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Port St Lucie, FL Medical Offices for Lease

11 results
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Medical Office Space For Rent
$24 SF/Yr
998 SF

Medical Office Space For Rent

1801 SE Hillmoor Dr, Port St Lucie, FL 34952

Updated medical office space available for rent in Port St. Lucie.

  • Updated with new vinyl plank flooring, paint, and cabinetry.
  • Features 3 exam rooms and 1 lab/kitchen.
  • Includes 2 bathrooms and 2 business offices.
  • Equipped with central heating and air conditioning.
  • Built in 1996 with block and concrete construction.
Updated: Aug 31, 2025
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Port St. Lucie Executive Office
$1,527 / Mo
998 SF

Port St. Lucie Executive Office

2100 SE Hillmoor Dr, Port St Lucie, FL 34952

Executive office suite in Port St. Lucie medical corridor.

  • Located in the Port St. Lucie medical corridor
  • Ideal for medical, wellness, or professional use
  • Executive office suite featuring 2 private offices and reception/work area
  • Window views of the residential park
  • Elevator access
Updated: Oct 1, 2025
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St. Lucie West Office Space
$23 SF/Yr
2,021 SF

St. Lucie West Office Space

Professional and medical office space in St. Lucie West.

1660 SW St Lucie Blvd W, Port St Lucie, FL
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St. Lucie West Professional Office
$23 SF/Yr
4,964 SF

St. Lucie West Professional Office

Professional office space in a convenient St. Lucie West location.

537 NW Lk Whitney Pl, Port St Lucie, FL
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New Medical Building End Cap
$32 SF/Yr
12,784 SF

New Medical Building End Cap

End cap space in a newly constructed medical building.

1070 Southwest Gatlin Blvd, Port St Lucie, FL 34953
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Medical Office Space on Lake
$19 SF/Yr
1,958 SF

Medical Office Space on Lake

Single-story medical office with lake views and recent upgrades.

573 NW Lk Whitney Pl, Port St Lucie, FL
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St. Lucie West Office Building
$35 SF/Yr
18,000 SF

St. Lucie West Office Building

Office building in a high-growth area with excellent visibility.

9265 Commerce Ctr Dr, Port St Lucie, FL 34986
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Medical Office Space on US-1
$18 SF/Yr
5,473 SF

Medical Office Space on US-1

Newly renovated medical space with high visibility and convenient access.

7664 South Hwy U.S, Port St Lucie, FL 34952
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Former Chiropractic/Wellness Space Available
$23 SF/Yr
2,979 SF

Former Chiropractic/Wellness Space Available

Former chiropractic/wellness space with treatment rooms and private offices.

7041-7043 S Us Highway 1, Port St Lucie, FL 34952
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St Lucie West Office Space
$23 SF/Yr
2,319 SF

St Lucie West Office Space

Medical and professional offices in a convenient location.

291 NW Peacock Blvd, Port St Lucie, FL
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St. Lucie West Office Building
$35 SF/Yr
18,000 SF

St. Lucie West Office Building

Office building in a fast-growing area with excellent visibility.

9265 SW Commerce Ctr Dr, Port St Lucie, FL
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Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 11 Active listings in Port St Lucie, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

Explore Medical offices for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Prime Port St. Lucie Office Space
$13 SF/Yr
56,927 SF

Prime Port St. Lucie Office Space

56,927 SF Office Building, Abundant Parking

900-904 Prima Vista Blvd, Port St. Lucie, FL 34952
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Shared Medical Office Space
$3,500 / Mo
1,604 SF

Shared Medical Office Space

Shared medical office space available near hospital and major roadways.

10377 S Us Hwy, Port Saint Lucie, FL
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Port St. Lucie Office Space
$18 SF/Yr
3,753 SF

Port St. Lucie Office Space

Versatile office space in a high-traffic Port St. Lucie location.

7664 S Us Hwy, Port Saint Lucie, FL
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Cashmere Corners Medical Office
Contact for pricing
85,708 SF

Cashmere Corners Medical Office

Port St. Lucie Medical Office Building

870 St. Lucie Blvd, Port St. Lucie, FL 34986
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Explore Similar Spaces for Sale in Port St Lucie, FL

Consider Similar Space for Sale. We found 5 Spaces in Nearby Locations matching your search parameters.

Medical Office in Excellent Condition
$499,000
0.02 Acres

Medical Office in Excellent Condition

Well-located medical office with five exam rooms and ample space.

439 NW Prima Vista Blvd, Port St Lucie, FL 34983
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St. Lucie West Landmark Building
Contact for pricing
41,753 SF

St. Lucie West Landmark Building

Professional and medical office space in a prominent four-story building.

1660 Saint Lucie West Blvd, Port St Lucie, FL 34986
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Professional/Medical Office Space For Sale
$300,000

Professional/Medical Office Space For Sale

Office space for sale near HCA Florida St. Lucie Hospital.

1400 NE Goldtree Dr, Port St Lucie, FL 34952
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Executive Office Suite For Sale
Contact for pricing

Executive Office Suite For Sale

Class A office suite in Port St. Lucie medical corridor.

2100 SE Hillmoor Dr, Port St Lucie, FL 34952
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Medical Office Building For Sale
$4,700,000

Medical Office Building For Sale

Medical office building with flexible space and modern amenities.

451 SW Bethany Dr, Port St Lucie, FL 34986
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Port St Lucie, FL Medical offices Leasing Opportunities Market Analysis

Explore Medical offices leasing options in Port St Lucie, FL with 16 listings featured on our commercial real estate exchange. The current inventory includes 3,070,677,170 square feet of properties with an estimated lease value of $274 SF/Yr.

Estimated lease rates for Medical offices in Port St Lucie, FL begin at $18 SF/Yr, with an average of $24 SF/Yr and extend to $35 SF/Yr.
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