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Desoto County, MS Commercial Real Estate for Lease

104 results
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Southaven Commercial Space For Lease
$2,200 / Mo
2,905 SF

Southaven Commercial Space For Lease

9127 Corporate Dr, Southaven, MS 38671

Office and warehouse space available for lease in Southaven.

  • Two warehouses: 600 sq ft (with storage room) and 1240 sq ft (separate entry)
  • Includes front lobby, 3 offices, common area, and 2 bathrooms
  • Zoned C4
  • Parking available in front of the building
  • Heating: Natural Gas, Central
Updated: Oct 11, 2025
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New Commercial Space in Olive Branch
$2,000 / Mo
7,344 SF

New Commercial Space in Olive Branch

7550 Alexander Rd Lot Bay, Olive Branch, MS 38654

Modern commercial space ideal for retail, office, or service businesses.

  • Brand‑new 1,200 sq. ft. commercial space in a growing area of Olive Branch.
  • Versatile unit suitable for retail, office, or service‑based businesses.
  • Open layout ready for customization.
  • Ample parking and excellent visibility.
  • Affordable rent of $2,000 per month (or $2,200 for Goodman Road facing bay).
Updated: Dec 3, 2025
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New Retail Space in Horn Lake
$2,500 / Mo
1,271 SF

New Retail Space in Horn Lake

New retail/commercial space with high visibility and traffic.

6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
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New Retail Space in Horn Lake
$2,500 / Mo
1,271 SF

New Retail Space in Horn Lake

New retail/commercial space with high visibility and traffic.

6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
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New Retail Space in Horn Lake
$2,500 / Mo
1,255 SF

New Retail Space in Horn Lake

New retail/commercial space with high visibility and traffic.

6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
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New Commercial Space in Olive Branch
$2,200 / Mo
7,344 SF

New Commercial Space in Olive Branch

Modern commercial space ideal for retail, office, or service businesses.

7550 Alexander Rd Lot Bay, Olive Branch, MS 38654
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New Commercial Space in Olive Branch
$2,000 / Mo
7,344 SF

New Commercial Space in Olive Branch

Modern commercial space ideal for retail, office, or service businesses.

7550 Alexander Rd, Olive Branch, MS 38654
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Olive Branch Commercial Space Available
$3,150 / Mo
1,260 SF

Olive Branch Commercial Space Available

1,260 SF commercial space in high-traffic Olive Branch location.

10680 Goodman Rd, Olive Branch, MS 38654
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New Retail Space in Horn Lake
$2,500 / Mo
1,271 SF

New Retail Space in Horn Lake

New retail/commercial space with high visibility, built in 2025.

6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
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New Retail Space in Horn Lake
$2,500 / Mo
1,271 SF

New Retail Space in Horn Lake

New retail/commercial space with high visibility and traffic.

6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
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Hernando Commercial Space For Lease
$18 SF/Yr
1,800 SF

Hernando Commercial Space For Lease

1,800 SF commercial bay on Hwy 51, Hernando, MS.

341 Wheeler Rd, Hernando, MS 38632
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New Retail Space in Horn Lake
$2,500 / Mo
1,271 SF

New Retail Space in Horn Lake

New retail/commercial space in high-visibility location, built in 2025.

6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
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New Retail Space in Horn Lake
$2,500 / Mo
1,271 SF

New Retail Space in Horn Lake

New retail/commercial space with high visibility, built in 2025.

6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
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New Retail Space in Horn Lake
$2,500 / Mo
1,271 SF

New Retail Space in Horn Lake

New retail/commercial space with high visibility and traffic.

6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
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Prime Olive Branch Office Space
$38 SF/Yr
5,129 SF

Prime Olive Branch Office Space

Class A Office Suites Available Now

6812 Crumpler Blvd, Olive Branch, MS 38654
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Southaven Retail Space Available
Contact for pricing
324,801 SF

Southaven Retail Space Available

Tanger Outlets: Prime Retail Opportunity

5205 Airways Blvd, Southaven, MS 38671
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DeSoto County Warehouse - 60,000 SF
Contact for pricing
60,000 SF

DeSoto County Warehouse - 60,000 SF

Spacious warehouse, ideal for lease. Prime DeSoto location.

8735 Nail Rd, Olive Branch, MS 38654
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Horn Lake Drive-Thru Retail Space
$10 SF/Yr
10,810 SF

Horn Lake Drive-Thru Retail Space

10,810 SF Retail Building - High Visibility

6396 Us-51, Horn Lake, MS 38637
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Southaven Towne Center Retail Space
Contact for pricing
567,640 SF

Southaven Towne Center Retail Space

Prime MS Retail Center, 567K SF

6474 Towne Center Loop, Southaven, MS 38671
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Olive Branch Retail Center
Contact for pricing
18,827 SF

Olive Branch Retail Center

High-traffic retail space in Olive Branch, MS

5036 Goodman Rd, Olive Branch, MS 38654
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Olive Branch Retail Opportunity
$13 SF/Yr
13,225 SF

Olive Branch Retail Opportunity

Prime 13,225 SF Retail Building

7363 Goodman Rd, Olive Branch, MS 38654
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Hernando Retail Center: Prime Location
Contact for pricing
70,957 SF

Hernando Retail Center: Prime Location

70,957 SF Shopping Center, 1,998 SF Available

2631 Mcingvale Rd, Hernando, MS 38632
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Metro Commons Retail Space
Contact for pricing
15,000 SF

Metro Commons Retail Space

Olive Branch, MS Strip Center Opportunity

9150 Hacks Cross Rd, Olive Branch, MS 38654
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Desoto Plaza: Medical Office Space
$7 SF/Yr
18,400 SF

Desoto Plaza: Medical Office Space

Main Street Southaven Medical Offices

1219 Main St, Southaven, MS 38671
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Desoto County, MS Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in Desoto County, MS with 133 listings featured on our commercial real estate exchange. The current inventory includes 10,772,388,000 square feet of properties with an estimated lease value of $679 /Mo.

Estimated lease rates for Commercial Real Estate in Desoto County, MS begin at $3 SF/Yr, with an average of $16 SF/Yr and extend to $38 SF/Yr.

In Desoto County, MS, current lease rates show:

  • Retail properties positioned at $15
  • Individual retail properties measuring $16
  • Retail space assessed at $16
  • Office Properties & Spaces calculated at $17
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