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    Des Moines, IA Medical Office Space for Lease

    9 results
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    Grand Avenue Office and Clinic
    $22 SF/Yr
    152,854 SF

    Grand Avenue Office and Clinic

    3200 Grand Ave, Des Moines, IA 50312

    First-class office and clinic space with parking ramp.

    • Iconic presence along Grand Avenue and the Des Moines skyline.
    • Includes a 116,121 square foot, 10‑story high‑rise building.
    • Features a 14,433 square foot modern conference center.
    • Has a 4‑level parking ramp.
    • Des Moines University Clinic (DMU Clinic) maintains an ongoing presence.
    View details
    Medical Suite in Des Moines
    $18 SF/Yr
    2,247 SF

    Medical Suite in Des Moines

    1215-1415 Pleasant St, Des Moines, IA 50309

    Medical suite for lease within Methodist Medical Center Campus.

    • Located on the Methodist Medical Center Campus
    • Onsite parking provided by an adjacent parking ramp
    • Ideal location for healthcare professionals
    • 2,247 USF available in Suite 102
    • Suite 102 is on the first floor
    Updated: Oct 22, 2025
    View details
    Des Moines Medical Office Space
    $22 SF/Yr
    7,572 SF

    Des Moines Medical Office Space

    Medical office space in Des Moines' major medical corridor.

    330 Laurel St, Des Moines, IA 50314
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    Renovated Office Building in Sherman Hills
    Contact for pricing
    604 SF

    Renovated Office Building in Sherman Hills

    Historically renovated office building suitable for office or medical use.

    800 19Th St, Des Moines, IA 50314
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    Fleur Drive Retail/Medical Space
    Contact for pricing
    2,275 SF

    Fleur Drive Retail/Medical Space

    Well-maintained retail or medical space in a high-traffic area.

    4214 Fleur Dr, Des Moines, IA 50321
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    Des Moines Office Space for Lease
    $12 SF/Yr
    7,260 SF

    Des Moines Office Space for Lease

    Executive/Medical Office, 7,260 SF Total

    4919 Douglas Ave, Des Moines, IA 50310
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    Des Moines Medical Office Space
    $12 SF/Yr
    18,190 SF

    Des Moines Medical Office Space

    Prime Des Moines location, 6,401 SF vacant.

    1300 Walnut St, Des Moines, IA 50319
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    Downtown Des Moines Surgery Center
    Contact for pricing
    57,792 SF

    Downtown Des Moines Surgery Center

    Class A Medical Office Space Available

    450 Laurel St, Des Moines, IA 50314
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    Medical Surgery Center For Lease
    Contact for pricing
    24,000 SF

    Medical Surgery Center For Lease

    Class A medical surgery center adjacent to Mercy One Medical Center.

    450 Laurel St, Des Moines, IA 50314
    View details
    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 9 Active listings in Des Moines, IA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 4 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Space Available
    Contact for pricing
    1,413 SF

    Medical Office Space Available

    Ready-to-use medical suite with ample parking and prime location.

    1031 Office Park Rd, West Des Moines, IA 50265
    View details
    Medical Office Suites, Office Park Rd
    $15 SF/Yr
    8,833 SF

    Medical Office Suites, Office Park Rd

    Multiple suites, 1,413-8,933 sq ft.

    1031 Office Park Rd, West Des Moines, IA 50265
    View details
    Green Meadows West Office Park
    $7 SF/Yr
    14,501 SF

    Green Meadows West Office Park

    Johnston, IA Office Space Available

    5619 86Th St, Johnston, IA 50131
    View details
    Johnston Office Building For Lease
    $6 SF/Yr
    41,080 SF

    Johnston Office Building For Lease

    Prime Johnston location, 41,080 SF available.

    8850 62Nd Ave, Johnston, IA 50131
    View details

    Explore Similar Spaces for Sale in Des Moines, IA

    Consider Similar Space for Sale. We found 4 Spaces in Nearby Locations matching your search parameters.

    Medical Office Near Mercy Campus
    $460,000

    Medical Office Near Mercy Campus

    Medical office space for sale near Mercy Medical Campus.

    303 University Ave, Des Moines, IA 50314
    View details
    Former Dentist Office with Space
    Contact for pricing

    Former Dentist Office with Space

    First and second floor office spaces available for lease.

    4919 Douglas Ave, Des Moines, IA 50310
    View details

    Des Moines, IA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Des Moines, IA with 13 listings featured on our commercial real estate exchange. The current inventory includes 1,207,701,000 square feet of properties with an estimated lease value of $39 SF/Yr.

    Estimated lease rates for Medical Office Space in Des Moines, IA begin at $12 SF/Yr, with an average of $13 SF/Yr and extend to $15 SF/Yr.
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    Browse Medical Office Space for Lease Near Des Moines, IA

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    Most Searched ZIP Codes in Des Moines, IA

    • 50314
    • 50309
    • 50310
    • 50319
    • 50321
    • 50322
    • 50320

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