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    Des Moines, IA Commercial Real Estate for Sale

    208 results
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    Adaptable Commercial Space, Des Moines/Ankeny
    $950,000
    1.86 Acres

    Adaptable Commercial Space, Des Moines/Ankeny

    1380 NE 66th Avenue, Des Moines, IA 50313

    Renovated commercial space suitable for retail, office, or service businesses.

    • Extensively renovated in 2017 with modern finishes and updated systems.
    • Highly adaptable layout suitable for retail, office, studio, or service‑oriented businesses.
    • Prime location on NE 66th Avenue in the Des Moines/Ankeny corridor with convenient access and visibility.
    • Recent addition in 2024 enhances functionality and square footage.
    • Move‑in‑ready condition, ideal for immediate occupancy and operation.
    Updated: Jan 26
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    Automotive Shop in Des Moines
    $315,000
    0.16 Acres

    Automotive Shop in Des Moines

    1501 6th Avenue, Des Moines, IA 50314

    Fully functioning automotive shop in a high-traffic location.

    • Optimal location with high daily traffic for high exposure.
    • Fully functioning automotive shop.
    • Car lift conveys with the property.
    • Potential to convert to a different business.
    • Constructed with durable brick and block materials.
    Updated: Nov 10, 2025
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    Des Moines Development Opportunity
    $300,000
    1.92 Acres

    Des Moines Development Opportunity

    1.92 acres of land zoned RX1 in Des Moines.

    3101 SE 22nd Street, Des Moines, IA 50320
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    Historic Mixed-Use Property For Sale
    $225,000
    3,550 SF

    Historic Mixed-Use Property For Sale

    Unique mixed-use property with commercial space and residential apartments.

    3516 SW 9th Street, Des Moines, IA 50315
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    Des Moines Duplex: Investment Opportunity
    $195,000
    1,282 SF

    Des Moines Duplex: Investment Opportunity

    Charming Des Moines duplex, ideal for investors or homeowners.

    1442 34th Street, Des Moines, IA 50311
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    Commercial Land Near DSM Airport
    $499,000
    1.42 Acres

    Commercial Land Near DSM Airport

    Ideal commercial location across from Des Moines Airport.

    2501 Mckinley Avenue, Des Moines, IA 50321
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    Des Moines Retail Property For Sale
    $1,600,000
    1.09 Acres

    Des Moines Retail Property For Sale

    Retail property available for sale in Des Moines, Iowa.

    606 E Army Post Road, Des Moines, IA 50315
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    Retail Center in Beaverdale Neighborhood
    $915,000
    8,600 SF

    Retail Center in Beaverdale Neighborhood

    Established retail center in Des Moines' desirable Beaverdale neighborhood.

    3708 Beaver Avenue, Des Moines, IA 50310
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    Des Moines Flex/Industrial Building
    $675,000
    8,112 SF

    Des Moines Flex/Industrial Building

    Well-maintained flex building with warehouse and office space for sale.

    1429 2nd Avenue, Des Moines, IA 50314
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    Ocean-View Development Land in Ostional
    $2,000,000

    Ocean-View Development Land in Ostional

    19.84-acre development land with ocean views, subdivided into 20 lots.

    Des Moines, 50309
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    Des Moines Land Opportunity
    $149,950
    2.49 Acres

    Des Moines Land Opportunity

    2.49-acre parcel with potential for high-density residential conversion.

    2009-2013 Martin Luther King Jr Parkway, Des Moines, IA 50314
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    Luxury Villas Near Costa Rica Beach
    $799,000
    2,691 SF

    Luxury Villas Near Costa Rica Beach

    Boutique villas, walk to beach, income potential.

    Des Moines, 50308
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    Two-Story Office Building For Sale
    $300,000
    1,872 SF

    Two-Story Office Building For Sale

    1,872 SF office building with partially finished basement.

    3161 Southeast 22nd Street, Des Moines, IA 50320
    View details
    Retail Space in Harding Hills
    $975,000
    12,220 SF

    Retail Space in Harding Hills

    Junior anchor space available for sale or lease.

    3430 Martin Luther King Jr Pkwy, Des Moines, IA
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    Profitable ATV Tour Business Opportunity
    $200,000

    Profitable ATV Tour Business Opportunity

    Turnkey ATV tour business for sale in Tamarindo, Costa Rica.

    Des Moines, 50309
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    Des Moines Commercial Corridor Property
    $550,000

    Des Moines Commercial Corridor Property

    Well-maintained property in accessible commercial corridor, ideal for various businesses.

    3508 Delaware Ave, Des Moines, IA 50313
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    Retail Property in Capitol East
    $725,000
    3,168 SF

    Retail Property in Capitol East

    Retail space with high visibility in Capitol East neighborhood.

    521 East 14th Street, Des Moines, IA 50316
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    Versatile Des Moines Commercial Building
    $2,133,600
    17,780 SF

    Versatile Des Moines Commercial Building

    17,780 SF building with office, shop, and warehouse space.

    1536 E Army Post Rd, Des Moines, IA 50320
    View details
    Des Moines Office Building For Sale
    $389,000
    2,152 SF

    Des Moines Office Building For Sale

    Two-story office building near Des Moines VA Medical Center.

    3811 38th St., Des Moines, IA 50310
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    Des Moines Commercial Development Land
    $300,000

    Des Moines Commercial Development Land

    Commercial development land for sale in Des Moines, Iowa.

    1475 Hart Avenue, Des Moines, IA 50320
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    Freestanding Retail Building For Sale
    $750,000

    Freestanding Retail Building For Sale

    Freestanding retail building in a mixed-use neighborhood.

    4931 Douglas Ave, Des Moines, IA 50310
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    Des Moines Commercial Corridor Property
    $600,000
    2,507 SF

    Des Moines Commercial Corridor Property

    Well-maintained property in accessible commercial corridor with high visibility.

    3508 Delaware Ave, Des Moines, IA 50313
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    Army Post Road Commercial Building
    $385,000
    5,377 SF

    Army Post Road Commercial Building

    Commercial building on Army Post Road with showroom and office space.

    1202 Army Post Rd, Des Moines, IA
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    Mixed-Use Property Near Grandview University
    $286,000
    3,683 SF

    Mixed-Use Property Near Grandview University

    High-visibility mixed-use property in a primary commercial corridor.

    3001 E 14th St, Des Moines, IA 50316
    View details

    Des Moines, IA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 208 commercial real estate for sale in Des Moines, IA, showcased through 208 active listings on our real estate platform. These investment opportunities span a total of 4,181,990 square feet of properties for sale, with an estimated market value of $19,206,220.

    Sale prices for business properties in Des Moines, IA start at $149,950, averaging $1,280,414, and reaching up to $5,890,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Commercial real estate for Sale Near Des Moines, IA

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    Most Searched ZIP Codes in Des Moines, IA

    • 50309
    • 50313
    • 50310
    • 50321
    • 50314
    • 50315
    • 50317
    • 50320
    • 50316
    • 50312
    • 50311

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