Minnehaha County, SD Commercial Real Estate for Sale

List

Map

Sioux Falls, SD Rapid City, SD Aberdeen, SD Huron, SD Lead, SD Watertown, SD Spearfish, SD Tea, SD

179 properties

Sort:

Updated: Apr 16

Historic Office Building

335 N Main Ave, Sioux Falls, SD 57104

$2,600,000

14,368 sqft 0.44 AC lot

14,368‑square‑foot office building constructed in 1892
Designed by architect Dow Wallace
Original oak, pine, maple, and cherry flooring on the main level
Fourteen‑foot ceilings on the main floor
Approximately 1,300 square feet of finished basement space with garden‑level windows

View details

This listing looks promising.

Here's a quick look at some key insights for

335 N Main Ave, Sioux Falls, SD 57104

View Property Analytics

Est. Cap Rate

7.4%
Above avg (5.9%)
Est. NOI

$192K
Annual
Price @ 7% Cap

$2.75M
Above asking
Property Type

Office Building
Built 1892

View Property Analytics

Updated: Nov 13, 2025

Masonry Gas Station Property

211 E 3rd St, Dell Rapids, SD 57022

$137,500

2,400 sqft 0.43 AC lot

2,400‑square‑foot masonry structure built in 1920
0.4303‑acre corner parcel at E 3rd St and Clark Ave
Lot dimensions measure 132 by 142 feet
B‑2 General Business zoning
Concrete flooring and available natural gas

View details

Mixed-Use Property with Hair Salon

524 N Main Ave, Garretson, SD 57030

$113,999

1,414 sqft 0.08 AC lot

Brick-veneer building pairs a leased salon with a remodeled apartment above.

View details

Drive-Through Storefront Property

1730 East 10th Street, Sioux Falls, SD 57103

$800,000

605 sqft

Vacant retail space with an existing drive-through, pylon sign, and access near I-229.

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Commercial Land Site for Retail or Office

1301 E Robur Dr, Sioux Falls, SD 57104

$1,500,000

2.65 AC lot

C-2 zoned commercial land totaling 2.6514 acres with daily traffic along Cliff Ave in Sioux Falls.

View details

Compact Warehouse with Garage Door

405 W 16TH St, Sioux Falls, SD 57104

$159,900

741 sqft 0.11 AC lot

Functional commercial space with concrete flooring, gas heat, electrical service, and paved access in a central Sioux Falls setting.

View details

Retail Showroom with Loading Docks

2715 E 10th St, Sioux Falls, SD 57103

$1,500,000

18,296 sqft 0.83 AC lot

A C-2 showroom on E 10th St features an open floor plan, large north-facing windows, and two loading docks.

View details

Sioux Falls Adaptable Commercial Building

4800 N 4th Ave, Sioux Falls, SD 57104

$2,250,379

49,424 sqft

49,424 SF vacant building suitable for daycare, medical, or office.

View details

Industrial Land Lot with Utilities

602 S Garfield Ave, Dell Rapids, SD 57022

$220,000

1.87 AC lot

Industrial lot in Fiegen Industrial Park with public water, public sewer, and electricity available for development.

View details

Development Land in Colton, SD

Glenn Ave, Colton, SD 57018

$250,000

4.79 AC lot

4.79 acres of land prime for development in Colton, SD.

View details

Sioux Falls Office For Sale

5604 W. 41st Street, Sioux Falls, SD 57106

$915,000

2,700 sqft

Office property with vacant suite and parking available for sale.

View details

Commercial Land with Highway 115 Frontage

600 E Quartzite St, Dell Rapids, SD 57022

$269,900

1.03 AC lot

General Business-zoned commercial lot with public water and public sewer plus road frontage and access to Highway 115.

View details

Office Suite with Reception and Six Offices

120 S Indiana Ave, Sioux Falls, SD 57104

Contact for pricing

0.14 AC lot

Office suite with a large reception area, six offices, and shared bathrooms, served by central heating and central air.

View details

High-Quality Building on Russell Street

621 West Russell Street, Sioux Falls, SD 57104

$2,230,000

20,141 sqft

Well-maintained building with newer roof and HVAC, great visibility.

View details

Three Adjacent Development Lots

2300 E 5th St, Sioux Falls, SD 57103

$275,000

4.24 AC lot

Three contiguous lots totaling 5.4184 acres are offered in a single transaction on E 5th Street.

View details

Self Storage Facility

1400 S Van Epps Ave, Sioux Falls, SD 57105

$3,500,000

1.18 AC lot

The facility features concrete and carpet flooring with central heating and air conditioning.

View details

Sioux Falls Data Center Opportunity

500 East 56th Street, Sioux Falls, SD 57104

$9,524,711

122,293 sqft

122,293 SF data center or office building for sale.

View details

Fenced Commercial Land

4th St, Dell Rapids, SD 57022

$79,900

0.32 AC lot

Commercial parcel with Central Business zoning and chain-link fencing in Dell Rapids.

View details

Drive-Thru Restaurant and Retail Buildings

3820 W. 41st Street, Sioux Falls, SD 57106

Contact for pricing

5,261 sqft 1.03 AC lot

Two leased retail buildings anchored by a drive-thru Arby’s plus a second street-level tenant on 1.03 acres.

View details

Industrial Land Parcel for Development

Ledge Rock Ave, Rowena, SD 57056

$435,600

2.00 AC lot

Two-acre industrial-zoned parcel offers flexible site options with convenient access to the Sioux Falls area.

View details

Retail Shop with Customer Office

3101 S. Shirley Avenue, Sioux Falls, SD 57106

Contact for pricing

4,161 sqft

Retail shop space features a customer office at the front, with ample parking and two curb cuts.

View details

Sioux Falls Specialty Property

705 E 60th St N, Sioux Falls, SD 57104

$6,067,138

124,103 sqft

Specialty property suitable for data center or industrial use.

View details

Multi-Suite Office Building

629 S Minnesota Ave, Sioux Falls, SD 57104

Contact for pricing

14,562 sqft 0.78 AC lot

Built in 1983, the property offers 12 office suites across three floors on two zoned parcels.

View details

Flex Space With Drive-Through Bays

47174 Haylie St, Sioux Falls, SD 57107

Contact for pricing

9,500 sqft

Three-unit commercial layout with service infrastructure, individual bathrooms, and additional land for outside storage.

View details

Minnehaha County, SD Commercial Real Estate Market Trends and Statistics

Explore 179 commercial real estate for sale in Minnehaha County, SD, showcased through 179 active listings on our real estate platform. These investment opportunities span a total of 9,125,767 square feet of properties for sale, with an estimated market value of $52,992,027.

Sale prices for business properties in Minnehaha County, SD start at $70,000, averaging $1,709,420, and reaching up to $9,524,711 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

List

Map