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    Holyoke, MA Healthcare Properties for Sale

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    Chicopee, MA South Hadley, MA West Springfield, MA
    Two-Building Campus on 8.19 Acres
    $2,290,000
    38,286 SF

    Two-Building Campus on 8.19 Acres

    1365-1375 Northampton Street, Holyoke, MA 1040

    Two-building campus on 8.19 acres near Interstate 91.

    • Two‑building campus with 44 rooms and 38 living quarters for diverse usage.
    • Located on 8.19 acres of private, nicely landscaped grounds.
    • Conveniently situated on Route 5, just 0.7 miles from Interstate 91 (Exit 15A), and on the PVTA bus route.
    • Ample on‑site parking available for 40+\/- vehicles.
    • Building 1 features 16 bedrooms, a chapel/meeting room, and multiple living spaces.
    Updated: Nov 21, 2025
    View details
    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 1 Active listings in Holyoke, MA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 11 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Established Hair and Beauty Salon
    $599,999

    Established Hair and Beauty Salon

    Upgraded hair and beauty salon with long-term lease in place.

    651 Enfield, Enfield, CT 6082
    View details
    Established Salon on High-Traffic Road
    $599,999
    3,170 SF

    Established Salon on High-Traffic Road

    Fully upgraded hair and beauty salon with long-term lease.

    651 Enfield Street, Enfield, CT 6082
    View details
    Turnkey Salon in Depot Village
    $169,900

    Turnkey Salon in Depot Village

    Established salon and day spa in Palmer's Depot Village.

    1581 N Main St, Palmer, MA 1069
    View details
    Depot Plaza Spa Opportunity
    $169,900

    Depot Plaza Spa Opportunity

    Spa and salon located in Depot Plaza.

    1581 N Main St, Palmer, MA 1069
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Amherst Developable Land Near Route 9
    $700,000
    4.51 Acres

    Amherst Developable Land Near Route 9

    4.5 acre parcel near Route 9, suitable for development.

    30 Greenleaves Drive, Amherst, MA 1002
    View details
    Amherst Developable Land Near Route 9
    $700,000
    4.51 Acres

    Amherst Developable Land Near Route 9

    4.5-acre parcel near Route 9, ideal for development.

    30 Greenleaves Dr, Amherst, MA 1002
    View details
    Amherst Developable Land Near Route 9
    $700,000
    4.51 Acres

    Amherst Developable Land Near Route 9

    4.5-acre parcel near Route 9, development opportunity.

    30 Greenleaves Dr, Amherst, MA 1002
    View details
    80+ Acres Raw Land
    $1,550,000
    83.12 Acres

    80+ Acres Raw Land

    80+ acres of raw land with development potential.

    Tolland Stage Road, Tolland, CT 06084
    View details

    Off-Market Properties in Holyoke, MA

    Consider similar Off-Market properties in Holyoke, MA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    35 Holy Family Rd

    35 Holy Family Rd

    HOMES (RETIRED, NURSING) • 61,085 SF
    Value Estimation
    $2,065,000
    35 Holy Family Rd, Holyoke, MA 01040-2701
    View details
    282 Cabot St

    282 Cabot St

    HOMES (RETIRED, NURSING) • 45,120 SF
    Value Estimation by Request
    282 Cabot St, Holyoke, MA 01040-3141
    View details
    279 Cabot St

    279 Cabot St

    HOMES (RETIRED, NURSING) • 17,435 SF
    Value Estimation by Request
    279 Cabot St, Holyoke, MA 01040-3139
    View details
    260 Easthampton Rd

    260 Easthampton Rd

    HOMES (RETIRED, NURSING) • 57,168 SF
    Value Estimation
    $795,000
    260 Easthampton Rd, Holyoke, MA 01040-1213
    View details
    98 Lower Westfield Rd

    98 Lower Westfield Rd

    Individual retail properties • 38,000 SF
    Value Estimation by Request
    98 Lower Westfield Rd, Holyoke, MA 01040
    View details
    293-299 Clemente St

    293-299 Clemente St

    Office Units
    Value Estimation by Request
    293-299 Clemente St, Holyoke, MA 01040
    View details
    293-299 Clemente St

    293-299 Clemente St

    Office Units
    Value Estimation by Request
    293-299 Clemente St, Holyoke, MA 01040
    View details
    254 Westfield Rd

    254 Westfield Rd

    Individual retail properties • 23,000 SF
    Value Estimation by Request
    254 Westfield Rd, Holyoke, MA 01040
    View details
    98 Lower Westfield Rd

    98 Lower Westfield Rd

    Medical Office Space • 38,000 SF
    Value Estimation by Request
    98 Lower Westfield Rd, Holyoke, MA 01040
    View details
    45 Lowr Westfield Rd

    45 Lowr Westfield Rd

    HOMES (RETIRED, NURSING) • 135,552 SF
    Value Estimation
    $2,305,000
    45 Lowr Westfield Rd, Holyoke, MA 01040-2747
    View details
    36 Lowr Westfield Rd

    36 Lowr Westfield Rd

    HOMES (RETIRED, NURSING) • 110,553 SF
    Value Estimation
    $1,005,000
    36 Lowr Westfield Rd, Holyoke, MA 01040-2749
    View details

    Holyoke, MA Healthcare Properties Investment Opportunities Market Analysis

    Explore 12 healthcare properties for sale in Holyoke, MA on our real estate platform. These investment opportunities span a total of 38,286 square feet of properties for sale, with an estimated market value of $2,290,000.

    Sale prices for medical real estate in Holyoke, MA start at $2,290,000, averaging $2,290,000, and reaching up to $2,290,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Senior Housing / Retirement Homes 1

    Demographics Overview

    Population 38K
    Population Growth (5Y) -6.0%
    Median Household Income $51,892
    College Educated 16.6%

    High-Yield Neighborhoods for Strategic Investment

    Identify Holyoke submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    01040 $2.3M

    Taxes & Financing

    Tax Rate (average for all types) 3.91%
    Property Tax per SF $32.04 per sq ft
    Tax Rate vs County Average 1.03 pp above county avg
    Average Loan-to-Value 65.0%

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