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    Naples, FL Medical Office Space for Lease

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    Bonita Springs, FL Estero, FL Fort Myers Beach, FL
    16 results
    Retail Opportunity in Naples, FL
    $35 SF/Yr
    2,400 SF

    Retail Opportunity in Naples, FL

    15495 Tamiami Trl N, Naples, FL

    Retail space available in North Naples & Bonita Springs market.

    • Excellent frontage on US‑41 with over 600 feet.
    • High traffic count: 35,600 ADT on US‑41.
    • Serves the North Naples & Bonita Springs market.
    • Convenient location within Naples' "furniture row".
    • Junior anchor space available.
    Updated: Nov 24, 2025
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    Moorings Professional Building Office Space
    $25 SF/Yr
    1,130 SF

    Moorings Professional Building Office Space

    2335 Tamiami Trl N, Naples, FL

    Office space for lease in a prestigious Naples building.

    • High‑visibility location on US 41 (Tamiami Trail North) in the prestigious Moorings Professional Building.
    • Move‑in ready units with stunning views and abundant natural light.
    • Ideal layout for medical practices or professional services, featuring three private rooms, a reception area, and two bathrooms.
    • Convenient access to NCH and downtown Naples.
    • Generous parking, including one reserved covered space.
    Updated: Feb 18, 2025
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    Downtown Naples Office Suites Available
    $24 SF/Yr

    Downtown Naples Office Suites Available

    Office and medical suites for lease in downtown Naples.

    2400 Tamiami Trl N |, Naples, FL 34103
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    North Naples Medical/Professional Office Space
    Contact for pricing

    North Naples Medical/Professional Office Space

    Premier medical and professional office leasing opportunity in North Naples.

    877 111th Ave N, Naples, FL 34108
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    Medical Office Space Near NCH
    Contact for pricing
    800 SF

    Medical Office Space Near NCH

    800 SF medical office space in a great location.

    840 111th Ave N, Naples, FL 34108
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    Medical Office Space Available
    $24 SF/Yr
    2,877 SF

    Medical Office Space Available

    Professional office space in desirable Naples location for rent.

    708 Goodlette Frank Rd N, Naples, FL
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    Naples Office Space For Rent
    Contact for pricing
    1,592 SF

    Naples Office Space For Rent

    Office space ideal for medical or professional use in Naples.

    3785 Airport Pulling Rd N, Naples, FL
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    Naples Office Space For Rent
    Contact for pricing
    2,475 SF

    Naples Office Space For Rent

    2,475 square foot office space ideal for medical or professional use.

    3765 Airport Pulling Rd N, Naples, FL
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    Medical Office Space For Rent
    Contact for pricing
    3,100 SF

    Medical Office Space For Rent

    Neighborhood medical park office space ready for immediate build-out.

    6400 Davis Blvd, Naples, FL
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    Medical Office Space in Naples
    $24 SF/Yr

    Medical Office Space in Naples

    Medical office building in the heart of Naples, Florida.

    8360 Sierra Meadows Blvd, Naples, FL 34113
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    Downtown Naples Medical Office Space
    $24 SF/Yr

    Downtown Naples Medical Office Space

    Improved medical office space in Downtown Naples, Florida.

    671 Goodlette-Frank Rd, Naples, FL 34102
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    North Naples Medical/Office Suites
    $30 SF/Yr

    North Naples Medical/Office Suites

    Medical/office suites in a well-located North Naples professional complex.

    840 111th Ave N, Naples, FL 34108
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    Medical Office Space Near Hospital
    $25 SF/Yr

    Medical Office Space Near Hospital

    Medical office suites available for rent near NCH North Naples Hospital.

    1890 SW Health Pkwy, Naples, FL 34109
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    Medical/Retail Space For Rent
    $37 SF/Yr

    Medical/Retail Space For Rent

    Ground floor space with high visibility, suitable for medical/retail.

    11121 Health Park Blvd, Naples, FL 34110
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    Medical Office Space Available
    $20 SF/Yr
    90,000 SF

    Medical Office Space Available

    Two-building medical center in desirable Naples sub-market.

    704 Goodlette Rd N, Naples, FL 34102
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    Professional Office and Medical Building
    $25 SF/Yr

    Professional Office and Medical Building

    Three-story office and medical building in South Naples area.

    12250 Tamiami Trail East, Naples, FL 34113
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    Based on your search, we've compiled 33 Potential Opportunities for your consideration. Besides 16 Active listings in Naples, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Bonita Springs Medical/Office Space
    $3,472/Mo

    Bonita Springs Medical/Office Space

    1323 SF grey shell space on Bonita Beach Road.

    11380 Bonita Beach Road SE, Bonita Springs, FL 34135
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    Bonita Springs Retail/Office Space
    $26 SF/Yr
    1,323 SF

    Bonita Springs Retail/Office Space

    Retail or professional office space with prominent signage available for lease.

    11380 Bonita Beach Rd SE, Bonita Springs, FL
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    Medical Building Space For Lease
    $29 SF/Yr
    2,755 SF

    Medical Building Space For Lease

    Medical office space for lease in Estero, delivery Summer 2024.

    9441 Corkscrew Palms Cir, Estero, FL
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    Two-Story Medical Building For Rent
    $22 SF/Yr
    42,200 SF

    Two-Story Medical Building For Rent

    42,200 SF medical building on 4.15 acres in Estero.

    10201 Arcos Ave, Estero, FL 33928
    View details

    Similar Spaces for Sale in Naples, FL

    Consider Similar Space for Sale. We found 9 Spaces matching your search parameters.

    Executive Office Suite in Naples
    $2,200,000
    3,000 SF
    Executive Office Suite in Naples

    Sophisticated office suite with 10 private offices near Downtown.

    599 Tamiami Trl N 101, Naples, FL 34102

    View details
    Prime Land in Naples, FL
    $1,500,000
    2.14 Acres
    Prime Land in Naples, FL

    2.14 acres of commercial land in a sought-after Naples area.

    4721 7th Ave NW lot: 2, Naples, FL 34119

    View details
    Versatile Office Condo in Naples
    $1,695,000
    4,257 SF
    Versatile Office Condo in Naples

    Centrally located office condo with flexible space and ample parking.

    103-3021 Airport Rd N, Naples, FL 34104

    View details
    Move-in Ready Medical Office Condo
    $950,000
    1,993 SF
    Move-in Ready Medical Office Condo

    1,993 SF medical office condo in North Naples.

    1217 Piper Boulevard, Naples, FL 34119

    View details
    Medical Office Condo For Sale
    $2,600,000
    5,471 SF
    Medical Office Condo For Sale

    Medical office condo in Vanderbilt Galleria, fully leased.

    9125 Corsea Del Fontana Way, Naples, FL 34109

    View details
    Medical Office Condos For Sale
    $4,600,000
    7,971 SF
    Medical Office Condos For Sale

    Class A medical office condos in prime North Naples location.

    2350 Vanderbilt Beach Rd, Naples, FL

    View details
    Remodeled Medical Office Condominium
    $1,329,000
    2,410 SF
    Remodeled Medical Office Condominium

    Move-in-ready, renovated medical office in desirable Naples corridor.

    1575 Pine Ridge Rd Suite 19, Naples, FL 34109

    View details
    Built-Out Ambulatory Surgery Center
    $2,450,000
    3,200 SF
    Built-Out Ambulatory Surgery Center

    Ambulatory Surgery Center with supporting administration area for sale.

    130 9th St N Suite 250, Naples, FL 34102

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    WINTER PARK Land Lease Opportunity
    $8,500/Mo
    23,056 SF

    WINTER PARK Land Lease Opportunity

    Commercial land lease opportunity in Winter Park, Florida.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details
    Prime Commercial Lot For Rent
    $7,500/Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Prime Development Opportunity in Greenville
    Contact for pricing

    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607
    View details

    Naples, FL Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Naples, FL with 16 listings featured on our commercial real estate exchange. The current inventory includes 96,432 square feet of properties with an estimated lease value of $128 SF/Yr.

    Estimated lease rates for Medical Office Space in Naples, FL begin at $20 SF/Yr, with an average of $25 SF/Yr and extend to $35 SF/Yr.
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    Most Searched ZIP Codes in Naples, FL

    • 34108
    • 34102
    • 34113
    • 34103
    • 34109
    • 34110

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