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    Palmetto, FL
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    Palmetto, FL Office Spaces for Lease

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    Bradenton, FL Sarasota, FL Bradenton Beach, FL
    Modern Office Suite on US-41
    $4,000/Mo
    11,345 SF
    Modern Office Suite on US-41

    10305 US HIGHWAY 41 N, Palmetto, FL 34221

    Turnkey office suite with modern finishes and excellent location.
    • Prime location on S Tamiami Trail (US‑41) with high visibility and easy access.
    • Turnkey, modern 1,206 sq. ft. office suite ready for immediate occupancy.
    • Three large private offices, spacious reception area, private bathroom, and dedicated kitchen.
    • Strategically located 1.5 miles north of I‑275, providing easy access to St. Petersburg, Tampa, and Sarasota.
    • High‑standard finishes including luxury vinyl flooring, modern lighting, and large windows with privacy treatments.
    Updated: May 3
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    Stand Alone Building For Lease
    $18 SF/Yr
    2,640 SF
    Stand Alone Building For Lease

    1331 10th St E, Palmetto, FL

    Stand-alone building suitable for office, medical, or retail use.
    • Stand‑alone building: Only stand‑alone building in River North Business Center.
    • Flexible zoning: CG zoning designation suitable for office, medical, or retail use.
    • Ample parking: Abundance of parking spaces available for customers and employees.
    • Functional floorplan: Includes 10 private offices, reception area, open area, kitchenette, and 2 handicap restrooms.
    • Strategic location: Located between US 41/Business 41 and I‑75, with easy access to I‑275.
    Updated: Oct 28, 2025
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    Retail/Office Unit on 8th Avenue
    $2.00 SF/Yr
    Retail/Office Unit on 8th Avenue

    Highly visible retail/office unit with front and rear access.

    835 8TH Ave W, Palmetto, FL 34221

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    Renovated Building on US41/US19 Interchange
    Contact for pricing
    Renovated Building on US41/US19 Interchange

    Modernized freestanding building suitable for retail, restaurant, or offices.

    3966 U.S. 41, Palmetto, FL

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    Palmetto Retail/Flex Space Available
    Contact for pricing
    2,240 SF
    Palmetto Retail/Flex Space Available

    Versatile 2,240 SF retail/flex space in Palmetto, Florida.

    925 10th St E, Palmetto, FL 34221

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    Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 5 Active listings in Palmetto, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 11 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Space Near Hospital
    $24 SF/Yr
    900 SF
    Medical Office Space Near Hospital

    Medical office suites available near Manatee Memorial Hospital in Bradenton.

    201 4th Ave E, Bradenton, FL 34208

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    Class A Riverfront Office Space
    $14 SF/Yr
    5,871 SF
    Class A Riverfront Office Space

    Premier office space with Manatee River views and convenient access.

    101 Riverfront Blvd, Bradenton, FL

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    Professional Office Building in Riverwalk
    Contact for pricing
    2,070 SF
    Professional Office Building in Riverwalk

    Well-maintained office building near Manatee Memorial Hospital.

    100 3rd Ave W, Bradenton, FL

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    Professional Office Building in Riverwalk
    Contact for pricing
    Professional Office Building in Riverwalk

    Well-maintained office building near Manatee Memorial Hospital and downtown Bradenton.

    100 3rd Avenue W., Bradenton, FL 34205

    View details

    Similar Spaces for Sale in Palmetto, FL

    Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

    High-Visibility Land Parcel on Moccasin
    $1,299,999
    1,080 SF
    High-Visibility Land Parcel on Moccasin

    Prime ~2 acre parcel with road frontage in rapidly growing area.

    2519 MOCCASIN WALLOW ROAD, Palmetto, FL 34221

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    Palmetto Medical Building on 2.24 Acres
    $2,790,000
    16,382 SF
    Palmetto Medical Building on 2.24 Acres

    Strategically located medical building with flexible space and expansion potential.

    602 4th Avenue West, Palmetto, FL 34221

    View details
    Downtown Palmetto Commercial Property
    $699,000
    4,600 SF
    Downtown Palmetto Commercial Property

    Two-story commercial property with retail and office space.

    435 10th Ave W, Palmetto, FL

    View details
    High-Visibility Land on Moccasin Wallow
    $1,399,999
    1,080 SF
    High-Visibility Land on Moccasin Wallow

    2.5 acre parcel with road frontage in rapidly growing area.

    2519 MOCCASIN WALLOW ROAD, Palmetto, FL 34221

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    High-Visibility Land on Moccasin Wallow
    $1,399,999
    2.49 Acres
    High-Visibility Land on Moccasin Wallow

    Prime ~2.5 acre parcel with road frontage in growing Parrish.

    2519 MOCCASIN WALLOW ROAD, Palmetto, FL 34221

    View details
    Palmetto Tower with Redevelopment Potential
    $6,000,000
    63,188 SF
    Palmetto Tower with Redevelopment Potential

    Multi-story office building with vacant lots in downtown Palmetto.

    600 W 8TH AVE, Palmetto, FL

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    Free-Standing Industrial Facility For Sale
    $2,351,250
    12,375 SF
    Free-Standing Industrial Facility For Sale

    12,375 SF vacant industrial facility with showroom and warehouse space.

    1610 12th St E, Palmetto, FL 34221

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    Versatile Retail and Office Center
    $1,750,000
    Versatile Retail and Office Center

    Retail and office center in downtown Palmetto near Manatee River.

    701 8th Avenue W., Palmetto, FL 34221

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    Versatile Retail and Office Center
    $1,750,000
    1,700 SF
    Versatile Retail and Office Center

    Retail and office center in downtown Palmetto, near Manatee River.

    701 8th Ave W, Palmetto, FL

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    Palmetto Mixed-Use Development Opportunity
    $3,500,000
    3.40 Acres
    Palmetto Mixed-Use Development Opportunity

    Development site near Manatee River suitable for mixed-use projects.

    834 RIVERSIDE DRIVE, Palmetto, FL 34221

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    Palmetto 52-Acre Assemblage Opportunity
    $10,500,000
    16,443 SF
    Palmetto 52-Acre Assemblage Opportunity

    52 acres with buildings, prime location, development potential.

    1321 77th St E, Palmetto, FL 34221

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land Near Shopping
    $21,000 SF/Yr
    200,000 SF
    Commercial Land Near Shopping

    Commercial land for rent, conveniently located near shopping.

    6012 LORRAINE ROAD, Bradenton, FL 34211

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    Commercial Lot on Franklin Avenue
    Contact for pricing
    10,203 SF
    Commercial Lot on Franklin Avenue

    Commercial lot zoned CG, great location for various businesses.

    16220 Franklin Avenue, Port Charlotte, FL 33953

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    Lakeland Commercial Business Park Spaces
    Contact for pricing
    Lakeland Commercial Business Park Spaces

    Commercial spaces for lease in West Lakeland business park.

    2525 Drane Field Road, Lakeland, FL 33811

    View details
    Downtown Winter Haven Commercial Land
    $29,940 SF/Yr
    Downtown Winter Haven Commercial Land

    City-approved commercial land in a growing business district.

    511 AVENUE G NW, Winter Haven, FL 33881

    View details

    Palmetto, FL Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Palmetto, FL with 5 listings featured on our commercial real estate exchange. The current inventory includes 13,985 square feet of properties with an estimated lease value of $22 SF/Yr.

    Estimated lease rates for Office Spaces in Palmetto, FL begin at $4 SF/Yr, with an average of $11 SF/Yr and extend to $18 SF/Yr.
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