Palmetto, FL Commercial real estate for Rent & Lease

Updated: May 3

Modern Office Suite with Private Offices

10305 US HIGHWAY 41 N, Palmetto, FL 34221

$4,000/Mo

11,345 sqft 8.64 AC lot

Three private offices plus a reception area
Private bathroom and dedicated kitchen
1,206 sq. ft. office suite with luxury vinyl flooring and modern lighting
Located 1.5 miles north of I‑275 along US‑41
On‑site parking for over 20 cars

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Updated: Jun 2

Office/Medical End Suite

1301 10th St E, Palmetto, FL 34221

$22 SF/Yr

850 sqft

850 SF professional office/medical suite in River North Business Center (Year built 1981)
End unit with abundant natural light from N, W & S exposure
Layout includes 2 private offices plus reception/lobby and open bullpen
Updated vinyl plank flooring throughout
Located on US 301 with ample on‑site parking

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High-Clearance Industrial Warehouse

1507 17th Street East, Palmetto, FL 34221

Contact for pricing

14,300 sqft 2.35 AC lot

LM zoning and multiple loading features define this industrial facility.

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High-Visibility Office/Retail Lease

701 8th Ave W, Palmetto, FL 34221

$20 SF/Yr

Street-front space in Palmetto designed for businesses seeking prominent exposure on a major downtown road.

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Distribution Center with Rear Loading

810 17th St E, Palmetto, FL 34221

Contact for pricing

20,000 sqft

Rear-loaded industrial space features ESFR fire protection and 1,600A, 277/480V, 3-phase power.

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Air-Conditioned Warehouse with Office

2225 S. Dock St., Palmetto, FL 34221

Contact for pricing

2,400 sqft

Fully air-conditioned 400 SF office plus 2,000 SF warehouse with a 12’ x 14’ overhead roll-up door.

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NNN Industrial Property

4106 US 41 N, Palmetto, FL 34221

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3,700 sqft 0.50 AC lot

An industrial building is leased under a new five-year NNN agreement.

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Resort Retail Spaces with Water Views

600 US Hwy 41 N, Palmetto, FL 34221

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3,400 sqft

Retail spaces and pads available in a resort setting with water views and high visibility for hotel guests.

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Resort Retail Space Available

650 US Hwy 41 N, Palmetto, FL

Contact for pricing

2,035 sqft 1.27 AC lot

Retail spaces and pads for lease in Marriott Resort Hotel.

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Corner Parcel Near Future Grocer

9620 36th Ave E, Palmetto, FL 34221

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Commercial land for rent near major roads and future development.

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Based on your search, we've compiled 74 Potential Opportunities for your consideration. Besides 10 Active listings in Palmetto, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 60 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Restaurant Space with Riverfront Views

100 Riverfront Boulevard, Bradenton, FL 34205

Contact for pricing

7,500 sqft

Existing restaurant improvements offer an established dining layout and potential outdoor service area.

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Office Building with Fenced Yard

7210 US 301 N, Ellenton, FL 34222

Contact for pricing

6,500 sqft

Two-parcel office property with month-to-month occupancy, executive suites, and a separate warehouse.

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Office Unit with Signage

7210 US 301 N, Ellenton, FL 34222

Contact for pricing

850 sqft

Available suite offers an open work area, private office, shared facilities, and prominent US 301 frontage.

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Class A Riverfront Office Space

101 Riverfront Blvd, Bradenton, FL 34205

$14.25 SF/Yr

Premier office space with Manatee River views and convenient access.

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Similar Spaces for Sale in Palmetto, FL

Consider Similar Space for Sale. We found 60 Spaces matching your search parameters.

Waterfront Restaurant Property

5611 US HIGHWAY 19, Palmetto, FL 34221

$2,200,000

5,247 sqft 0.84 AC lot

Restaurant property with bay frontage, outdoor gathering areas, and existing food-service infrastructure.

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Leased Medical Office with Exam Rooms

506 4TH Avenue W, Palmetto, FL 34221

$845,000

3,171 sqft 0.60 AC lot

A single-tenant medical practice occupies the property under a NNN lease with annual escalations and renewal options.

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Leased Medical Office Building

506 4TH AVENUE W, Palmetto, FL 34221

$845,000

3,213 sqft

Single-tenant medical office with a purpose-built clinical layout and recently installed HVAC systems.

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Waterfront Property on US 19

5611 US HIGHWAY 19, Palmetto, FL 34221

$2,200,000

5,247 sqft

Prime waterfront location with high traffic exposure on US 19.

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Net-Leased Tire Service Facility

1429 10th Street E, Palmetto, FL 34221

$1,600,000

8,400 sqft

Single-tenant Tire Kingdom property offered on a triple-net basis with an established automotive service operator.

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Wendy's Fast-Food Restaurant

606 10th St E, Palmetto, FL 34221

$8,171,427

2,695 sqft

Single Wendy's fast-food restaurant offered for sale with a franchise operator providing a personal guaranty on the lease.

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Palmetto Medical Building on 2.24 Acres

602 4th Avenue West, Palmetto, FL 34221

$2,000,000

16,382 sqft 2.24 AC lot

Strategically located medical building with flexible space and expansion potential.

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Industrial Land with Storage Yard

2103 & 2125 17th St E, Palmetto, FL 34221

$2,800,000

4,000 sqft 4.78 AC lot

Two contiguous industrial parcels include fenced outdoor storage, a concrete slab, and a 5,000-square-foot building package.

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Specialty Villa with Screened Lanai

5403 RUSHMERE COURT, Palmetto, FL 34221

$390,000

1,582 sqft

The 2021 residence offers an open living area, a dedicated laundry room, and an attached garage.

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High-Visibility Land on Moccasin Wallow

2519 Moccasin Wallow Rd, Palmetto, FL 34221

$1,199,999

1,080 sqft 2.50 AC lot

2.5 acre parcel with road frontage in rapidly growing area.

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Waterfront Marina with Dry Storage

6817 Bayshore Road, Palmetto, FL 34221

$5,495,000

1,538 sqft 10.32 AC lot

Operating marine property with wet slips, boat ramp, clubhouse, and protected access to regional waterways.

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Industrial Assemblage with Storage Yard

2103 & 2125 17TH STREET E, Palmetto, FL 34221

$2,800,000

4.78 AC lot

Two contiguous industrial parcels combine outdoor storage operations, a telecommunications lease, and existing site improvements.

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Waterfront Marina with Wet Slips

6817 Bayshore Rd, Palmetto, FL 34221

$5,495,000

3,287 sqft

Operating marine property with a protected basin, boat ramp, dry storage, workshop, and air-conditioned clubhouse.

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Verizon NNN Property

9690 Buffalo Road, Palmetto, FL 34221

Contact for pricing

2,464 sqft 0.48 AC lot

Verizon-branded retail property with a planned modified NNN lease structure.

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