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Mission Street Commercial Property

4494 Mission Street, San Francisco, CA 94132

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For Sale

$1,150,000

2,500 SF commercial property in the Excelsior District.

Type:Commercial

Property size:

2,495 SF

Lot size:

0.06 Acres

Price / SF:

$460/SF

HighLights

Prime corner location on Mission Street in the Excelsior District with high foot traffic
Zoned NCD‑Excelsior with potential for development of up to 10 units and over 9,500 sq/ft of buildable space (feasibility study available)
2,500 sq/ft commercial property with open floor plan (1,300 sq/ft ground floor including garage, 525 sq/ft mezzanine)
Two‑car parking with separate garages accessible from Santa Rosa Avenue
Prominent street frontage
Historical significance as the former home of 'Central Drug Store' for 116 years

We can help!

Listing Contact

JOHN M ANTONINI

For Sale

$1,150,000

2,500 SF commercial property in the Excelsior District.

Type:Commercial

Property size:

2,495 SF

Lot size:

0.06 Acres

Price / SF:

$460/SF

Added:: Mar 27, 2026
Days on Market:: 75
Last Refresh:: Mar 27 at 8:09 pm

Property Features for 4494 Mission Street

General Information

Standard status: Active
Size: 2,495 SF
Lot size: 0.06 Acres
Property subtype: Commercial

Building Details

Year Built: 1910

We can help!

Listing Contact

JOHN M ANTONINI

Listing agent JOHN M ANTONINI

Listing office COMPASS COMMERCIAL

Listing date Mar 27, 2026

Source Corcoran

Displayed information is deemed reliable but is not guaranteed and should be independently verified.

All listing content including descriptions, pricing, images are the copyrighted material of COMPASS COMMERCIAL

HighLights

Prime corner location on Mission Street in the Excelsior District with high foot traffic
Zoned NCD‑Excelsior with potential for development of up to 10 units and over 9,500 sq/ft of buildable space (feasibility study available)
2,500 sq/ft commercial property with open floor plan (1,300 sq/ft ground floor including garage, 525 sq/ft mezzanine)
Two‑car parking with separate garages accessible from Santa Rosa Avenue
Prominent street frontage
Historical significance as the former home of 'Central Drug Store' for 116 years

Overview

The property at 4494 Mission Street offers 2,500 square feet of commercial space with two-car parking. Formerly the site of 'Central Drug Store' for 116 years, operated by the same family for over 60 years before closing in 2025, this property is located on the corner of Mission Street and Santa Rosa Avenue in the Excelsior district, benefiting from prominent street frontage and substantial foot traffic. The building features an open floor plan with approximately 1,300 square feet on the ground floor, including a garage, plus a 525 square foot mezzanine and approximately 10-foot ceilings. Two separate garages are accessible from Santa Rosa Avenue. Zoned NCD-Excelsior, a feasibility study suggests potential for development of up to 10 units and over 9,500 square feet of buildable space. The property is suited for a new owner to start a legacy project in the Excelsior District.

Property Profile Location Intelligence

Current Use by Public Records

Central Drug Store Pharmacy

Suggested Use

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Location Insight

Map
Local Demand

City: San Francisco
County: San Mateo
State: California
Longitude: -122.434451
Latitude: 37.725628

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For sale
Storefront properties
CA
San Francisco
94132
4494 Mission Street

What type of property is this?

Storefront property - 2,500 SF commercial property in the Excelsior District.

Where is this storefront property located?

The property is located at 4494 Mission Street San Francisco, CA.

What is the asking price?

The asking price for this property is $1,150,000.

What are key features of this property?

This property features: Prime corner location on Mission Street in the Excelsior District with high foot traffic; Zoned NCD‑Excelsior with potential for development of up to 10 units and over 9,500 sq/ft of buildable space (feasibility study available); 2,500 sq/ft commercial property with open floor plan (1,300 sq/ft ground floor including garage, 525 sq/ft mezzanine)