San Angelo, TX Medical Office Space for Rent & Lease

Updated: Jun 1

Medical Office Space with Clean Room

3123 Executive Drive, San Angelo, TX 76904

$3,620/Mo

1,810 sqft 0.93 AC lot

1,810 SF medical office property
Clean room with HEPA filters
Office areas for sterile compounding pharmacy use
C/O Commercial Office zoning
0.93‑acre site with open parking lot

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Updated: Jul 2

Move-In-Ready Medical Office

1820 Sunset Drive, San Angelo, TX 76904

$3,000/Mo

2,800 sqft 1.10 AC lot

2,800‑square‑foot medical office on 1.1 acres
Three private offices and five exam rooms
Primary office includes a private bathroom and shower
Waiting area, reception, nurses’ station, storage, and three restrooms
Private rear parking area with parking lot and alley access

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Medical Office Suite with Parking

112 N Pierce St, San Angelo, TX 76901

$1,300/Mo

1,300 sqft

Office suite includes multiple offices, a reception area, and on-site parking, available September 15, 2025.

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Sterile Compounding Pharmacy Space

Na-3123 Executive Dr, San Angelo, TX 76904

$3,620/Mo

Suite includes HEPA filtration, a clean room, and office space for sterile compounding operations.

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Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 4 Active listings in San Angelo, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office with Exam Rooms

4009 Ridgemont Dr, Abilene, TX 79606

$4,500/Mo

2,772 sqft

A clinic-configured suite offers imaging space, reception workstations, and a designated parking lot.

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Medical Office Space

6452 Central Park Blvd, Abilene, TX 79606

Contact for pricing

5,596 sqft

Purpose-built medical office space supporting outpatient and professional healthcare services.

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Flexible Multi-Suite Commercial Space

8805 Fm 307, Midland, TX 79706

Contact for pricing

12,000 sqft

Multiple suites on FM 307 offer flexible leasing for retail, office, medical, service, or mixed-use tenants.

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Medical Office with Private Offices

102-2407 W Louisiana Ave, Midland, TX 79701

Contact for pricing

1,393 sqft

Move-in-ready office suite with five private offices, two restrooms, and recent interior remodel.

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Similar Spaces for Sale in San Angelo, TX

Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

ADA-Compliant Office Unit

2418 N Bryant Boulevard, San Angelo, TX 76903

$750,000

2,275 sqft 0.88 AC lot

Flexible office layout with direct access from both directions of North Bryant Boulevard.

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Medical Office Space with Private Rooms

3812 Arden Rd, San Angelo, TX 76901

$549,500

Configured with plumbing, reception, and breakroom areas for office, dental, medical, spa, or salon operations.

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Remodeled Medical Office Building

3111 Southwest Blvd, San Angelo, TX 76904

Contact for pricing

3,000 sqft

Turnkey medical office with remodeled interior, reception/waiting area, four exam rooms, and multiple treatment and office spaces.

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San Angelo, TX Medical Office Space Lease Rates & Market Statistics

Explore 4 Medical Office Space listings for lease in San Angelo, TX on Realmo, a commercial real estate exchange covering the San Angelo area. The current inventory totals 5,910 square feet of properties.

Asking lease rates for Medical Office Space in San Angelo start at $12 SF/Yr, average $16.29 SF/Yr, and reach $24 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $16.29 SF/Yr is 32% below the Texas state average of $24.11 SF/Yr.

San Angelo accounts for 100% of the 4 medical office space listings currently available across Tom Green County. Medical Office Space is one of the more limited space types in San Angelo, with just 4 listings currently available — a scarcity worth factoring into lease negotiations. Also worth a look for tenants weighing alternatives: Office Units (19 listings) elsewhere in the San Angelo market.