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    Florence, CO Retail Properties & Spaces for Sale

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    Denver, CO Colorado Springs, CO Pueblo, CO
    12 results
    Historic Building in Florence's Golden Block
    $349,500
    0.08 Acres

    Historic Building in Florence's Golden Block

    111 W Main Street, Florence, CO 81226

    Refurbished commercial building in Florence's thriving downtown district.

    • Prime "Golden Block" location in Florence's Antique Capital of America with high foot traffic and excellent visibility.
    • Optional turnkey business: existing successful retail business available for purchase.
    • Refurbished historic building featuring exposed brick walls and updated flooring.
    • Flexible zoning suitable for retail, gallery, boutique, or other commercial ventures.
    • Practical amenities including a private garage, additional storage, rear staff parking, and a private restroom with utility sink.
    Updated: Mar 13
    View details
    Mixed-Use Investment in Historic Downtown
    $675,000
    0.08 Acres

    Mixed-Use Investment in Historic Downtown

    122 W Main Street, Florence, CO 81226

    Live-work investment opportunity in Florence's Historic Downtown on Main Street.

    • Live‑work investment opportunity in Historic Downtown Florence.
    • Includes business space (previously a wine bar) and a 2‑bedroom residential unit.
    • Prime Main Street location close to amenities.
    • Ample free customer parking.
    • Proximity to outdoor activities: rafting, hiking, biking, rock climbing, fishing, kayaking.
    Updated: Oct 31, 2025
    View details
    Historic Downtown Florence Live-Work Space
    $675,000
    0.08 Acres

    Historic Downtown Florence Live-Work Space

    Live-work investment opportunity in historic downtown Florence, Colorado.

    122 W Main Street, Florence, CO 81226
    View details
    Main Street Mixed-Use Opportunity
    $550,000
    0.22 Acres

    Main Street Mixed-Use Opportunity

    Mixed-use property with restaurant, retail, and apartment potential.

    102-106 E Main Street, Florence, CO 81226
    View details
    Mixed-Use Property on Main Street
    $550,000
    15,519 SF

    Mixed-Use Property on Main Street

    Mixed-use property with restaurant, retail, and apartment potential.

    102-106 Main Street, Florence, CO 81226
    View details
    Historic Mixed-Use Building with Loft
    $480,000
    2,850 SF

    Historic Mixed-Use Building with Loft

    Main Street investment opportunity with business spaces and luxury loft.

    119 Main Street, Florence, CO 81226
    View details
    Historic Downtown Florence Mixed-Use Building
    $480,000
    0.08 Acres

    Historic Downtown Florence Mixed-Use Building

    Mixed-use building with business spaces and luxury loft in Florence.

    119 W Main Street, Florence, CO 81226
    View details
    Commercial Land with Income Streams
    $285,000

    Commercial Land with Income Streams

    4.7 acres with U-Haul dealership and propane refill operation.

    280 Moore Drive, Florence, CO 81226
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    Main Street Mixed-Use Opportunity
    $550,000
    13,519 SF

    Main Street Mixed-Use Opportunity

    Mixed-use property with restaurant, retail, and apartment potential.

    102-106 Main Street, Florence, CO 81226
    View details
    Florence Mixed-Use Commercial Building
    $724,000
    5,300 SF

    Florence Mixed-Use Commercial Building

    Remodeled commercial space with living quarters in booming Florence, Colorado.

    122 W Main Street, Florence, CO 81226
    View details
    Versatile Commercial Space in Florence
    $300,000
    5,600 SF

    Versatile Commercial Space in Florence

    5,600 sq ft commercial space with flexible zoning.

    117 S Petroleum Ave, Florence, CO 81226
    View details
    Mixed-Use Property on Main Street
    $550,000

    Mixed-Use Property on Main Street

    Mixed-use property with restaurant, retail, and apartment opportunities.

    E Main Street, Florence, CO 81226
    View details
    Based on your search, we've compiled 73 Potential Opportunities for your consideration. Besides 12 Active listings in Florence, CO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 53 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Historic Penrose Commercial Building
    $1,250,000
    8,660 SF

    Historic Penrose Commercial Building

    Unique commercial building with historic significance and development potential.

    708 Fremont St, Penrose, CO 81240
    View details
    Canon City Commercial Land Opportunity
    $1,750,000
    2,880 SF

    Canon City Commercial Land Opportunity

    1.4 acre commercial land with highway access in Canon City.

    3275 E US Hwy 50, Canon City, CO 81212
    View details
    Versatile Commercial Building with Kitchen
    $320,000
    0.73 Acres

    Versatile Commercial Building with Kitchen

    Well-maintained commercial property with a fully equipped kitchen area.

    880 Marilyn Dr, Penrose, CO
    View details
    Retail Space Near Highway 50
    $6,800,000
    1,800 SF

    Retail Space Near Highway 50

    Retail space with high ceilings and significant upgrades.

    121-127 Justice Center Rd, Canon City, CO
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Canon City Commercially Zoned Land
    $198,900
    4.78 Acres

    Canon City Commercially Zoned Land

    4.78 acre commercially zoned land near US Highway 50.

    County Road 123, Canon City, CO 81212
    View details
    Commercial Corner Lot on Highway
    $425,000
    0.56 Acres

    Commercial Corner Lot on Highway

    Prime commercial land with high traffic and utilities available.

    101 Steinmeier Avenue, Canon City, CO 81212
    View details
    Commercial Corner Lot on Highway
    $425,000
    0.56 Acres

    Commercial Corner Lot on Highway

    Commercially zoned corner lot with high traffic and utilities.

    101 Steinmeier Avenue, Canon City, CO 81212
    View details
    Penrose Land with Highway Access
    $199,000
    2.72 Acres

    Penrose Land with Highway Access

    2.72 acres with shop, utilities, and highway access.

    1390 K Street, Penrose, CO 81240
    View details

    Explore Off-Market Properties in Florence, CO

    Consider similar Off-Market properties in Florence, CO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    114 Main St

    114 Main St

    RETAIL STORES (PERSONAL SERVICES) • 2,000 SF
    Value Estimation by Request
    114 Main St, Florence, CO 81226-1529
    View details
    117 Petroleum Ave

    117 Petroleum Ave

    RETAIL STORES (PERSONAL SERVICES) • 2,800 SF
    Value Estimation by Request
    117 Petroleum Ave, Florence, CO 81226-1540
    View details
    502 Main St

    502 Main St

    DRIVE-THRU RESTAURANT, FAST FOOD • 3,817 SF
    Value Estimation
    $1,105,000
    502 Main St, Florence, CO 81226-1250
    View details
    107 Main St

    107 Main St

    RETAIL STORES (PERSONAL SERVICES) • 1,380 SF
    Value Estimation by Request
    107 Main St, Florence, CO 81226-1528
    View details
    727 Main St

    727 Main St

    RESTAURANT • 3,580 SF
    Value Estimation by Request
    727 Main St, Florence, CO 81226-1642
    View details
    107 Main St

    107 Main St

    RETAIL STORES (PERSONAL SERVICES) • 7,920 SF
    Value Estimation by Request
    107 Main St, Florence, CO 81226-1421
    View details
    850 Main St

    850 Main St

    SHOPPING CENTER, STRIP CENTER • 9,409 SF
    Value Estimation
    $995,000
    850 Main St, Florence, CO 81226-1645
    View details
    115 Main St

    115 Main St

    RETAIL STORES (PERSONAL SERVICES) • 19,320 SF
    Value Estimation
    $530,000
    115 Main St, Florence, CO 81226-1569
    View details
    102 Maple St

    102 Maple St

    RETAIL STORES (PERSONAL SERVICES) • 2,604 SF
    Value Estimation by Request
    102 Maple St, Florence, CO 81226-1428
    View details
    111 Main St

    111 Main St

    RETAIL STORES (PERSONAL SERVICES) • 2,151 SF
    Value Estimation by Request
    111 Main St, Florence, CO 81226-1421
    View details
    223 Main St

    223 Main St

    RESTAURANT • 3,042 SF
    Value Estimation by Request
    223 Main St, Florence, CO 81226-1423
    View details
    921 Main St

    921 Main St

    CONVENIENCE STORE • 4,312 SF
    Value Estimation
    $2,655,000
    921 Main St, Florence, CO 81226-1646
    View details

    Florence, CO Retail Properties & Spaces Investment Opportunities Market Analysis

    Explore 65 retail properties & spaces for sale in Florence, CO, showcased through 12 active listings on our real estate platform. These investment opportunities span a total of 42,788 square feet of properties for sale, with an estimated market value of $2,604,000.

    Sale prices for stores in Florence, CO start at $300,000, averaging $520,800, and reaching up to $724,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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