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    Palmetto, FL Commercial Real Estate for Lease

    12 results
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    Modern Office Suite on US-41
    $4,000 / Mo
    1,206 SF

    Modern Office Suite on US-41

    10305 Us Highway 41 N, Palmetto, FL 34221

    Turnkey 1,206 sq ft office suite in Palmetto, Florida.

    • Prime location on S Tamiami Trail (US‑41) with maximum visibility and easy access.
    • Turnkey, modern 1,206 sq. ft. office suite ready for immediate occupancy.
    • Features three large private offices, spacious reception area, private bathroom, and dedicated kitchen.
    • Strategically located 1.5 miles north of I‑275, providing easy access to St. Petersburg, Tampa, and Sarasota.
    • Ample parking for over 20 cars.
    Updated: Sep 29, 2025
    View details
    Retail Space Available for Lease
    $17 SF/Yr
    2,750 SF

    Retail Space Available for Lease

    937 10Th St E, Palmetto, FL 34221

    Retail/office space available for lease with great signage.

    • High‑visibility signage available on US 301/10th St pylon.
    • 2,750 SF +/- retail/office space.
    • Mostly open layout with one private office.
    • Handicap accessible restroom.
    • Breakroom area with sink.
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    Stand Alone Building For Lease
    $18 SF/Yr
    2,640 SF

    Stand Alone Building For Lease

    Stand-alone building suitable for office, medical, or retail use.

    1331 10Th St E, Palmetto, FL 34221
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    Retail Space in Palmetto, FL
    $25 SF/Yr
    4,400 SF

    Retail Space in Palmetto, FL

    Freestanding retail building in a high-traffic area for lease.

    1210 St E, Palmetto, FL
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    Versatile Retail and Office Center
    Contact for pricing
    1,700 SF

    Versatile Retail and Office Center

    Retail and office center in downtown Palmetto, near Manatee River.

    701 8Th Ave W, Palmetto, FL 34221
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    Resort Retail Space Available
    Contact for pricing
    2,035 SF

    Resort Retail Space Available

    Retail spaces and pads for lease in Marriott Resort Hotel.

    650 Us Highway 41 N, Palmetto, FL 34221
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    Resort Retail Space Available
    Contact for pricing
    6,500 SF

    Resort Retail Space Available

    Retail spaces and pads for lease in Marriott Resort Hotel.

    600 Us Highway 41 N, Palmetto, FL 34221
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    Palmetto Industrial Land with Canopy
    $5,000 / Mo
    1,600 SF

    Palmetto Industrial Land with Canopy

    Industrial land with canopy and modular office for lease.

    1908 13Th St E, Palmetto, FL 34221
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    Palmetto Office Space Sublease Available
    $18 SF/Yr
    3,450 SF

    Palmetto Office Space Sublease Available

    Modern Office Suite, 3450 sq ft, Immediate Occupancy

    2510 51St Ave, Palmetto, FL 34221
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    Palmetto Retail Space For Lease
    $25 SF/Yr
    4,400 SF

    Palmetto Retail Space For Lease

    Prime location, high traffic, 4,400 sq ft.

    1210 10Th St, Palmetto, FL 34221
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    Palmetto Waterfront Office Space
    $48 SF/Yr
    16,822 SF

    Palmetto Waterfront Office Space

    Prestigious riverfront office, stunning views.

    1001 Riverside Dr, Palmetto, FL 34221
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    Palmetto Industrial Space For Lease
    Contact for pricing
    160,563 SF

    Palmetto Industrial Space For Lease

    Modern 160,563 SF manufacturing/warehouse.

    920 17Th St, Palmetto, FL 34208
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    Based on your search, we've compiled 73 Potential Opportunities for your consideration. Besides 12 Active listings in Palmetto, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 57 Properties for Sales.

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Palmetto Industrial Park - Building 1
    Contact for pricing
    160,618 SF

    Palmetto Industrial Park - Building 1

    Modern Manufacturing Space Available

    810 17Th St, Bradenton, FL 34208
    View details
    Class A Riverfront Office Space
    Contact for pricing
    5,871 SF

    Class A Riverfront Office Space

    Premier office space with Manatee River views and convenient access.

    101 Riverfront Blvd, Bradenton, FL 34205
    View details
    Palmetto Industrial Park - Building 3
    Contact for pricing
    107,768 SF

    Palmetto Industrial Park - Building 3

    107,768 SF Manufacturing/Warehouse Space

    1110 17 St, Memphis, FL 34208
    View details
    Professional Office Building in Riverwalk
    Contact for pricing
    2,070 SF

    Professional Office Building in Riverwalk

    Well-maintained office building near Manatee Memorial Hospital.

    100 3Rd Ave W, Bradenton, FL 34205
    View details

    Explore Similar Spaces for Sale in Palmetto, FL

    Consider Similar Space for Sale. We found 57 Spaces in Nearby Locations matching your search parameters.

    High-Visibility Land on Moccasin Wallow
    $1,399,999
    2.49 Acres

    High-Visibility Land on Moccasin Wallow

    2.49 acre parcel with road frontage in rapidly growing area.

    2519 Moccasin Wallow Rd, Palmetto, FL 34221
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    High-Visibility Land on Moccasin Wallow
    $1,399,999
    2.49 Acres

    High-Visibility Land on Moccasin Wallow

    2.5 acre parcel with road frontage in rapidly growing area.

    2519 Moccasin Wallow Rd, Palmetto, FL 34221
    View details
    Equestrian Center with Mediterranean Home
    $1,500,000
    3,946 SF

    Equestrian Center with Mediterranean Home

    4.9-acre horse ranch with home, cabin, and 20-stall barn.

    9510 36Th Ave E, Palmetto, FL 34221
    View details
    Riviera Dunes Marina Slip Available
    $289,000
    0.03 Acres

    Riviera Dunes Marina Slip Available

    70' boat slip in a protected Florida marina.

    102 Riviera Dunes Way, Palmetto, FL 34221
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    Prime Commercial Land Near I-275
    $3,499,000
    7.61 Acres

    Prime Commercial Land Near I-275

    7.61 acres of commercial land with frontage on US Hwy 41N.

    7219 Us Highway 41, Palmetto, FL 34221
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    Expansive Land in Booming Palmetto
    $720,000
    11.52 Acres

    Expansive Land in Booming Palmetto

    Almost 12 acres in northern Manatee County, Florida.

    12870 Grass Farm Rd, Palmetto, FL 34221
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    Palmetto Medical Building on 2.24 Acres
    $2,790,000

    Palmetto Medical Building on 2.24 Acres

    Strategically located medical building with flexible space and expansion potential.

    602 4Th Avenue Blvd West, Palmetto, FL 34221
    View details
    Land with Development Potential
    Pending
    $530,000
    0.50 Acres

    Land with Development Potential

    Land with potential water views and development opportunities.

    336 W 10Th Ave, Palmetto, FL 34221
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    Riviera Dunes Marina North Dock
    $350,000

    Riviera Dunes Marina North Dock

    70' boat slip in Riviera Dunes Marina for sale.

    102 Riviera Dunes Way, Palmetto, FL 34221
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    25 Acres Interchange Opportunity
    $11,925,000

    25 Acres Interchange Opportunity

    25 acres with frontage on US-41 and I-275.

    7611 Us Highway 41 N, Palmetto, FL 34221
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    Manatee County Development Site
    $2,400,000

    Manatee County Development Site

    Commercial development site in a rapidly growing area.

    9750 Bud Rhoden Rd, Palmetto, FL 34221
    View details
    Prime Mixed-Use Development Site
    $3,500,000

    Prime Mixed-Use Development Site

    3.4-acre site in Palmetto, Florida, near Manatee River.

    834 Riverside Dr, Palmetto, FL 34221
    View details

    Palmetto, FL Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Palmetto, FL with 69 listings featured on our commercial real estate exchange. The current inventory includes 1,623,394,080 square feet of properties with an estimated lease value of $230 SF/Yr.

    Estimated lease rates for Commercial real estate in Palmetto, FL begin at $17 SF/Yr, with an average of $28 SF/Yr and extend to $48 SF/Yr.
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