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Saint Peters, MO Office Spaces for Lease

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32 properties
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Office Units with Covered Walkway
Updated: Jul 13
Office Units with Covered Walkway

1405 Jungermann Road, St Peters, MO 63376

$2,838/Mo
1,798 sqft 1.23 AC lot
Two connected office suites within a five‑unit retail boutique
Separate bathroom and utility room provided for each suite
Finished interiors include carpet, tile, drywall, and neutral paint
Approximately 60 open parking spaces with covered walkway
Marquee signage rights included
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Medical Office Space with Wash Area
Updated: Sep 20
Medical Office Space with Wash Area

6180 Mexico Road, St Peters, MO 63376

$3,500/Mo
0.76 AC lot
0.76‑acre medical office property at 6180 Mexico Road, St Peters, MO 63376
Layout includes waiting room, reception, 5 rooms, 2 offices, wash area, and holding area
Room dimensions range from 7x10 to 21x7
Lower level provides additional usable space
Separate rear building contains an onsite K9 training facility
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Lower-Level Retail Space
Lower-Level Retail Space

4053 N Saint Peters Parkway, St Peters, MO 63304

$960/Mo
1.84 AC lot

Flexible commercial suite with two open areas, a break room, office area, and ample surface parking.

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All-Brick Professional Office Building
All-Brick Professional Office Building

O Fallon, MO 63368

$18 SF/Yr
5,892 sqft 0.16 AC lot

All-brick office building with 2,946 SF available for lease near Hwy K and US 64 in Keaton Corporate Park.

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Office Unit with Monument Signage
Office Unit with Monument Signage

1234 Jungermann Road, St Peters, MO 63376

$14 SF/Yr
0.55 AC lot

Lower-level office space with multiple private rooms, a conference area, kitchenette, storage, and dedicated restroom.

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Furnished Private Coworking Office
Furnished Private Coworking Office

8-22 Richmond Center Ct, Saint Peters, MO 63376

$1,200/Mo per office
260 sqft

Renovated workspace includes utilities, Wi-Fi, parking, and access to shared business amenities.

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Furnished Coworking Space
Furnished Coworking Space

1000 Mid Rivers Mall Drive Conference, St Peters, MO 63376

$129 SF/Yr
8,800 sqft

Furnished offices provide meeting, mailing, and shared workplace services.

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Office Unit with Workstations
Office Unit with Workstations

4053 N Saint Peters Parkway 4053c-2, St Peters, MO 63304

$800/Mo

C-3-zoned office space with convenient access to Hwy 94 and I-364.

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Office Unit with Conference Room
Office Unit with Conference Room

St Peters, MO 63376

$168 SF/Yr

The suite pairs private work areas with reception space, a kitchenette, storage, and a private restroom.

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Modern Office Space for Lease
Modern Office Space for Lease

11400 Veterans Memorial Pkwy, Lake St Louis, MO 63367

Contact for pricing
1,000 sqft

Flexible office suites with spacious floor plans, customizable layouts, and ample parking for convenient day-to-day operations.

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Renovated Medical Office Suites
Renovated Medical Office Suites

St Peters, MO 63376

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2,724 sqft

Newly renovated second-floor suites ranging from small to large medical or professional office configurations.

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Office Units with Covered Walkway
Office Units with Covered Walkway

C-1405 Jungermann Rd, Saint Peters, MO 63376

$2,838/Mo
1,798 sqft

Three finished office suites in a suburban business park with separate support areas and convenient regional highway access.

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Two-Story Medical Office Building
Two-Story Medical Office Building

St Peters, MO 63376

Contact for pricing
18,763 sqft

Divisible office space includes signage, elevator access, and renovated suite and common-area interiors.

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Medical Office Suite with Monument Signage
Medical Office Suite with Monument Signage

O Fallon, MO 63368

Contact for pricing
2,184 sqft

Medical office suite in a newer building with monument signage and building signage near local amenities.

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Fully Built-Out Medical Office Suite
Fully Built-Out Medical Office Suite

O Fallon, MO 63366

Contact for pricing
1,707 sqft

Fully built-out 1,707 SF medical suite available in a multi-tenant retail building with monument and building signage.

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Office Units
Office Units

O Fallon, MO 63368

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10,600 sqft

Commercial office space suitable for professional users in a substantial multi-suite property.

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Class A Office Building Suite
Class A Office Building Suite

O Fallon, MO 63368

Contact for pricing
1,825 sqft 4.63 AC lot

Class A office building offering upscale finishes within a well-maintained professional setting in O’Fallon’s business corridor.

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Medical/Professional Office Suite For Rent
Medical/Professional Office Suite For Rent

114 Piper Hill Dr, St Peters, MO

Contact for pricing
7,180 sqft 1.00 AC lot

Medical/professional office suite available for lease with monument signage.

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Class A Office Building
Class A Office Building

O Fallon, MO 63368

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Corporate office setting with on-site fitness, café, parking, and prominent signage opportunities.

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St Peters Office Space Available
St Peters Office Space Available

4600 Executive Center Pkwy, St Peters, MO

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4,826 sqft 2.17 AC lot

Office space available in St Peters, move-in November 2025.

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O'Fallon Office Space Available
O'Fallon Office Space Available

O Fallon, MO

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966 sqft 1.33 AC lot

Office space available for lease in O'Fallon, Missouri.

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Furnished Coworking Offices
Furnished Coworking Offices

B-1000 Mid Rivers Mall Dr, Saint Peters, MO 63376

$300/Mo per office

Private workspaces offer shared business amenities, controlled entry, and convenient parking at a corner location.

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Office Space in St. Peters
Office Space in St. Peters

St Peters, MO

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870 sqft 2.31 AC lot

Office space available for lease in St. Peters, Missouri.

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O'Fallon Office Space Available
O'Fallon Office Space Available

O Fallon, MO

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2,000 sqft 0.23 AC lot

2000 square feet of office space for rent.

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Saint Peters, MO Office Spaces Lease Rates & Market Statistics

Explore 32 Office Spaces for lease in Saint Peters, MO on Realmo, a commercial real estate exchange covering the Saint Peters area. The current inventory totals 114,714 square feet of properties — an average of ~3,600 SF per listing.

Asking lease rates for Office Spaces in Saint Peters start at $14 SF/Yr, average $69.59 SF/Yr, and reach $168 SF/Yr at the top of the market. That's a 12x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $69.59 SF/Yr, the local average runs 175% above Missouri's state average of $25.29 SF/Yr.

Saint Peters accounts for 42% of the 77 office spaces currently available across St. Charles County, where nearby markets include Saint Charles and St Peters. By space type, the market includes 24 office units, 8 medical office space listings and 5 office buildings — office buildings typically offer the lowest entry point, while office units command the highest rates.

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