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Florence, CO Mixed-use Properties for Sale

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11 results
Mixed-Use Investment in Historic Downtown
$675,000
0.08 Acres

Mixed-Use Investment in Historic Downtown

122 W Main Street, Florence, CO 81226

Live-work investment opportunity in Florence's Historic Downtown on Main Street.

  • Live‑work investment opportunity in Historic Downtown Florence.
  • Includes business space (previously a wine bar) and a 2‑bedroom residential unit.
  • Prime Main Street location close to amenities.
  • Ample free customer parking.
  • Proximity to outdoor activities: rafting, hiking, biking, rock climbing, fishing, kayaking.
Updated: Oct 31, 2025
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Historic Downtown Florence Live-Work Space
$675,000
0.08 Acres

Historic Downtown Florence Live-Work Space

122 W Main Street, Florence, CO 81226

Live-work investment opportunity in historic downtown Florence, Colorado.

  • Live‑work investment opportunity in Historic Downtown Florence.
  • Includes commercial space (previously a wine bar) and a 2‑bedroom residential unit.
  • Prime location on Main Street, close to amenities.
  • Ample free customer parking.
  • Near outdoor recreation: Arkansas River, rafting, hiking, biking, rock climbing.
Updated: Oct 31, 2025
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Main Street Mixed-Use Opportunity
$550,000
0.22 Acres

Main Street Mixed-Use Opportunity

Mixed-use property with restaurant, retail, and apartment potential.

102-106 E Main Street, Florence, CO 81226
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Mixed-Use Property on Main Street
$550,000
15,519 SF

Mixed-Use Property on Main Street

Mixed-use property with restaurant, retail, and apartment potential.

102-106 Main Street, Florence, CO 81226
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Mixed-Use Building in Florence, CO
$300,000

Mixed-Use Building in Florence, CO

Classic mixed-use building with remodeling potential on Main Street.

108 W Main Street, Florence, CO 81226
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Historic Mixed-Use Building with Loft
$480,000
2,850 SF

Historic Mixed-Use Building with Loft

Main Street investment opportunity with business spaces and luxury loft.

119 Main Street, Florence, CO 81226
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Mixed-Use Building in Florence, CO
$300,000
0.17 Acres

Mixed-Use Building in Florence, CO

Classic mixed-use building with remodeling potential on Main Street.

108 W Main Street, Florence, CO 81226
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Historic Downtown Florence Mixed-Use Building
$480,000
0.08 Acres

Historic Downtown Florence Mixed-Use Building

Mixed-use building with business spaces and luxury loft in Florence.

119 W Main Street, Florence, CO 81226
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Main Street Mixed-Use Opportunity
$550,000
13,519 SF

Main Street Mixed-Use Opportunity

Mixed-use property with restaurant, retail, and apartment potential.

102-106 Main Street, Florence, CO 81226
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Historic Mixed-Use Property in Florence
$480,000
2,850 SF

Historic Mixed-Use Property in Florence

Mixed-use property with business spaces and luxury loft in Florence.

119 W Main Street, Florence, CO 81226
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Mixed-Use Property on Main Street
$550,000

Mixed-Use Property on Main Street

Mixed-use property with restaurant, retail, and apartment opportunities.

E Main Street, Florence, CO 81226
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Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 11 Active listings in Florence, CO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 3 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Versatile Commercial Space with Extra Land
$1,090,000
2.42 Acres

Versatile Commercial Space with Extra Land

39,974 sq ft commercial space with retail, office, warehouse.

1630 E Main Street, Canon City, CO 81212
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Restored Residence with Income Potential
$750,000
0.60 Acres

Restored Residence with Income Potential

Renovated residence with business potential and income-generating apartment.

2950 E Main Street, Canon City, CO 81212
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Historic Victor Mixed-Use Investment
$445,000
6,216 SF

Historic Victor Mixed-Use Investment

Mixed-use property in revitalizing mountain town, potential for co-living.

400 Victor Avenue, Victor, CO 80860
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Historic Mixed-Use Building in Victor
$225,000

Historic Mixed-Use Building in Victor

Mixed-use building with storefront and apartment in revitalizing downtown.

308 Victor Avenue, Victor, CO 80860
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Land in Historic Cripple Creek
Contact for pricing
0.14 Acres

Land in Historic Cripple Creek

Land in historic mining town, close to amenities.

Cripple Creek, CO 80813
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Pueblo Blvd Frontage Land Parcel
$1,000,000
4.53 Acres

Pueblo Blvd Frontage Land Parcel

Prime commercial land parcel with Pueblo Blvd frontage.

3530 W 11th St, Pueblo, CO 81003
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Pueblo Blvd Frontage Land Parcel
$1,000,000
2.55 Acres

Pueblo Blvd Frontage Land Parcel

Prime 2.55-acre commercial land parcel with Pueblo Blvd frontage.

4100 W 11th St, Pueblo, CO 81003
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Pueblo, CO Land For Sale
$2,970,000
20.00 Acres

Pueblo, CO Land For Sale

20 acre land parcel available in Pueblo, Colorado.

No Site Address, Pueblo, CO 81008
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Explore Off-Market Properties in Florence, CO

Consider similar Off-Market properties in Florence, CO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

Main St

Main St

Mixed-use properties • 0.22 Acres
Value Estimation by Request
Main St, Florence, CO 81226
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119 Main St

119 Main St

Mixed-use properties • 0.08 Acres
Value Estimation by Request
119 Main St, Florence, CO 81226
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305 Main St

305 Main St

Mixed-use properties
Value Estimation by Request
305 Main St, Florence, CO 81226
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Florence, CO Mixed-Use Properties Investment Opportunities Market Analysis

Explore 14 mixed-use properties for sale in Florence, CO, showcased through 11 active listings on our real estate platform. These investment opportunities span a total of 48,090 square feet of properties for sale, with an estimated market value of $4,060,000.

Sale prices for multi use buildings in Florence, CO start at $300,000, averaging $507,500, and reaching up to $675,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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