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St Joseph, MO Medical Office Space for Lease

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St. Joseph Avenue Commercial Space
$12 SF/Yr
46,174 SF

St. Joseph Avenue Commercial Space

1515 St Joseph Ave, St Joseph, MO 64505

8500 SF commercial space suitable for various businesses.

  • Large 8500 SF office space, suitable for various uses.
  • Potential for division into 3 separate spaces.
  • Favorable lease rates: $10/SF for entire space or $12/SF for divided spaces, plus expenses.
  • Drive‑thru possibility on the south side of the building.
  • Ideal for food service tenant.
Updated: Aug 25, 2025
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Office/Medical Space on Frederick Avenue
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Office/Medical Space on Frederick Avenue

3109 Frederick Ave, St Joseph, MO 64506

1500 SF office/medical space with ground level access.

  • Ground level/ADA access for all clients and employees.
  • Build‑to‑suit opportunity: Landlord will customize the space.
  • Dedicated parking: Includes 3‑5 spaces with access to a larger lot.
  • Flexible layout with a reception area, waiting area, and 4‑5 private offices/rooms.
  • Suitable for office/medical use.
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Based on your search, we've compiled 9 Potential Opportunities for your consideration. Besides 2 Active listings in St Joseph, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

Explore Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Executive Hills Office/Medical Building
$14 SF/Yr

Executive Hills Office/Medical Building

Office/Medical building in Executive Hills with excellent I-29 access.

10015 N Ambassador Dr, Kansas City, MO 64154
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Barry Road Medical Office Space
Contact for pricing
38,750 SF

Barry Road Medical Office Space

Prime KCMO medical/retail space available.

232 Barry Rd, Kansas City, MO 64155
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Prime Retail Space in Mission
Contact for pricing
4,351 SF

Prime Retail Space in Mission

Retail space in the heart of Mission, Kansas.

7000 Johnson Dr, Mission, KS 66202
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Mission West: Medical Office Space
$12 SF/Yr
20,023 SF

Mission West: Medical Office Space

Prime Medical Office Space Available in Mission, KS

6500 Martway St, Mission, KS 66202
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Explore Similar Spaces for Sale in St Joseph, MO

Consider Similar Space for Sale. We found 3 Spaces in Nearby Locations matching your search parameters.

Medical Office Building For Sale
$2,750,000
2.51 Acres

Medical Office Building For Sale

Medical office building on 2.51 acres with expansion potential.

3904 Beck Rd, St Joseph, MO 64506
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Veterinary Clinic on Belt Highway
$399,000
0.70 Acres

Veterinary Clinic on Belt Highway

2496 SF veterinary clinic on a large 0.7-acre lot.

3111 N Belt Hwy, St Joseph, MO 64506
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St Joseph Commercial Land For Sale
$375,000
1.29 Acres

St Joseph Commercial Land For Sale

1.288 acre commercial lot suitable for retail or office.

3800 Beck Rd, St Joseph, MO 64506
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St Joseph, MO Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in St Joseph, MO with 5 listings featured on our commercial real estate exchange. The current inventory includes 2,011,322,084 square feet of properties with an estimated lease value of $12 SF/Yr.

Estimated lease rates for Medical Office Space in St Joseph, MO begin at $12 SF/Yr, with an average of $12 SF/Yr and extend to $12 SF/Yr.
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