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    Monroe County, PA Medical Office Space for Lease

    14 results
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    Versatile Commercial Space in Shawnee
    $12 SF/Yr
    4,610 SF

    Versatile Commercial Space in Shawnee

    106 Shawnee Sq Dr, East Stroudsburg, PA 18301

    Adaptable 4,610 SF space in high-traffic Shawnee Square.

    • Prime commercial location in Shawnee Square, Shawnee‑on‑Delaware, PA, offering high visibility.
    • Easily accessible location just off Interstate 80 (Exits 309 and 310).
    • Flexible space of 4,610 sq ft, divisible into two units.
    • Shares a plaza with the local Post Office, ensuring consistent daily traffic.
    • First‑floor layout is fully ADA compliant.
    Updated: Feb 16
    View details
    Tannersville Commercial Lease Opportunity
    $3,450 / Mo
    2,590 SF

    Tannersville Commercial Lease Opportunity

    106 Talon Dr, Tannersville, PA 18372

    Prime commercial space suitable for medical, dental, legal, or veterinary practices.

    • Prime location just off Route 611 offering high visibility and accessibility.
    • Well‑suited for professional services with 9 office/patient rooms and dedicated lab space.
    • Enhanced security features: security window with controlled access, silent alarm connected to local police, and multiple security cameras.
    • Reliable power supply with a back‑up generator.
    • Ample parking with two private lots.
    Updated: Dec 12, 2025
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    East Stroudsburg Office Space Available
    $675 / Mo
    450 SF

    East Stroudsburg Office Space Available

    Professional/Medical office space for rent in East Stroudsburg, PA.

    507 Seven Bridge Rd, East Stroudsburg, PA 18301
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    East Stroudsburg Professional Office Suite
    $3,250 / Mo
    2,165 SF

    East Stroudsburg Professional Office Suite

    Professional and medical office suite for rent in East Stroudsburg.

    507 Seven Bridge Rd, East Stroudsburg, PA 18301
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    Functional Office Space Available
    $1,600 / Mo
    12,000 SF

    Functional Office Space Available

    Well-located office space in Bartonsville, PA, available April 1, 2026.

    3355 Route 611, Bartonsville, PA 18321
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    Commercial Space Ready For Occupancy
    $5,900 / Mo

    Commercial Space Ready For Occupancy

    4,300 sqft commercial space suitable for various uses.

    208 Front Kevin Ln, Brodheadsville, PA 18322
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    East Stroudsburg Office Space Available
    $2,615 / Mo
    27,573 SF

    East Stroudsburg Office Space Available

    Office spaces for lease near Lehigh Valley Hospital - Pocono.

    239 E Brown St Unit, East Stroudsburg, PA 18301
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    East Stroudsburg Office Space Available
    $4,168 / Mo
    27,573 SF

    East Stroudsburg Office Space Available

    Office spaces for lease near Lehigh Valley Hospital - Pocono.

    239 E Brown St Unit, East Stroudsburg, PA 18301
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    East Stroudsburg Office/Medical Space
    $1,275 / Mo
    651 SF

    East Stroudsburg Office/Medical Space

    Professional office building near I-80 on Route 209.

    507 7 Bridges Rd, East Stroudsburg, PA 18301
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    East Stroudsburg Office Space Available
    $3,413 / Mo
    27,573 SF

    East Stroudsburg Office Space Available

    Office spaces for lease near Lehigh Valley Hospital - Pocono.

    239 E Brown St Unit, East Stroudsburg, PA 18301
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    Stroudsburg Commercial Space For Rent
    $2,250 / Mo
    2,100 SF

    Stroudsburg Commercial Space For Rent

    2,100 SF commercial space suitable for office, medical, or retail.

    828 Monroe St, Stroudsburg, PA 18360
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    Professional Office Suite For Rent
    $2,950 / Mo
    54,000 SF

    Professional Office Suite For Rent

    Professional/Medical office suite available in Tobyhanna, PA.

    100 Community Dr, Tobyhanna, PA 18466
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    Stroudsburg Medical Office Space
    $18 SF/Yr
    6,000 SF

    Stroudsburg Medical Office Space

    Class A medical office space for lease in Stroudsburg.

    1845 W Main St, Stroudsburg, PA 18360
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    Seven Bridge Road Office Suites
    $18 SF/Yr
    12,375 SF

    Seven Bridge Road Office Suites

    Class A Office Space, East Stroudsburg, PA

    529 Seven Bridge Rd, East Stroudsburg, PA 18301
    View details
    Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 14 Active listings in Monroe County, PA, we suggest exploring alternatives. Similar 9 Properties for Sales.

    Explore Similar Spaces for Sale in Monroe County, PA

    Consider Similar Space for Sale. We found 9 Spaces in Nearby Locations matching your search parameters.

    Brodheadsville Commercial Building on 2.61 Acres
    Pending
    $489,000
    3,864 SF

    Brodheadsville Commercial Building on 2.61 Acres

    3,864 SF commercial building on 2.61 acres for sale.

    1830 Route 209, Brodheadsville, PA 18322
    View details
    East Stroudsburg Commercial Building For Sale
    Pending
    $600,000
    3,360 SF

    East Stroudsburg Commercial Building For Sale

    Freestanding 3,360 sq ft brick building on 0.59 acres.

    209 Skyline Dr, East Stroudsburg, PA 18301
    View details
    Professional/Medical Office Building For Sale
    $2,950,000
    18,444 SF

    Professional/Medical Office Building For Sale

    18,400 sq ft professional/medical office building in Tobyhanna, PA.

    300 Community Dr, Tobyhanna, PA 18466
    View details
    Stroudsburg Commercial Investment Opportunity
    $1,600,000
    4,328 SF

    Stroudsburg Commercial Investment Opportunity

    Commercial investment property with diversified income stream and in-place tenancy.

    1674 N 9Th St, Stroudsburg, PA 18360
    View details
    East Stroudsburg Medical/Office Building
    $599,000
    5,484 SF

    East Stroudsburg Medical/Office Building

    5,484 sq ft commercial building in Poconos medical district.

    371 E Brown St, East Stroudsburg, PA 18301
    View details
    Former Inn on 3.6 Acres
    $995,000
    12,813 SF

    Former Inn on 3.6 Acres

    Former Inn with cottages on 3.6 acres for sale.

    2735 Route 390, Canadensis, PA 18325
    View details
    East Stroudsburg Medical Office Building
    $1,899,000
    13,541 SF

    East Stroudsburg Medical Office Building

    13,600 SF medical office building in growing healthcare hub.

    500 Vna Rd, East Stroudsburg, PA 18301
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    East Stroudsburg Medical Office Building
    $325,000
    1,888 SF

    East Stroudsburg Medical Office Building

    1,888 SF Medical Office, 100% Occupied

    383 Brown St, East Stroudsburg, PA 18301
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    Prime Medical Office Condo in Tobyhanna, PA
    $1,568,467
    6,067 SF

    Prime Medical Office Condo in Tobyhanna, PA

    High-Yield Medical Office Investment

    100 Community Dr, Tobyhanna, PA 18466
    View details

    Monroe County, PA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Monroe County, PA with 23 listings featured on our commercial real estate exchange. The current inventory includes 7,825,989,600 square feet of properties with an estimated lease value of $143 SF/Yr.

    Estimated lease rates for Medical Office Space in Monroe County, PA begin at $0.66 SF/Yr, with an average of $11 SF/Yr and extend to $23 SF/Yr.
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