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    Clemson, SC Commercial Real Estate for Lease

    10 results
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    Downtown Clemson Retail Space Available
    $2,800 / Mo

    Downtown Clemson Retail Space Available

    382 College Ave Unit, Clemson, SC 29631

    Retail space in downtown Clemson, formerly a coffee shop.

    • Prime downtown Clemson location.
    • Approximately 2100 sqf. of finished space.
    • Accessible from Kieth St.
    • Central heating and cooling.
    • Durable brick construction.
    Updated: Dec 30, 2025
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    Townhome Near Clemson Campus
    $1,200 / Mo

    Townhome Near Clemson Campus

    343 Old Greenville Hwy, Clemson, SC 29631

    Townhome near Clemson, private bedrooms, CATbus route, available August 2025.

    • Very close proximity to Clemson University campus.
    • Located on the CATbus route.
    • Private bedrooms, each with its own bathroom.
    • Rear bedroom with a large private walk‑out balcony.
    • Easy bike ride to Clemson.
    Updated: Aug 26, 2025
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    Prime Retail Space, Pickens County
    Contact for pricing
    76,566 SF

    Prime Retail Space, Pickens County

    High-traffic location, multiple units available

    500 Old Greenville Hwy, Clemson, SC 29631
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    Clemson Retail Space - Tiger Blvd
    $22 SF/Yr
    1,300 SF

    Clemson Retail Space - Tiger Blvd

    1300 SF Restaurant Space Available Now!

    1067 Tiger Blvd, Clemson, SC 29631
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    Clemson Retail Space: 15,214 SF Available
    Contact for pricing
    44,128 SF

    Clemson Retail Space: 15,214 SF Available

    High-traffic Clemson retail space, ideal for multiple tenants.

    107 Canoy Ln, Clemson, SC 29631
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    Freestanding Restaurant Space Available
    $40 SF/Yr
    4,029 SF

    Freestanding Restaurant Space Available

    4,029 SF freestanding restaurant with drive-thru in Clemson, SC.

    1071 Tiger Blvd, Clemson, SC 29631
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    Retail Space Near Clemson University
    Contact for pricing
    1,233 SF

    Retail Space Near Clemson University

    Publix-anchored retail space with high visibility near Clemson University.

    1390 Tiger Blvd, Clemson, SC 29631
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    Retail/Restaurant Space Near Clemson University
    Contact for pricing
    3,500 SF

    Retail/Restaurant Space Near Clemson University

    Retail/restaurant space with dedicated parking and lake access.

    894 Tiger Blvd, Clemson, SC 29631
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    Retail/Restaurant Space Near Clemson University
    Contact for pricing
    1,401 SF

    Retail/Restaurant Space Near Clemson University

    Retail/restaurant spaces available in mixed-use student housing project.

    114 Earle St, Clemson, SC 29631
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    Mixed-Use Property Near Clemson Campus
    Contact for pricing

    Mixed-Use Property Near Clemson Campus

    Mixed-use property with residential and retail components near Clemson University.

    111 Earle St, Clemson, SC 29631
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    Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 10 Active listings in Clemson, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

    Explore Commercial Real Estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Hartwell Village Development Opportunity
    Contact for pricing

    Hartwell Village Development Opportunity

    New development opportunity with excellent visibility and easy access.

    13046 Clemson Blvd, Seneca, SC 29678
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    Retail Space Near Clemson University
    $21 SF/Yr
    43,000 SF

    Retail Space Near Clemson University

    End-cap retail space with drive-thru potential near Clemson University.

    1085 Old Clemson Hwy, Seneca, SC 29672
    View details
    Historic Building in Pendleton Square
    $3,100 / Mo

    Historic Building in Pendleton Square

    Iconic building in vibrant Pendleton, SC, near Clemson University.

    102 Exchange St, Pendleton, SC 29670
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    Land Available For Lease
    Contact for pricing

    Land Available For Lease

    Land available for lease in Pendleton, South Carolina.

    7624 Highway 76, Pendleton, SC 29670
    View details

    Explore Similar Spaces for Sale in Clemson, SC

    Consider Similar Space for Sale. We found 5 Spaces in Nearby Locations matching your search parameters.

    Commercial Building on Highway 123
    $1,349,990
    0.48 Acres

    Commercial Building on Highway 123

    Commercial building in Clemson with ample parking and high traffic.

    990 Tiger Blvd, Clemson, SC 29631
    View details
    Clemson Development Opportunity
    $1,299,774
    7.66 Acres

    Clemson Development Opportunity

    7+ acres zoned for hotel or multifamily development near Clemson.

    76 Hwy W, Clemson, SC 29631
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    Commercial Space in Downtown Clemson
    Pending
    $699,000

    Commercial Space in Downtown Clemson

    Rare opportunity to purchase commercial space in downtown Clemson.

    105 Sloan St, Clemson, SC 29631
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    Gorgeous Townhome in Patrick Square
    $432,500
    1,620 SF

    Gorgeous Townhome in Patrick Square

    Practically new 2-bedroom, 2.5-bath townhome with modern features and amenities.

    174 Thomas Green Blvd, Clemson, SC 29631
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    Clemson Commercial Land - 7.66 Acres
    $1,299,774
    7.66 Acres

    Clemson Commercial Land - 7.66 Acres

    Prime Clemson location, ideal for hotel or multi-family development.

    00 Hwy 76 Hwy, Clemson, SC 29631
    View details

    Clemson, SC Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Clemson, SC with 15 listings featured on our commercial real estate exchange. The current inventory includes 232,131,240 square feet of properties with an estimated lease value of $62 SF/Yr.

    Estimated lease rates for Commercial Real Estate in Clemson, SC begin at $22 SF/Yr, with an average of $31 SF/Yr and extend to $40 SF/Yr.

    In Clemson, SC, current lease rates show:

    • Restaurants positioned at $31
    • Retail properties measuring $31
    • Drive through restaurants assessed at $40
    • Other restaurants calculated at $22
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    Browse Commercial real estate for Lease Near Clemson, SC

    Popular Searches in Clemson, SC

    Most Searched ZIP Codes in Clemson, SC

    • 29631

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