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    Lancaster, SC Commercial Real Estate for Lease

    7 results
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    Main Street Commercial Space Available
    $5,000 / Mo

    Main Street Commercial Space Available

    120 S Main St, Lancaster, SC 29720

    Versatile commercial space in downtown Lancaster with high visibility.

    • Prime location in downtown Lancaster
    • High visibility and foot traffic
    • Versatile layout for various commercial ventures
    • 100% air conditioned showroom warehouse space
    • Excellent signage opportunities
    View details
    Downtown Lancaster Office Space
    $15 SF/Yr
    3,360 SF

    Downtown Lancaster Office Space

    114 Gay St, Lancaster, SC 29720

    Prime Lancaster SC location, flexible spaces.

    • Two units available, 1,520‑1,840 square feet each, suitable for various uses including office, medical, and retail.
    • Units available for immediate occupancy; ideal for 2‑4 tenants.
    • High‑growth area: 12.7% population increase 2020‑2023, projected 25% increase over next 15 years, fueled by planned 2,500 new homes.
    • Proximity to 55+ communities provides a strong customer base.
    • Located 8 minutes from Lancaster Golf Club and 6 minutes from University of South Carolina Lancaster.
    Updated: Dec 11, 2024
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    Lancaster Retail Space - Hwy 200
    Contact for pricing
    2,322 SF

    Lancaster Retail Space - Hwy 200

    Prime Lancaster retail/office, 2322 SF.

    100 Monroe Hwy, Lancaster, SC 29720
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    University Place Retail Center
    Contact for pricing
    12,800 SF

    University Place Retail Center

    Lancaster, SC: 8,000 SF Available

    945-973 Highway 9 Byp, Lancaster, SC 29720
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    University Place Retail Opportunity
    Contact for pricing
    14,400 SF

    University Place Retail Opportunity

    Lancaster, SC: 6,000 SF Available

    905-933 Highway 9 Byp, Lancaster, SC 29720
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    1256 Highway 9 Byp
    Contact for pricing
    181,542 SF

    1256 Highway 9 Byp

    Retail properties & Spaces • 181,542 SF

    1256 Highway 9 Byp, Lancaster, SC 29720
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    South Square Retail Center - Lancaster, SC
    Contact for pricing
    44,350 SF

    South Square Retail Center - Lancaster, SC

    High-growth Lancaster, SC retail space.

    0 Airport Rd And Barton Rd, Lancaster, SC 29720
    View details
    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 7 Active listings in Lancaster, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 69 Properties for Sales.

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Charming Two-Story Office Building
    $25 SF/Yr
    2,638 SF

    Charming Two-Story Office Building

    Two-story office building near Waxhaw's Main Street intersection.

    501 N Providence St, Waxhaw, NC 28173
    View details
    Charming Commercial Space in Waxhaw
    $2,500 / Mo
    44,867 SF

    Charming Commercial Space in Waxhaw

    Flexible commercial space in Waxhaw with neighborhood center zoning.

    5309 Waxhaw Marvin Rd, Waxhaw, NC 28173
    View details
    Carolina Commons Retail Space
    Contact for pricing
    76,796 SF

    Carolina Commons Retail Space

    High-traffic retail space available now.

    6285 Carolina Cmns Dr, Indian Land, SC 29707
    View details
    Retail Space in Growing Corridor
    Contact for pricing

    Retail Space in Growing Corridor

    Retail space available 1/1/2026 in a high-growth area.

    7710 Charlotte Hwy, Indian Land, SC 29707
    View details

    Explore Similar Spaces for Sale in Lancaster, SC

    Consider Similar Space for Sale. We found 69 Spaces in Nearby Locations matching your search parameters.

    Versatile Land on Charlotte Highway
    $1,500,000
    5.61 Acres

    Versatile Land on Charlotte Highway

    5.61-acre wooded property with residential and commercial potential.

    Charlotte Hwy, Lancaster, SC 29707
    View details
    Prime Land on Highway 521
    $2,500,000
    3.96 Acres

    Prime Land on Highway 521

    3.96 acres ideal for commercial or residential development.

    6993 Charlotte Hwy, Lancaster, SC 29707
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    Prime Development Land on Charlotte Highway
    $2,200,000
    15.55 Acres

    Prime Development Land on Charlotte Highway

    Development opportunity on a high-traffic corridor near residential developments.

    2383 Charlotte Hwy, Lancaster, SC 29720
    View details
    Two Professional Buildings Near MUSC
    $975,000
    0.82 Acres

    Two Professional Buildings Near MUSC

    Two professional office buildings near MUSC in Lancaster, South Carolina.

    1201 Colonial Cmns Ct, Lancaster, SC 29720
    View details
    Commercial Lot on Highway S 200
    $69,900
    0.50 Acres

    Commercial Lot on Highway S 200

    Prime commercial lot with high visibility and utilities access.

    2067 Great Falls Hwy, Lancaster, SC 29720
    View details
    19.32 Acres in Indian Land
    $625,000
    19.32 Acres

    19.32 Acres in Indian Land

    Land with natural features ideal for country living.

    6327 Witherspoon Trl, Lancaster, SC 29720
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    Prime Commercial Land on Charlotte Highway
    $2,200,000
    15.55 Acres

    Prime Commercial Land on Charlotte Highway

    15.55 acres with high traffic and development potential.

    2383 Charlotte Hwy, Lancaster, SC 29720
    View details
    Commercial Lot on Highway S 200
    $69,000
    0.50 Acres

    Commercial Lot on Highway S 200

    Prime commercial lot with high visibility and utilities connected.

    2067 Great Falls Hwy, Lancaster, SC 29720
    View details
    Secluded Land with Creek Border
    $650,000
    77.99 Acres

    Secluded Land with Creek Border

    77+ acre lot perfect for recreation and residential use.

    Daystar Rd, Lancaster, SC 29720
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    38 Acres in Lancaster, SC
    $2,100,000
    38.00 Acres

    38 Acres in Lancaster, SC

    38-acre property suitable for redevelopment, subdivision, or private residence.

    9504 Van Wyck Rd, Lancaster, SC 29720
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    Commercial Land in Lancaster, SC
    $75,000
    0.28 Acres

    Commercial Land in Lancaster, SC

    Prime commercial land with high visibility and easy access.

    E Arch St, Lancaster, SC 29720
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    Lancaster County Acreage with Development Potential
    $2,775,000
    84.67 Acres

    Lancaster County Acreage with Development Potential

    84.67 acres in Lancaster County ideal for various uses.

    1049 Culp Ferguson Rd, Lancaster, SC 29720
    View details
    Commercial Land on Corner Lot
    $272,500
    1.81 Acres

    Commercial Land on Corner Lot

    Corner lot commercial land with road frontage and utilities.

    S Main St, Lancaster, SC 29720
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    Lancaster, SC Turnkey Acreage
    $997,000
    196.93 Acres

    Lancaster, SC Turnkey Acreage

    196+/- acres in Lancaster, SC, ideal for recreation or homestead.

    Green Rd, Lancaster, SC 29720
    View details
    Lancaster Land with Highway Frontage
    $1,600,000
    25.00 Acres

    Lancaster Land with Highway Frontage

    25 acres of land ideal for development or investment.

    3080 Charlotte Hwy, Lancaster, SC 29720
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    Undeveloped Land Parcel in Lancaster
    $375,000
    7.00 Acres

    Undeveloped Land Parcel in Lancaster

    7-acre flat land parcel suitable for various uses.

    2233 Riverside Rd, Lancaster, SC 29720
    View details
    Lancaster Farmland with Barn
    $799,900
    39.80 Acres

    Lancaster Farmland with Barn

    39.8 acres of rolling farmland with barn and ponds.

    992 S Potter Rd, Lancaster, SC 29720
    View details

    Lancaster, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Lancaster, SC with 76 listings featured on our commercial real estate exchange. The current inventory includes 146,361,600 square feet of properties with an estimated lease value of $15 SF/Yr.

    Estimated lease rates for Commercial real estate in Lancaster, SC begin at $15 SF/Yr, with an average of $15 SF/Yr and extend to $15 SF/Yr.
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