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    Saint Peters, MO Medical Office Space for Lease

    14 results
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    Keaton Crossing Office/Medical Space
    Contact for pricing
    408 SF

    Keaton Crossing Office/Medical Space

    4122-4142 Keaton Crossing Blvd, O Fallon, MO 63368

    Premier office/medical space in O’Fallon's high-demand corridor.

    • Premier office/medical space in desirable Keaton Crossing development
    • Convenient location near Highway K and I‑64/40, providing easy regional access
    • Ideal for medical, dental, or professional office users
    • Modern construction with flexible suite configurations
    • Ample parking and easy access for patients and clients
    Updated: Nov 6, 2025
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    Keaton Crossing Office/Medical Space
    Contact for pricing
    1,400 SF

    Keaton Crossing Office/Medical Space

    4132 Keaton Crossing Blvd, O Fallon, MO 63368

    Premier office/medical space in O'Fallon's high-demand corridor.

    • Premier office/medical space in Keaton Crossing with convenient access to Highway K and I‑64/40.
    • Ideal for medical, dental, or professional office users.
    • Strong demographics and growing population in O’Fallon’s high‑demand corridor.
    • Ample parking and easy access for patients and clients.
    • Modern construction with flexible suite configurations.
    Updated: Nov 6, 2025
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    Keaton Crossing Office/Medical Space
    Contact for pricing
    2,492 SF

    Keaton Crossing Office/Medical Space

    Premier office/medical space in O'Fallon's high-demand corridor.

    4142 Keaton Crossing Blvd, O Fallon, MO 63368
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    Medical/Professional Office Suite For Rent
    Contact for pricing
    7,180 SF

    Medical/Professional Office Suite For Rent

    Medical/professional office suite available for lease with monument signage.

    114 Piper Hill Dr, St Peters, MO 63376
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    Medical Office Space Available
    Contact for pricing
    2,184 SF

    Medical Office Space Available

    Medical office space for lease with abundant parking.

    1630 Marketcenter Blvd, O Fallon, MO
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    Class A Office Building
    Contact for pricing
    5,679 SF

    Class A Office Building

    Class A office building with high visibility and ample parking.

    5301 Veterans Memorial Pkwy, St Peters, MO 63376
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    Winghaven Medical Office Plaza
    $31 SF/Yr
    60,824 SF

    Winghaven Medical Office Plaza

    Class A Medical Office Space Available

    5551 Winghaven Blvd, O'Fallon, MO 63368
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    St. Peters Medical Office Space
    Contact for pricing
    13,000 SF

    St. Peters Medical Office Space

    Prime Medical Office, St. Charles County

    5770 Mexico Rd, St. Peters, MO 63376
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    St. Peters Medical Office Space
    $23 SF/Yr
    9,945 SF

    St. Peters Medical Office Space

    High-quality medical office, ample parking, great location.

    112 Piper Hill Dr, St. Peters, MO 63376
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    Waterbury Plaza: O'Fallon Office Space
    $17 SF/Yr
    45,879 SF

    Waterbury Plaza: O'Fallon Office Space

    Prime O'Fallon, MO office space available.

    929 Waterbury Falls Dr, O'Fallon, MO 63368
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    O'Fallon, MO Medical Office Space
    $22 SF/Yr
    26,000 SF

    O'Fallon, MO Medical Office Space

    Class A Office Suites, Ample Parking

    856 Waterbury Falls Dr, O'Fallon, MO 63368
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    St. Peters Medical Office Space
    $10 SF/Yr
    15,000 SF

    St. Peters Medical Office Space

    1,980 SF Medical Office for Lease

    104 Hospital Dr, St. Peters, MO 63376
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    Updated Surgery Center For Rent
    $26 SF/Yr
    5,676 SF

    Updated Surgery Center For Rent

    Updated surgery center with operating and procedure rooms available for rent.

    5401 Veterans Memorial Pkwy, St Peters, MO 63376
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    Medical/Professional Office Space For Rent
    Contact for pricing
    3,265 SF

    Medical/Professional Office Space For Rent

    Medical and professional office space with prominent signage and ample parking.

    5650 Mexico Rd, St Peters, MO 63376
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    Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 14 Active listings in Saint Peters, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 8 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Missouri Research Park Medical Office
    $22 SF/Yr
    64,167 SF

    Missouri Research Park Medical Office

    St. Peters, MO medical office space for lease.

    20 Missouri Research Park, Saint Charles, MO 63304
    View details
    St Charles Medical/Dental Office
    $20 SF/Yr
    69,260 SF

    St Charles Medical/Dental Office

    2880 SF medical/dental office space in high-traffic area.

    2043 S Old Highway 94, Saint Charles, MO 63303
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    Medical Office Space Available
    Contact for pricing
    6,445 SF

    Medical Office Space Available

    6,445 SF medical office space in Chesterfield, Missouri.

    17300 N Outer 40 Rd, Chesterfield, MO 63005
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    Chesterfield Medical Building Suites Available
    Contact for pricing
    387 SF

    Chesterfield Medical Building Suites Available

    Medical suites available in renovated Chesterfield building with excellent visibility.

    500 Chesterfield Ctr, Chesterfield, MO 63017
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    Explore Similar Spaces for Sale in Saint Peters, MO

    Consider Similar Space for Sale. We found 8 Spaces in Nearby Locations matching your search parameters.

    St. Peters Standalone Office Building
    $560,000
    3,000 SF

    St. Peters Standalone Office Building

    Move-in-ready office building suitable for medical or professional use.

    410 Jungermann Rd, St Peters, MO 63376
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    Remodeled Commercial Property on Jungermann
    $200,000
    0.16 Acres

    Remodeled Commercial Property on Jungermann

    Newly remodeled commercial property on heavily traveled Jungermann Road.

    406 Jungermann Rd, St Peters, MO 63376
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    Leased Office Condo For Sale
    $155,000
    1,800 SF

    Leased Office Condo For Sale

    Leased office condo for sale with a strong cap rate.

    4131-4139 Mexico Rd, Saint Peters, MO 63376
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    O'Fallon Medical Office Space
    Contact for pricing
    6,480 SF

    O'Fallon Medical Office Space

    2,700 SF medical office space in O'Fallon, Missouri.

    1002 Peruque Crossing Ct, O Fallon, MO 63366
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    St. Peters Medical Office Building
    $3,350,000
    26,578 SF

    St. Peters Medical Office Building

    26,578 SF Medical Office, Value-Add Opportunity

    112 Piper Hill Dr, St. Peters, MO 63376
    View details
    St. Charles County Commercial Land
    $1,060,468

    St. Charles County Commercial Land

    Prime commercial land suitable for various developments in Lake St. Louis.

    5.41 Acres Veterans Memorial Pkwy, Lake St Louis, MO 63367
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    Medical Office Building For Sale
    Contact for pricing
    26,578 SF

    Medical Office Building For Sale

    Two-story medical office building in St. Peters, Missouri.

    112 Piper Hill Dr, St Peters, MO 63376
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    Medical Office Building Near Hospital
    Contact for pricing
    1,724 SF

    Medical Office Building Near Hospital

    12,512 SF medical office building near Barnes-Jewish St. Peters Hospital.

    4601 Executive Centre Pkwy, St Peters, MO 63376
    View details

    Saint Peters, MO Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Saint Peters, MO with 22 listings featured on our commercial real estate exchange. The current inventory includes 7,258,141,440 square feet of properties with an estimated lease value of $152 SF/Yr.

    Estimated lease rates for Medical Office Space in Saint Peters, MO begin at $10 SF/Yr, with an average of $21 SF/Yr and extend to $31 SF/Yr.
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    Browse Medical Office Space for Lease Near Saint Peters, MO

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    Most Searched ZIP Codes in Saint Peters, MO

    • 63376
    • 63368
    • 63366
    • 63304
    • 63303

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