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    Port St Lucie, FL Medical Office Space for Lease

    11 results
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    Medical Office Space For Rent
    $24 SF/Yr
    998 SF

    Medical Office Space For Rent

    1801 SE Hillmoor Dr, Port St Lucie, FL 34952

    Updated medical office space available for rent in Port St. Lucie.

    • Updated with new vinyl plank flooring, paint, and cabinetry.
    • Features 3 exam rooms and 1 lab/kitchen.
    • Includes 2 bathrooms and 2 business offices.
    • Equipped with central heating and air conditioning.
    • Built in 1996 with block and concrete construction.
    Updated: Aug 31, 2025
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    Port St. Lucie Executive Office
    $1,527 / Mo
    998 SF

    Port St. Lucie Executive Office

    2100 SE Hillmoor Dr, Port St Lucie, FL 34952

    Executive office suite in Port St. Lucie medical corridor.

    • Located in the Port St. Lucie medical corridor
    • Ideal for medical, wellness, or professional use
    • Executive office suite featuring 2 private offices and reception/work area
    • Window views of the residential park
    • Elevator access
    Updated: Oct 1, 2025
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    St. Lucie West Office Space
    $23 SF/Yr
    2,021 SF

    St. Lucie West Office Space

    Professional and medical office space in St. Lucie West.

    1660 SW St Lucie Blvd W, Port St Lucie, FL
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    Medical Office Space on US-1
    $18 SF/Yr
    5,473 SF

    Medical Office Space on US-1

    Newly renovated medical space with high visibility and convenient access.

    7664 South Hwy U.S, Port St Lucie, FL 34952
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    St. Lucie West Office Building
    $35 SF/Yr
    18,000 SF

    St. Lucie West Office Building

    Office building in a fast-growing area with excellent visibility.

    9265 SW Commerce Ctr Dr, Port St Lucie, FL
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    St. Lucie West Office Building
    $35 SF/Yr
    18,000 SF

    St. Lucie West Office Building

    Office building in a high-growth area with excellent visibility.

    9265 Commerce Ctr Dr, Port St Lucie, FL 34986
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    New Medical Building End Cap
    $32 SF/Yr
    12,784 SF

    New Medical Building End Cap

    End cap space in a newly constructed medical building.

    1070 Southwest Gatlin Blvd, Port St Lucie, FL 34953
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    Former Chiropractic/Wellness Space Available
    Contact for pricing
    2,979 SF

    Former Chiropractic/Wellness Space Available

    Former chiropractic/wellness space with treatment rooms and private offices.

    7041-7043 S Us Highway 1, Port St Lucie, FL 34952
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    St. Lucie West Professional Office
    Contact for pricing
    4,964 SF

    St. Lucie West Professional Office

    Professional office space in a convenient St. Lucie West location.

    537 NW Lk Whitney Pl, Port St Lucie, FL
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    Medical Office Space on Lake
    Contact for pricing
    1,958 SF

    Medical Office Space on Lake

    Single-story medical office with lake views and recent upgrades.

    573 NW Lk Whitney Pl, Port St Lucie, FL
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    St Lucie West Office Space
    Contact for pricing
    2,319 SF

    St Lucie West Office Space

    Medical and professional offices in a convenient location.

    291 NW Peacock Blvd, Port St Lucie, FL
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    Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 11 Active listings in Port St Lucie, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 4 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Prime Port St. Lucie Office Space
    $13 SF/Yr
    56,927 SF

    Prime Port St. Lucie Office Space

    56,927 SF Office Building, Abundant Parking

    900-904 Prima Vista Blvd, Port St. Lucie, FL 34952
    View details
    Shared Medical Office Space
    Contact for pricing
    1,604 SF

    Shared Medical Office Space

    Shared medical office space available near hospital and major roadways.

    10377 S Us Hwy, Port Saint Lucie, FL
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    Port St. Lucie Office Space
    Contact for pricing
    3,753 SF

    Port St. Lucie Office Space

    Versatile office space in a high-traffic Port St. Lucie location.

    7664 S Us Hwy, Port Saint Lucie, FL
    View details
    Cashmere Corners Medical Office
    Contact for pricing
    85,708 SF

    Cashmere Corners Medical Office

    Port St. Lucie Medical Office Building

    870 St. Lucie Blvd, Port St. Lucie, FL 34986
    View details

    Explore Similar Spaces for Sale in Port St Lucie, FL

    Consider Similar Space for Sale. We found 4 Spaces in Nearby Locations matching your search parameters.

    Medical Office in Excellent Condition
    $499,000
    0.02 Acres

    Medical Office in Excellent Condition

    Well-located medical office with five exam rooms and ample space.

    439 NW Prima Vista Blvd, Port St Lucie, FL 34983
    View details
    St. Lucie West Landmark Building
    Contact for pricing
    41,753 SF

    St. Lucie West Landmark Building

    Professional and medical office space in a prominent four-story building.

    1660 Saint Lucie West Blvd, Port St Lucie, FL 34986
    View details
    Executive Office Suite For Sale
    Contact for pricing

    Executive Office Suite For Sale

    Class A office suite in Port St. Lucie medical corridor.

    2100 SE Hillmoor Dr, Port St Lucie, FL 34952
    View details
    Medical Office Building For Sale
    $4,700,000

    Medical Office Building For Sale

    Medical office building with flexible space and modern amenities.

    451 SW Bethany Dr, Port St Lucie, FL 34986
    View details

    Port St Lucie, FL Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Port St Lucie, FL with 15 listings featured on our commercial real estate exchange. The current inventory includes 2,538,373,970 square feet of properties with an estimated lease value of $185 SF/Yr.

    Estimated lease rates for Medical Office Space in Port St Lucie, FL begin at $18 SF/Yr, with an average of $26 SF/Yr and extend to $35 SF/Yr.
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    Browse Medical Office Space for Lease Near Port St Lucie, FL

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    Most Searched ZIP Codes in Port St Lucie, FL

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    • 34953
    • 34986

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