South Dakota Medical offices for Rent & Lease

$1.00 SF/Yr

5,600 SF

Class A Office Space Available

1220 Mt. Rushmore Rd, Rapid City, SD 57701

Move-in ready office space ideal for medical or professional services.

Prime location on Mt Rushmore Road with unparalleled visibility and access.
Move‑in ready Class A office space.
Well‑suited for medical practices or professional service providers, offering a functional and adaptable layout.
Includes 6 private offices, a conference room with kitchenette, and a 700 SF classroom.
Features built‑in workstations and a clerical room.

Updated: Mar 13, 2025

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$14 SF/Yr

28,000 SF

Aspen Centre West Offices

660 Flormann St, Rapid City, SD 57701

Versatile office suites, prime location.

Affordable office space for lease in Aspen Centre West, starting at $400/month, utilities included.
Up to 14,000 square feet of customizable office space available, with smaller individual offices also an option.
Convenient location off Mt. Rushmore Rd., in a high‑traffic area.
Building amenities include elevator access, shared break room, conference room, and recently updated common areas.
14,000 square feet of space immediately available.

Updated: Dec 11, 2024

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$22 SF/Yr

21,040 SF

Prime Sioux Falls Retail Space

Class A Retail/Office, High Traffic Location

6205 Old Village Pl, Sioux Falls, SD 57108

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$10 SF/Yr

32,400 SF

Midland Shopping Center Office Suites

Rapid City, SD Office Space for Lease

909 Saint Patrick St, Rapid City, SD 57701

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$18 SF/Yr

15,814 SF

Rowe 57: Prime Sioux Falls Office Space

Modern Office Suites in Thriving Community

5025 Bahnson Ave, Sioux Falls, SD 57103

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$25 SF/Yr

27,651 SF

Steel District Office Space

Modern Sioux Falls Office Suites, 1,890-6,650 SF

150 4 Pl, Sioux Falls, SD 57104

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$14 SF/Yr

9,160 SF

River Drive Office Spaces Available

High-visibility Union County office suites

1244-1248 River Dr, North Sioux City, SD 57049

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$8 SF/Yr

85,194 SF

Downtown Sioux Falls Office Space

Prime Office Space, Flexible Layouts, Downtown Sioux Falls

101 Phillips Ave, Sioux Falls, SD 57104

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$8 SF/Yr

36,500 SF

IMA Building: Sioux Falls Office Space

Medical & Traditional Office Suites Available

6709 Minnesota Ave, Sioux Falls, SD 57108

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$10 SF/Yr

1,754 SF

Prime Sioux Falls Office Space

2,880 sq ft, Central Location, 55 Parking Spaces

3905 Western Ave, Sioux Falls, SD 57105

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$25 SF/Yr

7,003 SF

Bakker Landing: Prime Tea Office Space

Modern Office Suites in Growing Tea, SD

0 Venture St, Tea, SD 57064

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$15 SF/Yr

3,768 SF

Meadows Square Office Suites

Prime Sioux Falls Office Space Available

3801 34Th St, Sioux Falls, SD 57106

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$13 SF/Yr

1,900 SF

West 41st Street Retail Space

Prime Sioux Falls retail/office opportunity.

5107 41St St, Sioux Falls, SD 57106

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$12 SF/Yr

13,237 SF

Willow Creek Office Suites Available

Prime Sioux Falls office space, flexible layouts.

1704 Cleveland Ave, Sioux Falls, SD 57103

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$146 SF/Yr

1,570 SF

Rapid City Office Suites for Lease

Downtown Rapid City Office Space - 1570 sq ft

701 Main St, Rapid City, SD 57701

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$24 SF/Yr

8,594 SF

Dakota Dental Building Office Space

8,594 sq ft Office in Sioux Falls, SD

7600 Brookside Cir, Sioux Falls, SD 57108

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$16 SF/Yr

26,120 SF

Oakbrook II Office Space for Lease

Versatile Sioux Falls Office Building

5032 Bur Oak Pl, Sioux Falls, SD 57108

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$24 SF/Yr

2,338 SF

West 57th St. Premier Space

High-traffic retail/office opportunity

4209 57Th St, Sioux Falls, SD 57108

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$24 SF/Yr

8,673 SF

The Point on Main Street

Downtown Spearfish Office Space

344 Main St, Spearfish, SD 57783

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Rock Island Building: Prime Office Space

$15 SF/Yr

13,413 SF

Rock Island Building: Prime Office Space

Downtown Sioux Falls office building, multiple suites available.

300 Phillips Ave, Sioux Falls, SD 57104

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$21 SF/Yr

660 SF

Rapid City Executive Office Suite

Downtown Rapid City office, 660 sq ft.

522 7Th St, Rapid City, SD 57701

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$10 SF/Yr

20,278 SF

Harrisburg Crossing Office Space

Flexible Office Suites in Prime Location

220 Cliff Ave, Sioux Falls, SD 57103

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$12 SF/Yr

9,936 SF

Prime Office Condo/Lease Opportunity

Versatile Office Space, High-Traffic Location

4214 38Th St, Sioux Falls, SD 57106

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$25 SF/Yr

5,000 SF

Prairie Towers: Class A Office Space

Modern Sioux Falls Offices, Multiple Sizes Available

200 85Th St, Sioux Falls, SD 57108

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South Dakota Medical offices Leasing Opportunities Market Analysis

Explore Medical offices leasing options in South Dakota with 43 listings featured on our commercial real estate exchange. The current inventory includes 17,457,105,600 square feet of properties with an estimated lease value of $584 /Mo.

Estimated lease rates for Medical offices in South Dakota begin at $1.00 SF/Yr, with an average of $20 SF/Yr and extend to $146 SF/Yr.

South Dakota Medical Offices for Lease

Class A Office Space Available

Move-in ready office space ideal for medical or professional services.

Aspen Centre West Offices

Versatile office suites, prime location.

Prime Sioux Falls Retail Space

Midland Shopping Center Office Suites

Rowe 57: Prime Sioux Falls Office Space

Steel District Office Space

River Drive Office Spaces Available

Downtown Sioux Falls Office Space

IMA Building: Sioux Falls Office Space

Prime Sioux Falls Office Space

Bakker Landing: Prime Tea Office Space

Meadows Square Office Suites

West 41st Street Retail Space

Willow Creek Office Suites Available

Rapid City Office Suites for Lease

Dakota Dental Building Office Space

Oakbrook II Office Space for Lease

West 57th St. Premier Space

The Point on Main Street

Rock Island Building: Prime Office Space

Rapid City Executive Office Suite

Harrisburg Crossing Office Space

Prime Office Condo/Lease Opportunity

Prairie Towers: Class A Office Space

South Dakota Medical offices Leasing Opportunities Market Analysis

Medical offices by market

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South Dakota Medical Offices for Lease

Class A Office Space Available

Move-in ready office space ideal for medical or professional services.

Aspen Centre West Offices

Versatile office suites, prime location.

Prime Sioux Falls Retail Space

Midland Shopping Center Office Suites

Rowe 57: Prime Sioux Falls Office Space

Steel District Office Space

River Drive Office Spaces Available

Downtown Sioux Falls Office Space

IMA Building: Sioux Falls Office Space

Prime Sioux Falls Office Space

Bakker Landing: Prime Tea Office Space

Meadows Square Office Suites

West 41st Street Retail Space

Willow Creek Office Suites Available

Rapid City Office Suites for Lease

Dakota Dental Building Office Space

Oakbrook II Office Space for Lease

West 57th St. Premier Space

The Point on Main Street

Rock Island Building: Prime Office Space

Rapid City Executive Office Suite

Harrisburg Crossing Office Space

Prime Office Condo/Lease Opportunity

Prairie Towers: Class A Office Space

South Dakota Medical offices Leasing Opportunities Market Analysis

Medical offices by market

Popular cities

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