Anderson, SC Commercial Real Estate for Sale

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Versatile Property Near AnMed Hospital
Updated: Mar 6
Versatile Property Near AnMed Hospital

1502 E Greenville St, Anderson, SC 29621

$925,000
4,300 sqft 0.61 AC lot
High traffic count: 29,200 vehicles per day on E. Greenville St.
Excellent accessibility with access to a signalized intersection.
Versatile property suitable for office or retail redevelopment.
Strategic location: equidistant (1.5 miles) between AnMed Hospital and AnMed Health Campus.
Building size: 4,300 SF.
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1502 E Greenville St, Anderson, SC 29621

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Highway Commercial Property Near Development
Updated: Apr 28
Highway Commercial Property Near Development

4341 S Carolina 24, Anderson, SC 29626

$825,000
5,000 sqft 1.14 AC lot
Prime location on Hwy 24 in a growing commercial area with high development potential.
C‑2 (Highway Commercial District) zoning allows for a variety of commercial uses.
5,000 sq ft industrial building on 1.14 acres with potential for expansion.
Features 3‑phase electrical power.
Located in an unincorporated area of Anderson County.
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Flex-Use Retail and Office Building
Flex-Use Retail and Office Building

1804 S McDuffie Street, Anderson, SC 29624

$255,000
0.28 AC lot

Fully fenced flex-use building with an oversized side-entry garage and heated main space for retail, office, or dining concepts.

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Commercial Property Near Downtown Anderson
Commercial Property Near Downtown Anderson

3499 East River Street, Anderson, SC 29621

$429,000
2,430 sqft 0.64 AC lot

Well-maintained flex building with office and warehouse space.

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Highway-Front Buildable Lot
Highway-Front Buildable Lot

120 Perpetual Square, Anderson, SC 29621

$770,000
1.50 AC lot

Buildable commercial land on Highway 81 North, well suited for a medical office or other purpose-built development.

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Two-Story Retail and Office Plaza
Two-Story Retail and Office Plaza

2406, 2408, 2410 N Main Street, Anderson, SC 29621

$1,990,000

Two-story plaza with 12 shop and office units plus a rear entrance for added tenant access flexibility.

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Retail Building on Miracle Mile
Retail Building on Miracle Mile

110 Miracle Mile Drive, Anderson, SC 29621

$3,900,000
2.76 AC lot

Prime retail building with excellent visibility and accessibility in Anderson.

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Office Building with Off-Street Parking
Office Building with Off-Street Parking

2006 N Main Street, Anderson, SC 29621

$499,000
0.25 AC lot

Office building with paved front and rear parking, multiple entrances, and hard-surface flooring throughout the main level.

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9.8 Acres Commercial Land Anderson
9.8 Acres Commercial Land Anderson

Pearman Dairy Road, Anderson, SC 29625

$649,000
9.80 AC lot

9.8 acres of commercial land in high-visibility Anderson location.

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Anderson Commercial Property with Garage
Anderson Commercial Property with Garage

609 Fair Street, Anderson, SC 29625

$435,000
3,000 sqft 0.32 AC lot

Commercial property with a home and a fully functional garage.

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Prime Commercial Land I-85 Frontage
Prime Commercial Land I-85 Frontage

105 Destination Boulevard, Anderson, SC 29621

$949,000
1.80 AC lot

High-traffic commercial land with I-85 frontage in Anderson, SC.

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Cleared Commercial Development Land
Cleared Commercial Development Land

222 Brown Road, Anderson, SC 29621

$795,000

Cleared commercial land offered for sale, providing a blank site for a range of retail and restaurant concepts.

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Warehouse & Flex Space Facility
Warehouse & Flex Space Facility

109 Waybrook Drive, Anderson, SC 29624

$425,000
3.11 AC lot

Clear-span warehouse with flex-style potential, roll-up loading, and commercial/industrial zoning for a range of operations.

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Vacant Commercial Land Parcel
Vacant Commercial Land Parcel

1410 E Greenville Street, Anderson, SC 29621

$250,000
2.83 AC lot

Vacant commercial parcel on E Greenville Street with flexible development options and an available interest rate buy-down.

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Commercial Land in Anderson, SC
Commercial Land in Anderson, SC

R-1-B + R-2 Destination Boulevard, Anderson, SC 29621

$585,100
4.61 AC lot

4.61 acres of commercial land for sale.

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Multi-Office Building with Parking
Multi-Office Building with Parking

2006 N Main Street, Anderson, SC 29621

$499,000
0.25 AC lot

Office building with paved off-street parking and multiple entrances, including ramp access at the rear.

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Prime Land Near Technical College
Prime Land Near Technical College

321 Pearman Dairy Road, Anderson, SC 29625

$975,000
4.53 AC lot

4.53-acre commercial land with highway frontage near Tri-County Technical College.

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Commercial Land Parcel for Development
Commercial Land Parcel for Development

222 Brown Road, Anderson, SC 29621

$795,000
2.70 AC lot

2.7-acre commercial land parcel between Sam’s Club and Walmart entrances in Anderson, SC.

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Medical Office Suite in Professional Building
Medical Office Suite in Professional Building

400 N Fant Street, Anderson, SC 29621

$185,000

Suite A in a professional building with 7 total suites, featuring exam rooms, offices, a nurses’ station, and multiple restrooms.

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Turnkey Downtown Restaurant Building
Turnkey Downtown Restaurant Building

116 W Orr Street, Anderson, SC 29625

$2,250,000
0.38 AC lot

Renovated 1930-era restaurant space with covered outdoor dining, private parking, and multi-street access.

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Two-Building Office Property
Two-Building Office Property

4450 HIGHWAY 24, Anderson, SC 29626

$420,000
0.80 AC lot

Two-office building portfolio in Anderson, SC offered with possible owner financing terms.

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Commercial Land in Anderson, SC
Commercial Land in Anderson, SC

Tract 4 Highway 178, Anderson, SC 29621

$1,200,000
3.63 AC lot

3.63 acre commercial land with utilities in Anderson, SC.

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Prime Commercial Land For Sale
Prime Commercial Land For Sale

2205 Whitehall Road, Anderson, SC 29625

$295,900
2.08 AC lot

2.08 acre commercial land with high visibility and easy access.

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Prime Commercial Lot in Anderson
Prime Commercial Lot in Anderson

Whitehall Road, Anderson, SC 29625

$320,000
1.29 AC lot

High-traffic commercial lot offers unparalleled growth potential.

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Anderson, SC Commercial Real Estate Market Trends and Statistics

Explore 152 commercial real estate for sale in Anderson, SC, showcased through 152 active listings on our real estate platform. These investment opportunities span a total of 1,902,124 square feet of properties for sale, with an estimated market value of $48,310,715.

Sale prices for business properties in Anderson, SC start at $115,999, averaging $1,341,964, and reaching up to $7,060,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 100K
Population Growth (5Y) +0.7%
Median Household Income $59,984
College Educated 19.8%

High-Yield Neighborhoods for Investment

Identify Anderson submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
Anderson $817.8K
Townville $1M

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Anderson County

New Delisted

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in Anderson fall within the 100,000+ square foot range.

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