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    Port St Lucie, FL Retail Properties & Spaces for Lease

    18 results
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    Freestanding Building on US Highway
    $26 SF/Yr
    46,609 SF

    Freestanding Building on US Highway

    10244 S Us Highway 1, Port St Lucie, FL 34952

    General Commercial zoning ideal for retail, medical, or restaurant.

    • High‑traffic location on US Hwy 1 with 35,500 AADT and 187' frontage.
    • General Commercial zoning suitable for retail, medical, restaurant, or professional use.
    • Ideal sub‑lease option with two separate entrances.
    • Existing electronic and media infrastructure wiring throughout.
    • Modular interior wall system allows for easy reconfiguration.
    Updated: Nov 16, 2025
    View details
    Freestanding Building on US Highway
    $26 SF/Yr

    Freestanding Building on US Highway

    10244 S Us Highway 1, Port St Lucie, FL 34952

    Versatile commercial space ideal for retail, medical, or restaurant use.

    • Prime location on US Hwy 1 with high traffic (AADT 35,500) in the Port St. Lucie retail corridor, near Port St. Lucie Hospital.
    • Versatile General Commercial zoning suitable for retail, medical, restaurant, or professional use.
    • Potential for sub‑lease with separate entrances for two tenants.
    • Existing infrastructure and wiring to support electronic and media systems.
    • Flexible interior with modular walls and a large open area for easy reconfiguration.
    View details
    Port St. Lucie Retail Center
    $23 SF/Yr

    Port St. Lucie Retail Center

    Retail strip center with high-traffic exposure on US-1 Highway.

    7630 S Us Highway 1, Port St Lucie, FL 34952
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    Outparcels Available For Lease
    Contact for pricing

    Outparcels Available For Lease

    Outparcel opportunities in Lowe’s anchored shopping center.

    SW Village Pkwy, Port St Lucie, FL 34953
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    Retail Space in St Lucie
    Contact for pricing
    4,529 SF

    Retail Space in St Lucie

    Retail space available in a busy shopping center.

    1315-1367 St Lucie Blvd W, Port St Lucie, FL
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    Retail Unit in PSL Centre
    Contact for pricing
    950 SF

    Retail Unit in PSL Centre

    950 SF commercial unit with US 1 visibility.

    8479-8521 S Us Highway 1, Port St Lucie, FL 34952
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    Retail Space in Renovated Center
    Contact for pricing
    1,256 SF

    Retail Space in Renovated Center

    Retail space available in Publix-anchored shopping center.

    3203-3245 SW Port St Lucie Blvd, Port St Lucie, FL 34953
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    Retail Space in Growing Community
    Contact for pricing
    14,400 SF

    Retail Space in Growing Community

    Retail space near new developments in Tradition, Port St. Lucie.

    10340 SW Discovery Way, Port St Lucie, FL 34987
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    Retail Space in St. Lucie
    Contact for pricing
    4,529 SF

    Retail Space in St. Lucie

    Retail property with high traffic and strong demographics.

    1449-1497 St Lucie Blvd W, Port St Lucie, FL
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    Retail Space For Lease
    $24 SF/Yr
    1,600 SF

    Retail Space For Lease

    Retail space available for lease in Port St. Lucie.

    10921-10941 Us Highway 1, Port St Lucie, FL 34952
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    Retail Space in Publix Anchored Center
    Contact for pricing
    1,283 SF

    Retail Space in Publix Anchored Center

    Retail space available in a Publix and Ace anchored center.

    7576-7594 Us Highway 1, Port St Lucie, FL 34952
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    Commercial Plaza in Growing Tradition
    $40 SF/Yr
    2,122 SF

    Commercial Plaza in Growing Tradition

    Future commercial plaza in rapidly growing Tradition area.

    11650 SW Village Pkwy, Port St Lucie, FL 34987
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    Retail Space in Publix-Anchored Center
    $30 SF/Yr
    1,700 SF

    Retail Space in Publix-Anchored Center

    Retail space available in a busy, renovated shopping center.

    9020-9164 Us Highway 1, Port St Lucie, FL 34952
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    Anchored Retail Center For Lease
    Contact for pricing

    Anchored Retail Center For Lease

    Retail space available in Publix and Ace Hardware anchored center.

    7576 Us Highway 1, Port St Lucie, FL 34952
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    Retail Space in Renovated Center
    Contact for pricing
    900 SF

    Retail Space in Renovated Center

    Retail space available in a recently renovated shopping center.

    3253-3261 SW Prt St, Port St Lucie, FL
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    Based on your search, we've compiled 37 Potential Opportunities for your consideration. Besides 18 Active listings in Port St Lucie, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 15 Properties for Sales.

    Explore Retail properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Port Saint Lucie Retail Opportunity
    $60,000
    15,894 SF

    Port Saint Lucie Retail Opportunity

    Retail space available in Port Saint Lucie, Florida.

    7991 S Us Highway 1, Fort Pierce, FL 34952
    View details
    Cashmere Corners Medical Office
    Contact for pricing
    85,708 SF

    Cashmere Corners Medical Office

    Port St. Lucie Medical Office Building

    870 St. Lucie Blvd, Port St. Lucie, FL 34986
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    Shoppes at St. Lucie West Retail Space
    Contact for pricing
    88,342 SF

    Shoppes at St. Lucie West Retail Space

    Prime Port St. Lucie retail space available. Multiple suites, flexible sizes.

    1333 St. Lucie Blvd, Port St. Lucie, FL 34986
    View details
    Retail Space For Rent
    Contact for pricing
    3,582 SF

    Retail Space For Rent

    Retail space available for rent in Fort Pierce, Florida.

    4901 S Us Highway 1, Fort Pierce, FL 34946
    View details

    Explore Similar Spaces for Sale in Port St Lucie, FL

    Consider Similar Space for Sale. We found 15 Spaces in Nearby Locations matching your search parameters.

    Port St Lucie Showroom/Warehouse
    $235,000
    0.02 Acres

    Port St Lucie Showroom/Warehouse

    Turnkey showroom/warehouse in established Port St. Lucie commercial district.

    1459 SE Village Green Dr, Port St Lucie, FL 34952
    View details
    Profitable Jamaican Restaurant Opportunity
    $125,000

    Profitable Jamaican Restaurant Opportunity

    Turn-key Jamaican restaurant for sale in Port St. Lucie.

    3453 SW Darwin Blvd, Port St Lucie, FL 34953
    View details
    US-1 Frontage Commercial Lot
    $999,888
    0.79 Acres

    US-1 Frontage Commercial Lot

    Commercial lot with high traffic frontage on US-1.

    10720 S Us Highway 1, Port St Lucie, FL 34952
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    Turn-Key Commercial Condo in St. Lucie
    $1,300,000

    Turn-Key Commercial Condo in St. Lucie

    4500+ SF condo in St. Lucie West's retail corridor.

    266 NW Peacock Blvd, Port St Lucie, FL 34986
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    Artisan Ice Cream Business Opportunity
    $125,000

    Artisan Ice Cream Business Opportunity

    Turnkey artisan ice cream and dessert business in Port St. Lucie.

    Port St Lucie, FL 34985
    View details
    Prime Location Retail/Gas Station Opportunity
    $1,500,000

    Prime Location Retail/Gas Station Opportunity

    High-visibility property near major retailers, suitable for various commercial uses.

    00 Prima Vista Blvd, Port St Lucie, FL 34952
    View details
    St. Lucie West Commercial Condominium
    $1,300,000

    St. Lucie West Commercial Condominium

    Turn-key commercial condominium in St. Lucie West.

    266 NW Peacock Blvd, Port St Lucie, FL 34986
    View details
    Established Carpet and Supplies Business
    $39,000

    Established Carpet and Supplies Business

    Well-established carpet and supplies business with inventory and equipment included.

    1496 SE Village Green Dr, Port St Lucie, FL 34952
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    Retail Space in Port St. Lucie
    Contact for pricing

    Retail Space in Port St. Lucie

    Retail space available in a fast-growing Port St. Lucie location.

    7121 S Us Hwy 1 Hwy 7151, Port St Lucie, FL 34950
    View details

    Port St Lucie, FL Retail properties & Spaces Leasing Opportunities Market Analysis

    Explore Retail properties & Spaces leasing options in Port St Lucie, FL with 33 listings featured on our commercial real estate exchange. The current inventory includes 12,061,119,278 square feet of properties with an estimated lease value of $147 SF/Yr.

    Estimated lease rates for Retail properties & Spaces in Port St Lucie, FL begin at $12 SF/Yr, with an average of $24 SF/Yr and extend to $40 SF/Yr.
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    Browse Retail properties & Spaces for Lease Near Port St Lucie, FL

    Popular Searches in Port St Lucie, FL

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    Most Searched ZIP Codes in Port St Lucie, FL

    • 34952
    • 34953
    • 34983
    • 34984
    • 34987

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