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    Syracuse, NY Medical Office Space for Lease

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    Medical Office Space Available
    $19 SF/Yr
    5,126 SF

    Medical Office Space Available

    792 North Main Street, North Syracuse, NY 13212

    5,126 SF medical office suite for lease.

    • 5,126 RSF medical office suite featuring 9 exam rooms, 3 bathrooms, 1 nurses’ station, and 3 administrative offices.
    • Highly visible location in Village Medical Park, less than one mile from the I‑481/I‑81 interchange.
    • Ample parking (6.37:1000).
    • Proximity to Syracuse Hancock International Airport (± 3.1 miles) and downtown Syracuse/major hospitals (±8 miles).
    • Located near numerous retailers and restaurants including Wegmans, Lowes, The Home Depot, and Price Chopper.
    Updated: Mar 25
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    Medical Building with Flexible Suites
    Contact for pricing
    5,000 SF

    Medical Building with Flexible Suites

    2112 Erie Blvd E, Syracuse, NY

    Professional medical building with suites available for lease.

    • High‑visibility location directly off Erie Blvd with 17,000+ daily vehicle traffic.
    • Versatile suites suitable for medical or professional office use.
    • Ample on‑site parking.
    • Three suites available, ranging from 1,900 SF to 5,000 SF.
    • Flexible layouts designed for various practices (neurology, urgent care, general medical, etc.).
    Updated: Jul 28, 2025
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    Downtown Syracuse Office Space Available
    $15 SF/Yr
    11,936 SF

    Downtown Syracuse Office Space Available

    Medical or general office space for lease in Syracuse.

    600 E Genesee St, Syracuse, NY
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    Class A Office Building Syracuse
    Contact for pricing
    14,000 SF

    Class A Office Building Syracuse

    Professionally managed multi-tenant office building with medical and traditional spaces.

    1304 Buckley Rd, Syracuse, NY 13212
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    Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 4 Active listings in Syracuse, NY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 4 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Suites For Lease
    Contact for pricing
    15,384 SF

    Medical Office Suites For Lease

    Medical office suites available in Fayetteville, NY.

    4000 Medical Center Drive, Fayetteville, NY 13066
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    Fayetteville Office Space For Rent
    Contact for pricing
    40,000 SF

    Fayetteville Office Space For Rent

    Office space ideal for medical or professional use near I-690.

    6800 E Genesee St, Fayetteville, NY
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    New Development Opportunity in Syracuse
    Contact for pricing
    26,000 SF

    New Development Opportunity in Syracuse

    New Class A medical/office or office/warehouse facility for lease.

    6731 Fly Rd, East Syracuse, NY
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    Medical Office Near Route 481
    $25 SF/Yr

    Medical Office Near Route 481

    Medical office space with convenient access and ample parking.

    4939 Brittonfield Pkwy, East Syracuse, NY 13057
    View details

    Explore Similar Spaces for Sale in Syracuse, NY

    Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

    Mixed-Use Building with Dental Practice
    $185,000
    2,600 SF

    Mixed-Use Building with Dental Practice

    2600 SF building with dental practice and apartment.

    1500 Grant Blvd and Mayar St, Syracuse, NY
    View details
    Freestanding Commercial Building on Erie
    $450,000
    4,200 SF

    Freestanding Commercial Building on Erie

    4,200 SF commercial building on Erie Blvd available for sale.

    1810 Erie Blvd E, Syracuse, NY 13210
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    Well-Maintained Two-Story Office Building
    $1,695,000
    22,867 SF

    Well-Maintained Two-Story Office Building

    Two-story office building with basement and excellent onsite parking.

    5232 Witz Dr, N Syracuse, NY
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    Multi-Tenant Office Building For Sale
    $899,000
    15,200 SF

    Multi-Tenant Office Building For Sale

    Stand-alone office building with ample parking and convenient access.

    716 James St, Syracuse, NY 13203
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Land in Upper St Clair
    $50,000

    Prime Land in Upper St Clair

    Commercial land for lease in Upper St Clair, PA.

    2585 Maple Lane, Upper St Clair, PA 15241
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    Highway 72 Corner Lot
    $6,500 /Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

    30472 Highway 72, Madison, AL 35756
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    Prime Commercial Lot For Rent
    $7,500 /Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    0 Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details

    Syracuse, NY Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Syracuse, NY with 4 listings featured on our commercial real estate exchange. The current inventory includes 502,072,560 square feet of properties with an estimated lease value of $31 SF/Yr.

    Estimated lease rates for Medical Office Space in Syracuse, NY begin at $12 SF/Yr, with an average of $15 SF/Yr and extend to $19 SF/Yr.
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    Browse Medical Office Space for Lease Near Syracuse, NY

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