San Angelo, TX Commercial Real Estate for Lease

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Historic Office Suite
Updated: Aug 20
Historic Office Suite

421 W Concho Avenue, San Angelo, TX 76903

$3,995/Mo
2,501 sqft 0.27 AC lot
2,501 square feet of office space
Building constructed in 1927
421 W. Concho Avenue in downtown San Angelo
Multiple private offices plus conference and meeting areas
Hardwood floors, built‑in storage, kitchenette, and two restrooms
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Historic Two-Story Office Space
Updated: Jun 17
Historic Two-Story Office Space

332 Pulliam Street, San Angelo, TX 76903

$2,100/Mo
2,500 sqft
2,500 SF office space across two floors in the Gandy's building complex in San Angelo, TX
First floor includes 5 offices, reception area, open area, 1 conference/breakroom, and 2 bathrooms
Second floor includes 3 offices, 1 large open room, and 1 bathroom
Central heating and central air conditioning
Parking lot on‑site
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Move-In-Ready Medical Office
Move-In-Ready Medical Office

1820 Sunset Drive, San Angelo, TX 76904

$3,800/Mo
2,800 sqft

Move-in-ready medical office with ADA-compliant reception, exam rooms, private offices, and rear staff parking.

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Retail Space with Display Windows
Retail Space with Display Windows

130-113 E Concho Ave, San Angelo, TX 76903

$1,741/Mo
1,370 sqft

An open commercial suite includes a separate storage or office room and one restroom.

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Move-In Ready Office Suite
Move-In Ready Office Suite

1518 W Beauregard Avenue, San Angelo, TX 76901

$3,500/Mo
4,250 sqft

Remodeled office space with private offices, ADA restrooms, and a dedicated break area for immediate occupancy.

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Office Unit With Multiple Offices
Office Unit With Multiple Offices

112 N Pierce Street, San Angelo, TX 76901

$1,300/Mo
1,300 sqft 0.34 AC lot

Professional office layout with a reception area and on-site parking in downtown San Angelo.

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Mixed-Use Retail Property with Apartments
Mixed-Use Retail Property with Apartments

1225 S Chadbourne Street, San Angelo, TX 76903

$1,000/Mo
1,811 sqft 0.11 AC lot

Commercial building combining a retail area with two attached apartments and central HVAC.

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Medical Office Suite with Parking
Medical Office Suite with Parking

112 N Pierce St, San Angelo, TX 76901

$1,300/Mo
1,300 sqft

Office suite includes multiple offices, a reception area, and on-site parking, available September 15, 2025.

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Three-Space Office Property
Three-Space Office Property

716 Koenigheim Street, San Angelo, TX 76903

$500/Mo
1,200 sqft

Flexible leasing allows one or all three office spaces to be occupied.

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Yard-Backed Industrial Flex Property
Yard-Backed Industrial Flex Property

2901 W Fm 2105, San Angelo, TX 76903

$7,500/Mo
5,000 sqft

Fenced yard and newly built shop with offices, multiple bay doors, and high-clearance space for small to growing operations.

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Office Suite with Rear Entry
Office Suite with Rear Entry

1017 Caddo St, San Angelo, TX 76901

$1,400/Mo
1,000 sqft

Office suite offers two private offices, a reception/work area with sink, and rear covered parking access.

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Restaurant with Covered Outdoor Canopy
Restaurant with Covered Outdoor Canopy

34 E Ave D, San Angelo, TX 76903

Contact for pricing
9,614 sqft

Flexible layout includes multiple dining areas, a full-service bar, and commercial kitchen.

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Upstairs Office Unit with Conference Room
Upstairs Office Unit with Conference Room

210 S Chadbourne Street, San Angelo, TX 76903

$2,000/Mo
2,250 sqft 0.09 AC lot

Professional office setting with independent access, a private bathroom, meeting space, and on-site parking.

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Warehouse-Showroom with Mezzanine Offices
Warehouse-Showroom with Mezzanine Offices

914-918 Arroyo St, San Angelo, TX 76903

Contact for pricing
7,500 sqft 0.55 AC lot

Leasing space includes a front showroom, back warehouse with two overhead doors, and a second-floor office/mezzanine level.

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Updated Retail Suite
Updated Retail Suite

2312 W Avenue N, San Angelo, TX 76904

$1,500/Mo
1,100 sqft 0.14 AC lot

Corner positioning, refreshed finishes, and front windows support retail presentation and flexible interior planning.

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Warehouse with Multiple Bay Doors
Warehouse with Multiple Bay Doors

2421 Chadbourne Street, San Angelo, TX 76903

$4,500/Mo
6,378 sqft

Heated and cooled warehouse with front-office bathrooms, concrete flooring, and a fenced parking lot.

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Remodeled Private Office Suite
Remodeled Private Office Suite

100 W Twohig Ave, San Angelo, TX 76901

Contact for pricing
1,250 sqft

Professional workspace with reception, four private offices, a break area, and restroom near downtown.

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Fenced Flex Space
Fenced Flex Space

4152 Arden Road, San Angelo, TX 76901

$750/Mo
1,000 sqft

Office and warehouse areas are available in varying sizes for flexible commercial use.

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Endcap Retail Suite with Restrooms
Endcap Retail Suite with Restrooms

613-617 W 29th St, San Angelo, TX 76903

Contact for pricing
5,000 sqft

Second-generation endcap suite includes primarily open retail area, storage, and two restrooms with display windows.

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Sterile Compounding Pharmacy Space
Sterile Compounding Pharmacy Space

3123 Executive Drive, San Angelo, TX 76904

$3,620/Mo
1,810 sqft

Medical office suite built for sterile compounding, featuring HEPA filtration and a clean room.

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Enclosed Retail Mall Lease Space
Enclosed Retail Mall Lease Space

4001 Sunset Dr, San Angelo, TX 76904

Contact for pricing
500 sqft

Enclosed retail mall offers available space ranging from 500 to 15,000 square feet for lease.

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Workshop Flex Space
Workshop Flex Space

28 E Harris Avenue, San Angelo, TX 76903

$1,200/Mo
1,000 sqft

Functional contractor workspace with loading access, built-in storage, restroom, and secured fencing.

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Freestanding Restaurant with Equipped Kitchen
Freestanding Restaurant with Equipped Kitchen

3909 Sunset Dr, San Angelo, TX 76904

Contact for pricing
7,872 sqft 1.30 AC lot

Freestanding restaurant on an outparcel to Sunset Mall, with a main dining area, raised bar section, and kitchen FF&E included.

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Flex Space with Overhead Doors
Flex Space with Overhead Doors

4540 N Bentwood Drive, San Angelo, TX 76904

$11,500/Mo
7,500 sqft 1.34 AC lot

Versatile commercial building combining open operational space with private offices, restrooms, parking, and overhead access.

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San Angelo, TX Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in San Angelo, TX with 60 listings featured on our commercial real estate exchange. The current inventory includes 278,007 square feet of properties with an estimated lease value of $345.60.

Estimated lease rates for Commercial real estate in San Angelo, TX begin at $5 SF/Yr, with an average of $17.28 SF/Yr and extend to $96 SF/Yr.
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