For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Medical Space
1
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
  • Hospitality
  • Sports & Entertainment
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

Costa Mesa, CA Medical Office Space for Lease

8 results
List
Map
Medical Office Space in Costa Mesa
$7,024 / Mo

Medical Office Space in Costa Mesa

3151 Airway Ave, Costa Mesa, CA 92626

Professional medical/office building near Irvine, suitable for various specialties.

  • Prime medical office space in a well‑maintained building near Irvine.
  • Suitable for a wide range of medical specialties (e.g., Dermatology, Psychiatry, Chiropractic, Ophthalmology).
  • Opportunity to own or lease.
  • Clean, modern environment.
  • Exceptional property management.
View details
Medical Office Space Available
$2 SF/Yr
1,370 SF

Medical Office Space Available

3140 Red Hill Ave, Costa Mesa, CA 92626

Medical office space featuring multiple exam rooms, available 1/1/2026.

  • Four Exam Rooms for patient care
  • Reception and Waiting Area for greeting clients
  • Private Doctor's Office, a dedicated workspace
  • Kitchenette included
  • Storage Space available
View details
Office/Medical Space Available For Rent
$6,499,000
5,950 SF

Office/Medical Space Available For Rent

Second floor office/medical space available for rent.

1120 Bristol St, Costa Mesa, CA 92626
View details
Costa Mesa Office/Medical Building
$2 SF/Yr
140,098 SF

Costa Mesa Office/Medical Building

Office and medical suites available in Costa Mesa, CA.

1901 Newport Blvd, Costa Mesa, CA 92626
View details
Freestanding Office Building For Lease
Contact for pricing
3,350 SF

Freestanding Office Building For Lease

Two-story office building suitable for medical or traditional office use.

2314 Newport Blvd, Costa Mesa, CA 92627
View details
Costa Mesa Office Space Available
$11 SF/Yr
6,549 SF

Costa Mesa Office Space Available

Flexible workspace solutions in Orange County.

3330 Harbor Blvd, Costa Mesa, CA 92626
View details
Costa Mesa Office Space for Lease
$12 SF/Yr
4,629 SF

Costa Mesa Office Space for Lease

Flexible workspace solutions in Orange County.

3420 Bristol St, Costa Mesa, CA 92626
View details
Pacific Medical Plaza: Costa Mesa
Contact for pricing
15,402 SF

Pacific Medical Plaza: Costa Mesa

Medical Office Space Available; Prime Location

1640 Newport Blvd, Costa Mesa, CA 92627
View details
Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 8 Active listings in Costa Mesa, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

Explore Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Newport Beach Medical Office Space
Contact for pricing
75,000 SF

Newport Beach Medical Office Space

Class A Medical Office Suites Available

3300 Irvine Ave, Newport Beach, CA 92660
View details
Medical Office Suites For Lease
Contact for pricing
23,000 SF

Medical Office Suites For Lease

Medical office suites available from 1,750 to 23,000 SF.

20071 SW Birch St, Newport Beach, CA 92660
View details
Fountain Valley Medical Office Building
$25 SF/Yr
3,000 SF

Fountain Valley Medical Office Building

Prime Medical Office Space, Fountain Valley, CA

17971 Euclid St, Fountain Valley, CA 92708
View details
Medical Office Sublease Opportunity
Contact for pricing
2,957 SF

Medical Office Sublease Opportunity

First floor physical therapist office space for sublease.

10540 Talbert Ave, Fountain Valley, CA 92708
View details

Costa Mesa, CA Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Costa Mesa, CA with 8 listings featured on our commercial real estate exchange. The current inventory includes 6,649,259,760 square feet of properties with an estimated lease value of $28 SF/Yr.

Estimated lease rates for Medical Office Space in Costa Mesa, CA begin at $2 SF/Yr, with an average of $7 SF/Yr and extend to $12 SF/Yr.
List
Map