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    Hillsboro, MO Retail Properties & Spaces for Sale

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    Saint Louis, MO Kansas City, MO Louis, MO
    Hillsboro Mixed-Use Redevelopment Opportunity
    $450,000
    6,090 SF

    Hillsboro Mixed-Use Redevelopment Opportunity

    9637 Old State Route 21, Hillsboro, MO 63050

    Versatile 6-acre property with highway frontage and redevelopment potential.

    • Prime highway frontage on 6 acres offering outstanding visibility and accessibility.
    • Versatile property with four buildings suitable for redevelopment or continued hospitality use.
    • Existing infrastructure includes a restaurant, four hotel rooms, a three‑bedroom residence, and a large outbuilding.
    • Many upgrades completed in 2018.
    • Much of the existing equipment remains in good condition.
    Updated: Feb 16
    View details
    Hillsboro Retail with Highway Frontage
    $299,000
    0.27 Acres

    Hillsboro Retail with Highway Frontage

    10550 Business 21, Hillsboro, MO 63050

    Retail property in Hillsboro with highway frontage and recent updates.

    • High‑traffic corner location with highway frontage
    • New roof installed in 2022
    • New furnace and AC
    • Updated flooring and fresh paint in 2019
    • Three offices (or two offices and a conference room)
    Updated: Apr 29, 2025
    View details
    Hillsboro Retail Property for Sale
    $2,200,000
    9,641 SF

    Hillsboro Retail Property for Sale

    9,641 SF retail property available in Hillsboro, Missouri.

    10333 Business 21, Hillsboro, MO
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    Commercial Property Near City Hall
    $426,900
    2,772 SF

    Commercial Property Near City Hall

    Updated commercial property with large lot near government buildings.

    114 Main St, Hillsboro, MO 63050
    View details
    Based on your search, we've compiled 82 Potential Opportunities for your consideration. Besides 4 Active listings in Hillsboro, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 70 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    De Soto Retail Business Opportunity
    $850,000
    15,500 SF

    De Soto Retail Business Opportunity

    Own a business and a piece of history!

    400 S Main Street, De Soto, MO 63020
    View details
    Commercial Lots in Prime Location
    $623,400
    1.79 Acres

    Commercial Lots in Prime Location

    1.79 acres near Highway 30, suitable for various businesses.

    0 Cedric Station, Cedar Hill, MO 63016
    View details
    Under Construction Dollar General Market
    $2,055,000
    1.88 Acres

    Under Construction Dollar General Market

    New 15-year NNN lease Dollar General Market for sale.

    8440 Local Hillsboro Road, Cedar Hill, MO
    View details
    De Soto Commercial Property
    $115,000

    De Soto Commercial Property

    Commercial property for sale in De Soto, Missouri.

    112 W Kelley Street, De Soto, MO 63020
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Hillsboro Land Near City Hall
    $426,900
    2,772 SF

    Hillsboro Land Near City Hall

    Versatile half-acre lot in prime Hillsboro location.

    114 Main Street, Hillsboro, MO 63050
    View details
    Commercial Land on Corner Lot
    $350,000
    0.98 Acres

    Commercial Land on Corner Lot

    Corner lot with high visibility near highways in Hillsboro, MO.

    10865 Business 21, Hillsboro, MO 63050
    View details
    Commercial Lot on Highway 30
    $84,900
    1.56 Acres

    Commercial Lot on Highway 30

    1.54 acre commercial lot with highway visibility.

    7095 Old Hwy 30, Cedar Hill, MO 63016
    View details
    Commercial Land on Truman Boulevard
    $250,000

    Commercial Land on Truman Boulevard

    0.32 acre commercial land with high visibility.

    520 S Truman Boulevard, Festus, MO 63028
    View details

    Explore Off-Market Properties in Hillsboro, MO

    Consider similar Off-Market properties in Hillsboro, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    10308 Business 21

    10308 Business 21

    RETAIL STORES (PERSONAL SERVICES) • 1,254 SF
    Value Estimation by Request
    10308 Business 21, Hillsboro, MO 63050-3583
    View details
    10510 Business 21

    10510 Business 21

    AUTO REPAIR, GARAGE • 2,946 SF
    Value Estimation by Request
    10510 Business 21, Hillsboro, MO 63050-5901
    View details
    10410 Business 21

    10410 Business 21

    NURSERY, GREENHOUSE, FLORIST • 1,427 SF
    Value Estimation by Request
    10410 Business 21, Hillsboro, MO 63050-5709
    View details
    3812 State Rd Z Z

    3812 State Rd Z Z

    CONVENIENCE STORE (W/FUEL PUMP) • 6,188 SF
    Value Estimation by Request
    3812 State Rd Z Z, Hillsboro, MO 63050-3715
    View details
    10575 Business 21

    10575 Business 21

    RETAIL STORES (PERSONAL SERVICES) • 2,049 SF
    Value Estimation by Request
    10575 Business 21, Hillsboro, MO 63050-5904
    View details
    10544 Business 21

    10544 Business 21

    CONVENIENCE STORE (W/FUEL PUMP) • 0.45 Acres
    Value Estimation by Request
    10544 Business 21, Hillsboro, MO 63050-5902
    View details
    3824 State Rd Z Z

    3824 State Rd Z Z

    AUTO REPAIR, GARAGE • 5,500 SF
    Value Estimation
    $615,000
    3824 State Rd Z Z, Hillsboro, MO 63050-3715
    View details
    10610 Business 21

    10610 Business 21

    RETAIL STORES (PERSONAL SERVICES) • 3,674 SF
    Value Estimation by Request
    10610 Business 21, Hillsboro, MO 63050-5039
    View details
    929 Peach Tree Plz Dr

    929 Peach Tree Plz Dr

    RETAIL STORES (PERSONAL SERVICES) • 1.06 Acres
    Value Estimation
    $500,000
    929 Peach Tree Plz Dr, Hillsboro, MO 63050-5115
    View details
    144 7th St

    144 7th St

    RETAIL STORES (PERSONAL SERVICES) • 4,500 SF
    Value Estimation by Request
    144 7th St, Hillsboro, MO 63050-5042
    View details
    10290 Business 21

    10290 Business 21

    AUTO REPAIR, GARAGE • 3,699 SF
    Value Estimation by Request
    10290 Business 21, Hillsboro, MO 63050-3596
    View details
    10255 Business 21

    10255 Business 21

    RESTAURANT • 2,128 SF
    Value Estimation by Request
    10255 Business 21, Hillsboro, MO 63050-5707
    View details
    10281 Business 21

    10281 Business 21

    RETAIL STORES (PERSONAL SERVICES) • 3,456 SF
    Value Estimation by Request
    10281 Business 21, Hillsboro, MO 63050-5707
    View details
    4 Hickory Rdg Rd

    4 Hickory Rdg Rd

    RETAIL STORES (PERSONAL SERVICES) • 9,169 SF
    Value Estimation
    $845,000
    4 Hickory Rdg Rd, Hillsboro, MO 63050-5100
    View details
    8144 Old State Rte 21

    8144 Old State Rte 21

    AUTO REPAIR, GARAGE • 588 SF
    Value Estimation by Request
    8144 Old State Rte 21, Hillsboro, MO 63050-1704
    View details
    10640 Business 21

    10640 Business 21

    RETAIL STORES (PERSONAL SERVICES) • 12,200 SF
    Value Estimation
    $750,000
    10640 Business 21, Hillsboro, MO 63050-5039
    View details
    8015 Gamble Rd

    8015 Gamble Rd

    AUTO REPAIR, GARAGE • 1,716 SF
    Value Estimation by Request
    8015 Gamble Rd, Hillsboro, MO 63050-1800
    View details
    9132 State Rd Bb

    9132 State Rd Bb

    AUTO REPAIR, GARAGE • 3,646 SF
    Value Estimation by Request
    9132 State Rd Bb, Hillsboro, MO 63050-2303
    View details
    1 Leon Hall Pkwy

    1 Leon Hall Pkwy

    RETAIL STORES (PERSONAL SERVICES) • 2,316 SF
    Value Estimation by Request
    1 Leon Hall Pkwy, Hillsboro, MO 63050-3418
    View details
    6227 State Rd Y Y

    6227 State Rd Y Y

    AUTO REPAIR, GARAGE • 792 SF
    Value Estimation by Request
    6227 State Rd Y Y, Hillsboro, MO 63050-4513
    View details

    Hillsboro, MO Retail Properties & Spaces Investment Opportunities Market Analysis

    Explore 74 retail properties & spaces for sale in Hillsboro, MO, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 18,503 square feet of properties for sale, with an estimated market value of $3,076,900.

    Sale prices for stores in Hillsboro, MO start at $426,900, averaging $1,025,633, and reaching up to $2,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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