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Santa Ana, CA Medical Office Space for Lease

8 results

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Premier Medical/Professional Office Building

$2.00 SF/Yr

107,190 SF

Premier Medical/Professional Office Building

1600 N Broadway, Santa Ana, CA 92701

Renovated medical and professional office building with modern amenities.

Complete renovation planned to create a state‑of‑the‑art medical and professional office building.
Prime location in the heart of Orange County with easy access to the 5 and 55 Freeways.
Abundant free structured parking.
Approximately 50% of the building allocated for build‑to‑suit medical office suites.
Enjoy floor‑to‑ceiling windows with panoramic views.

Updated: Nov 21, 2025

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$2 SF/Yr

63,006 SF

Medical/Office Suites Near Hospitals

1401 N Tustin Avenue, Santa Ana, CA 92705

Three-story building with medical and office suites near freeways.

Centrally located near Orange Coast Hospital and Western Medical Center.
Elevator served freestanding building with medical and office suites available.
Free surface and in‑common parking.
Nets $0.15 PSF (includes utilities).
Medical and office suites available.

Updated: Jan 26

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$1.75 SF/Yr

59,590 SF

Professional Office Space Available

Professional office, medical, or dental spaces available near freeways.

1403 N Tustin Avenue, Santa Ana, CA 92705

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$1.75 SF/Yr

1403 N Tustin Avenue

Professional office space

1403 N Tustin Avenue Santa Ana, CA 92705, Santa Ana, CA 92705

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1,300 SF

Medical Office Space Available

1,300 SF medical office space for rent.

2010 E 1st St, Santa Ana, CA 92705

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$30 SF/Yr

1401 N Tustin Ave

1,400 SF of Office/Medical Space Available in Santa Ana, CA 92705

1401 N Tustin Ave, Santa Ana, CA 92705, Santa Ana, CA 92705

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38,316 SF

Santa Ana Mixed-Use Medical Building

Mixed-use medical office building in Santa Ana, California.

1570 Brookhollow Dr, Santa Ana, CA 92705

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1,200 SF

High-Visibility Corner Retail Space

Prime retail space with strong traffic and diverse tenant synergy.

2600 S Bristol St, Santa Ana, CA 92704

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Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 8 Active listings in Santa Ana, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

Explore Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

$4,500 /Mo

2,692 SF

Orange, CA Commercial Lease Opportunity

Classic building near the Plaza, suitable for medical or office use.

601 E Chapman Avenue, Orange, CA 92866

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$3 SF/Yr

17,594 SF

Medical Suites Available For Rent

Multi-tenant medical center with suites available in Tustin, CA.

17400 Irvine Blvd., Tustin, CA 92780

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2,853 SF

Medical Office Space Available

Medical office space for rent in shell condition, build to suit.

1031 W Chapman Ave, Orange, CA 92868

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Medical Office Space Near Hospital

Medical office space with easy access to freeways and hospital.

14642 Newport Ave, Tustin, CA 92780

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Explore Similar Spaces for Sale in Santa Ana, CA

Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

$1,250,000

2,494 SF

Santa Ana Medical Office Building

Commercial medical office building in Santa Ana, California for sale.

1126 N Flower Street, Santa Ana, CA 92703

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Santa Ana Commercial Building Opportunity

$4,295,000

16,290 SF

Santa Ana Commercial Building Opportunity

Freestanding commercial building on a large lot in Santa Ana.

2215 N Broadway, Santa Ana, CA 92706

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Mixed-Use Building in Downtown Santa Ana

$2,240,000

16,320 SF

Mixed-Use Building in Downtown Santa Ana

High-visibility mixed-use property in downtown Santa Ana.

503 N Main St, Santa Ana, CA 92701

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Contact for pricing

Versatile Commercial Property in Santa Ana

Santa Ana property suitable for retail, office, medical, and more.

1104 W 17th St, Santa Ana, CA 92706

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Freestanding Office/Medical Building For Sale

$995,000

1,614 SF

Freestanding Office/Medical Building For Sale

Freestanding building suitable for office or medical use.

1902 S Standard Avenue, Santa Ana, CA 92707

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$1,495,000

1,274 SF

Santa Ana Retail/Medical Building

Freestanding retail or medical office building for sale.

1718 N Fairview St, Santa Ana, CA

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

$9,656 /Mo

Grand Junction Commercial Land Lease

0.74 acre commercial land for lease in Grand Junction.

Highway 6&50, Grand Junction, CO 81505

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$17,728 /Mo

Grand Junction Commercial Land Opportunity

1.36 acre commercial land for lease in Grand Junction.

Sanford Drive, Grand Junction, CO 81505

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$3,600 /Mo

El Paso Commercial Land Lease

Commercial land for lease in a strategic El Paso location.

5538 E Paisano Drive, El Paso, TX 79905

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$6,500 /Mo

1,875 SF

Highway 72 Corner Lot

1.6 acre commercial lot for rent on Highway 72.

30472 Highway 72, Madison, AL 35756

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Santa Ana, CA Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Santa Ana, CA with 8 listings featured on our commercial real estate exchange. The current inventory includes 684,109,800 square feet of properties with an estimated lease value of $52 SF/Yr.

Estimated lease rates for Medical Office Space in Santa Ana, CA begin at $22 SF/Yr, with an average of $26 SF/Yr and extend to $30 SF/Yr.

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Santa Ana, CA Medical Office Space for Lease