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    Desoto County, MS Commercial Real Estate for Lease

    98 results
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    Retail/Office Space For Lease
    $1,000 / Mo
    900 SF

    Retail/Office Space For Lease

    7122 Highway 301 N, Horn Lake, MS 38637

    Multi-tenant retail/office space available in Horn Lake, MS.

    • High‑visibility location at the NE corner of MS Highway 302 and MS Hwy 301, with significant traffic flow.
    • Move‑in ready 900sf +/- space with updated paint, LVP floors, and new HVAC, furnace, and roof.
    • Plumbing already in place for salon wash basins and sink, suitable for salon or similar business.
    • Ample front door parking and covered walkway for convenient customer access.
    • Part of Lily Plaza Commercial Center with a diverse mix of retail, restaurant, and convenience store tenants.
    Updated: Mar 3
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    New Commercial Space in Olive Branch
    $2,000 / Mo
    7,344 SF

    New Commercial Space in Olive Branch

    7550 Alexander Rd, Olive Branch, MS 38654

    Modern commercial space ideal for retail, office, or service businesses.

    • Brand‑new 1,200 sq. ft. commercial space.
    • Located in a growing area of Olive Branch.
    • Versatile unit ideal for retail, office, or service‑based businesses.
    • Open layout ready for customization.
    • Ample parking and excellent visibility.
    Updated: Dec 3, 2025
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    New Commercial Space in Olive Branch
    $2,200 / Mo
    7,344 SF

    New Commercial Space in Olive Branch

    Modern commercial space ideal for retail, office, or service businesses.

    7550 Alexander Rd Lot Bay, Olive Branch, MS 38654
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    New Commercial Space in Olive Branch
    $2,000 / Mo
    7,344 SF

    New Commercial Space in Olive Branch

    Modern commercial space ideal for retail, office, or service businesses.

    7550 Alexander Rd Lot Bay, Olive Branch, MS 38654
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    Hernando Commercial Space For Lease
    $18 SF/Yr
    1,800 SF

    Hernando Commercial Space For Lease

    1,800 SF commercial bay on Hwy 51, Hernando, MS.

    341 Wheeler Rd, Hernando, MS 38632
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    Olive Branch Commercial Space Available
    $3,150 / Mo
    1,260 SF

    Olive Branch Commercial Space Available

    1,260 SF commercial space in high-traffic Olive Branch location.

    10680 Goodman Rd, Olive Branch, MS 38654
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    New Retail Space in Horn Lake
    $2,500 / Mo
    1,271 SF

    New Retail Space in Horn Lake

    New retail/commercial space with high visibility and traffic.

    6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
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    New Retail Space in Horn Lake
    $2,500 / Mo
    1,271 SF

    New Retail Space in Horn Lake

    New retail/commercial space with high visibility, built in 2025.

    6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
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    New Retail Space in Horn Lake
    $2,500 / Mo
    1,255 SF

    New Retail Space in Horn Lake

    New retail/commercial space with high visibility and traffic.

    6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
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    New Retail Space in Horn Lake
    $2,500 / Mo
    1,271 SF

    New Retail Space in Horn Lake

    New retail/commercial space in high-visibility location, built in 2025.

    6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
    View details
    New Retail Space in Horn Lake
    $2,500 / Mo
    1,271 SF

    New Retail Space in Horn Lake

    New retail/commercial space with high visibility and traffic.

    6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
    View details
    New Retail Space in Horn Lake
    $2,500 / Mo
    1,271 SF

    New Retail Space in Horn Lake

    New retail/commercial space with high visibility, built in 2025.

    6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
    View details
    New Retail Space in Horn Lake
    $2,500 / Mo
    1,271 SF

    New Retail Space in Horn Lake

    New retail/commercial space with high visibility and traffic.

    6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
    View details
    New Retail Space in Horn Lake
    $2,500 / Mo
    1,271 SF

    New Retail Space in Horn Lake

    New retail/commercial space with high visibility and traffic.

    6100 Horn Lk Rd Lot Bay, Horn Lake, MS 38637
    View details
    Medical Office Park Near I-55
    $19 SF/Yr
    1,206 SF

    Medical Office Park Near I-55

    Medical office space for lease near Baptist DeSoto Hospital.

    7900 Airways Blvd, Southaven, MS 38671
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    Olive Branch Warehouse Space Available
    Contact for pricing
    60,000 SF

    Olive Branch Warehouse Space Available

    60,000 SF warehouse space with office in Olive Branch.

    8735 Nail Rd, Olive Branch, MS 38654
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    Southaven Office Space For Lease
    $12 SF/Yr
    3,811 SF

    Southaven Office Space For Lease

    Office space available in Southaven, Mississippi, featuring small offices.

    7145 Swinnea Rd, Southaven, MS 38671
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    Hernando Office Space For Rent
    $21 SF/Yr
    1,050 SF

    Hernando Office Space For Rent

    Office space available in Hernando, Mississippi, approximately 1,050 square feet.

    2575 Caffey St, Hernando, MS 38632
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    Hernando Medical Office Space
    $20 SF/Yr
    4,608 SF

    Hernando Medical Office Space

    Medical office space in the heart of Hernando.

    124 W Commerce St, Hernando, MS 38632
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    Office Space on Goodman Road
    $28 SF/Yr
    1,500 SF

    Office Space on Goodman Road

    Office space for rent in a high-traffic location.

    892 Goodman Rd E, Southaven, MS 38671
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    Southaven Office and Retail Space
    $22 SF/Yr
    1,056 SF

    Southaven Office and Retail Space

    Office and retail space in the heart of Southaven.

    232 Goodman Rd, Southaven, MS 38671
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    Modern Office Space Available
    $11 SF/Yr
    2,524 SF

    Modern Office Space Available

    Efficient office spaces with utilities included and ample parking.

    2018 Mcingvale Rd, Hernando, MS 38632
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    Retail Space on Goodman Road
    $15 SF/Yr
    1,200 SF

    Retail Space on Goodman Road

    Retail space available in Horn Lake, Mississippi, built in 1996.

    3042-3058 Goodman Rd, Horn Lake, MS 38637
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    Retail Space in Prime Location
    $10 SF/Yr
    9,862 SF

    Retail Space in Prime Location

    9,862 SF retail space in Southaven, MS corridor.

    7065 Airways Blvd, Southaven, MS 38671
    View details

    Desoto County, MS Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Desoto County, MS with 233 listings featured on our commercial real estate exchange. The current inventory includes 8,736,829,200 square feet of properties with an estimated lease value of $654 /Mo.

    Estimated lease rates for Commercial real estate in Desoto County, MS begin at $3 SF/Yr, with an average of $17 SF/Yr and extend to $38 SF/Yr.
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