Saco, ME Commercial Real Estate for Lease

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Biddeford, ME Scarborough, ME South Portland, ME Westbrook, ME Portland, ME Wells, ME Waterboro, ME Gorham, ME
Downtown Saco Office Space Available
Updated: Nov 24, 2025
Downtown Saco Office Space Available

209 Main St, Saco, ME 04072

$18 SF/Yr
Prime downtown Saco location
On‑site parking available
1,222± SF of 3rd floor office/studio space
Steps away from the Amtrak Downeaster
Easy access to I‑95
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Saco Flex Space Available
Updated: Jun 19, 2021
Saco Flex Space Available

42 Industrial Park Rd, Saco, ME 04072

Contact for pricing
4,590 sqft
Flexible space: 3,000 - 4,590± SF suitable for office/medical office uses.
Ample free parking.
Great location: easily accessible, less than three minutes to the Maine Turnpike.
Overhead door.
Skylight.
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Versatile Commercial/Industrial Space For Sale
Versatile Commercial/Industrial Space For Sale

644 Main Street, Saco, ME 04072

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5,250 sqft 0.75 AC lot

Commercial/industrial building with retail and warehouse space available for sale.

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Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 3 Active listings in Saco, ME, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 11 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Fully ADA Compliant Office Space
Fully ADA Compliant Office Space

443 Main St, Biddeford, ME 04005

$3,200/Mo
1,610 sqft

Fully ADA compliant office space with on-site parking in a building located off Main Street.

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Scarborough Industrial Park Opportunity
Scarborough Industrial Park Opportunity

16 Washington Ave, Scarborough, ME 04074

$11 SF/Yr

Industrial property in Scarborough's premier park with highway access.

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Retail Outparcel For Lease
Retail Outparcel For Lease

299 Elm St, Biddeford, ME 04005

Contact for pricing

Retail outparcel available for lease.

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Retail Space on US Route 1
Retail Space on US Route 1

707 US Route 1, Scarborough, ME

Contact for pricing
10,000 sqft 3.13 AC lot

Retail suites available for rent on US Route 1.

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Similar Spaces for Sale in Saco, ME

Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

Freestanding Restaurant Building
Freestanding Restaurant Building

512 Main Street, Saco, ME 04072

$1,595,000
6,912 sqft 0.32 AC lot

Restaurant real estate and equipment are offered separately from the operating business, with an existing tenant in place.

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School Building with Classroom Kitchens
School Building with Classroom Kitchens

5 Willey Road, Saco, ME 04072

$2,900,000
10,260 sqft 5.29 AC lot

Educational facility with classroom kitchens, bathrooms, adaptable interior space, and public water and sewer service.

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Mixed-Use Property with Retail
Mixed-Use Property with Retail

239 Main Street, Saco, ME 04072

$649,000
4,976 sqft 0.09 AC lot

Two ground-floor retail units and upper-level offices support owner occupancy alongside rental income.

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Historic Brick NNN Property
Historic Brick NNN Property

190 Main Street, Saco, ME 04072

$995,000
8,736 sqft 0.05 AC lot

Fully leased downtown asset with central air, off-street parking, and a low-management lease structure.

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School Building in Industrial Zone
School Building in Industrial Zone

5 Willey Rd, Saco, ME 04072

$2,900,000
10,260 sqft

Existing site plan approval supports a building developed for school use within an industrial zoning district.

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Former School Building
Former School Building

50 Beach St, Saco, ME 04072

$1,925,000
15,228 sqft

Former educational improvements occupy the property in Saco.

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Historic Downtown NNN Building
Historic Downtown NNN Building

190 Main Street, Saco, ME 04072

$995,000
8,736 sqft

Fully leased NNN brick building with public transit access and downtown commercial convenience.

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Stand-Alone Restaurant Building
Stand-Alone Restaurant Building

512 Main Street, Saco, ME 04072

$1,595,000
6,912 sqft

Stand-alone restaurant building with ample parking and included real estate and equipment, sold without the operating business.

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Former School Building
Former School Building

50-56 Beach Street, Saco, ME 04072

Contact for pricing
15,228 sqft 0.91 AC lot

Flexible floor plan supports office, educational, daycare, and institutional uses.

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Refrigerated Distribution Facility
Refrigerated Distribution Facility

11 Lund Road, Saco, ME 04072

Contact for pricing
42,704 sqft 6.73 AC lot

Refrigerated warehouse with nine loading docks and freezer infrastructure on 6.73 acres in Saco’s industrial district.

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Retail
Retail

507 Main Street, Saco, ME 04072

Contact for pricing
5,363 sqft 1.66 AC lot

Shopping centers · 5,363 SF

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Saco, ME Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Saco, ME with 3 listings featured on our commercial real estate exchange. The current inventory includes 9,840 square feet of properties with an estimated lease value of $18.

Estimated lease rates for Commercial real estate in Saco, ME average $18 SF/Yr.
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