office space suited for professional services, including therapy and wellness uses.

    414 S Main St, Opelousas, LA 70570

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    Opelousas Office Space For Lease
    Contact for pricing
    2,100 SF
    Opelousas Office Space For Lease

    Move-in ready office space in the heart of Opelousas.

    414 S Main Street, Opelousas, LA 70570

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    Medical Office and Surgical Center
    Contact for pricing
    6,424 SF
    Medical Office and Surgical Center

    Modern medical office and surgical center with move-in-ready interiors, exam and procedure rooms, and ample on-site parking.

    1418 Heather Dr, Opelousas, LA 70570

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    Retail Space in Opelousas
    Contact for pricing
    7,200 SF
    Retail Space in Opelousas

    7,200 SF retail space available for rent.

    2418 South Union St, Opelousas, LA

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    Medical Office Suite Off I-49
    $3,000/Mo
    3,014 SF
    Medical Office Suite Off I-49

    Office suite available right off I-49 in Opelousas, offering a convenient location for medical users.

    5620 I 49 S Service Rd, Opelousas, LA 70570

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    Opelousas Office in Opportunity Zone
    $197,000 SF/Yr
    2,100 SF
    Opelousas Office in Opportunity Zone

    Large office space with modern amenities in Opelousas, Louisiana.

    223 S Main Street, Opelousas, LA 70570

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    Opelousas Commercial Corner Lot
    $5,900/Mo
    Opelousas Commercial Corner Lot

    Corner lot in fast food corridor, ideal for restaurant.

    1130 S Union Street, Opelousas, LA 70570

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    Based on your search, we've compiled 83 Potential Opportunities for your consideration. Besides 12 Active listings in Opelousas, LA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 67 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Office/Warehouse Flex Space
    $1,700/Mo
    3,000 SF
    Office/Warehouse Flex Space

    Versatile office and insulated warehouse configuration with roll-up loading for industrial or service users.

    205 Four Park Rd, Lafayette, LA 70507

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    Turn Key Restaurant For Lease
    $29 SF/Yr
    Turn Key Restaurant For Lease

    Restaurant For Lease

    3730 NE Evangeline Thruway, Unit F, Carencro, LA 70520

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    Commercial Land in Carencro, LA
    $599,000 SF/Yr
    4,000 SF
    Commercial Land in Carencro, LA

    Located off I-49, high-traffic frontage road.

    4300 NE Evangeline Thruway, Carencro, LA 70520

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    Equipped Industrial Property Near Roadways
    Contact for pricing
    16,068 SF
    Equipped Industrial Property Near Roadways

    Equipped industrial property with office and warehouse space for lease.

    338 Thoroughbred Drive, Lafayette, LA 70507

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    Similar Spaces for Sale in Opelousas, LA

    Consider Similar Space for Sale. We found 67 Spaces matching your search parameters.

    Versatile Commercial Space, Opelousas, LA
    $750,000
    19,125 SF
    Versatile Commercial Space, Opelousas, LA

    Former skating rink with open space, ideal for various ventures.

    1427 W Linwood Drive, Opelousas, LA 70570

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    Opelousas Commercial Building For Sale
    $269,000
    2,949 SF
    Opelousas Commercial Building For Sale

    Versatile commercial building on busy Main St in Opelousas, LA.

    822 S Main Street, Opelousas, LA 70570

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    Turnkey Auto Body Shop Opportunity
    $349,500
    3,813 SF
    Turnkey Auto Body Shop Opportunity

    Ready-to-go auto body facility with major components already installed.

    331 E Jefferson Street, Opelousas, LA 70570

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    Opelousas Commercial Property For Sale
    $375,000
    5,343 SF
    Opelousas Commercial Property For Sale

    5,343 SF commercial building on 1.06 acres in Opelousas.

    2614 S Union Street, Opelousas, LA 70570

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    Mixed-Use Office and Warehouse
    $399,000
    8,823 SF
    Mixed-Use Office and Warehouse

    A commercial building with two front office suites and a climate-controlled rear warehouse, supported by on-site parking.

    1604 Kerr Street, Opelousas, LA 70570

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    Opelousas Commercial Building For Sale
    $175,000
    3,420 SF
    Opelousas Commercial Building For Sale

    Turnkey 3,420 sq. ft. commercial building in Opelousas, LA.

    232 E Leonard Avenue, Opelousas, LA 70570

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    Iconic Jim Bowie Building Opportunity
    $150,000
    580 SF
    Iconic Jim Bowie Building Opportunity

    Spacious commercial property in the heart of Downtown Opelousas.

    129 W Landry Street, Opelousas, LA 70570

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    Opelousas Commercial Building For Sale
    $110,000
    1,500 SF
    Opelousas Commercial Building For Sale

    1,500 sq ft commercial building in Opelousas's NMU District.

    523 S Main Street, Opelousas, LA 70570

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    Industrial Workshop with Quonset Building
    $150,000
    1,228 SF
    Industrial Workshop with Quonset Building

    Quonset workshop plus multiple additions and outbuildings, supported by a 3-bedroom home and separate driveway access.

    2010 Cummings Street, Opelousas, LA 70570

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    Opelousas Commercial Property For Sale
    $230,000
    3,106 SF
    Opelousas Commercial Property For Sale

    Commercial property on 2.8 acres with expansion potential.

    720 Mccarthy Lane, Opelousas, LA 70570

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    Opelousas Medical Office Building
    $250,000
    4,516 SF
    Opelousas Medical Office Building

    Updated medical office building with tenant in place, great investment.

    828 Creswell Lane, Opelousas, LA 70570

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    Opelousas Commercial Property For Sale
    $139,900
    9,800 SF
    Opelousas Commercial Property For Sale

    Commercial property with frontage on Hwy 190 West.

    606 W Landry Street, Opelousas, LA 70570

    View details

    Opelousas, LA Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Opelousas, LA with 12 listings featured on our commercial real estate exchange. The current inventory includes 7,214 square feet of properties with an estimated lease value of $197,021.

    Estimated lease rates for Commercial real estate in Opelousas, LA begin at $9 SF/Yr, with an average of $65,673 and extend to $197,000.
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