San Ysidro, CA Commercial Real Estate for Lease

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Office Space with Open Cube Layout
Office Space with Open Cube Layout

15333 Ave of Science, San Diego, CA 92128

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8,441 sqft

Office suite for lease with 11-foot ceilings, double-door glass entrance, and private offices plus meeting rooms.

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Class A Office Building
Class A Office Building

9444 Balboa Ave, San Diego, CA 92123

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5,956 sqft

Class A office space offered through 11/30/2026 with onsite fitness and a new amenity center.

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Class A Garden Office Building
Class A Garden Office Building

7777 Fay Ave, La Jolla, CA 92037

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2,896 sqft

Four-story Class A garden office building offering strong on-site building signage opportunities.

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Sublease Office Building
Sublease Office Building

3579 Valley Centre Dr, San Diego, CA 92130

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3,500 sqft

Office building available for sublease, offering 3,500 SF of workspace at 3579 Valley Centre Dr.

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Upstairs Office Suite with Reception
Upstairs Office Suite with Reception

3954 Murphy Canyon Rd, San Diego, CA 92123

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2,182 sqft

Second-floor suite includes reception, six private offices, open area, two restrooms, and storage.

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Class A Medical Office Suite
Class A Medical Office Suite

8008 Frost St, San Diego, CA 92123

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1,612 sqft

Class A medical office suites within a multi-building healthcare campus with parking and on-site management.

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Office Space for Lease
Office Space for Lease

4755 Eastgate Mall, San Diego, CA

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31,706 sqft 2.82 AC lot

Office space available for lease in San Diego, CA.

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Class A Flex Space with Two-Story Lobbies
Class A Flex Space with Two-Story Lobbies

10431 Wateridge Cir, San Diego, CA 92121

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15,177 sqft

Flex office and production space with nine private offices, multiple conference rooms, and a campus parking ratio of 3 per 1,000 RSF.

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Office Building with Panoramic Bay Views
Office Building with Panoramic Bay Views

550 W C St, San Diego, CA 92101

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15,688 sqft

Office building with an enhanced lobby, gym, and fully equipped conference room, plus EV charging and 24/7 security.

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Fitness Center with Outdoor Workout Deck
Fitness Center with Outdoor Workout Deck

1011 Union St, San Diego, CA 92101

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41,589 sqft

For rent with 4 contiguous floors, multiple elevators, and indoor/outdoor dining plus an outdoor workout deck.

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Office Building with Renovated Amenities
Office Building with Renovated Amenities

4180 La Jolla Village Dr, La Jolla, CA 92037

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3,156 sqft

Recently renovated office common areas, lobbies, restrooms, and gym with convenient parking and elevator access.

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Retail Space on Signalized Corner
Retail Space on Signalized Corner

644 E San Ysidro Blvd, San Ysidro, CA 92173

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3,021 sqft

Retail space offering prominent corner visibility with monument signage and a generous 6/1,000 SF parking ratio.

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Flex Warehouse with Office
Flex Warehouse with Office

9340 Cabot Dr, San Diego, CA 92126

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7,727 sqft

Flex warehouse suite with dock-high loading and an office portion, available for lease starting April 1, 2025.

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Point Loma Office/Retail Space
Point Loma Office/Retail Space

2810 Canon St, San Diego, CA

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1,200 sqft 0.41 AC lot

Renovated office/retail space in the heart of Point Loma.

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Sorrento Mesa Lab and Office
Sorrento Mesa Lab and Office

10431 Wateridge Cir, San Diego, CA

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34,002 sqft 9.47 AC lot

Class A lab and office space in Sorrento Mesa.

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Prime Commercial Property in San Diego
Prime Commercial Property in San Diego

San Diego, CA 92119

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Exceptional commercial property with modern amenities and versatile floor plans.

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Fitness Center with Ground Retail
Fitness Center with Ground Retail

1011 Union St, San Diego, CA 92101

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41,652 sqft

Fitness club space featuring 4 contiguous floors, direct parking access, and indoor/outdoor dining and lounge areas.

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Single-Story Office Building
Single-Story Office Building

12220 World Trade Dr, San Diego, CA 92128

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4,889 sqft

Former headquarters facility with mezzanine space at a business park entrance near Interstate 15.

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Office Spec Suite with Glass Entry
Office Spec Suite with Glass Entry

6256 Greenwich Dr, San Diego, CA 92122

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7,923 sqft

Recently completed office spec suite features a prominent glass double-door entry plus private offices and an open work area.

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Commercial Office Space Available
Commercial Office Space Available

401 B Street, San Diego, CA 92101

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Office space for rent in San Diego, CA.

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Multiple Office Solutions at CA, Spaces Little Italy. Contact us today to book a tour!
Multiple Office Solutions at CA, Spaces Little Italy. Contact us today to book a tour!

1420 200 & 300, Unit 100, San Diego, CA 92101

15 available spaces from 11 to 1,999 sqft
$129-$13,786/Mo per office

Find fully flexible work and meeting space in CA, Spaces Little Italy. Book a tour & get info

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North Park Office Space Available
North Park Office Space Available

3823 Ray St, San Diego, CA

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1,270 sqft 0.12 AC lot

Flexible office spaces in a sought-after San Diego commercial district.

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Flex Lab and Office Space
Flex Lab and Office Space

10431 Wateridge Cir, San Diego, CA 92121

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34,002 sqft

Class A lab and office flex space with dedicated lab rooms, 97 workstations, and structured surface parking.

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Retail Space with Excellent Visibility
Retail Space with Excellent Visibility

5261-5401 Linda Vista Road, San Diego, CA 92110

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Retail space near USD with high traffic and visibility.

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