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    Columbia, SC Office Units for Lease

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    Cayce, SC West Columbia, SC Lexington, SC
    147 results
    Turnkey Medical Office Suites
    $20 SF/Yr
    3,742 SF

    Turnkey Medical Office Suites

    4100 N. Main Street, Columbia, SC 29203

    Turnkey suites with exam rooms and plumbing, recently renovated common areas, designed for efficient medical operations.

    • 1987‑built medical office with turnkey suites featuring exam rooms with plumbing
    • Suite 101: ±2,484 SF available 8/1/26
    • Suite 200: ±1,226 SF with reception, 3 exam rooms (with plumbing), 1 private office, and restroom
    • Suite 201: ±2,516 SF with large reception/waiting area, 6 exam rooms (with plumbing), 2 private offices, IT/storage rooms, and restroom
    • Major renovations in 2019 included new roof, building façade, and common area upgrades
    Updated: Jun 2
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    Columbia Flex Space For Lease
    $12 SF/Yr
    12,550 SF

    Columbia Flex Space For Lease

    901 Brookwood Drive, Columbia, SC 29201

    Flex space available for lease in Columbia, South Carolina.

    • ±12,550 SF Flex Space Available
    • Recently renovated office and warehouse
    • Benefit from 21' clear height
    • Ample parking
    • One drive‑in door and one dock high door
    Updated: May 19
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    Office Space in Vista District
    $23 SF/Yr
    6,782 SF

    Office Space in Vista District

    Office spaces for lease in Columbia's popular Vista district.

    500 Taylor Street, Columbia, SC 29201
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    Premier Office Tower with Capitol Views
    $40 SF/Yr
    2,289 SF

    Premier Office Tower with Capitol Views

    Office space in Columbia's premier tower with integrated parking.

    1221 Main Street, Columbia, SC 29201
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    Office Space For Rent
    $20 SF/Yr
    15,000 SF

    Office Space For Rent

    Office suites available in Columbia, between Downtown and Forest Acres.

    3321 Forest Drive, Columbia, SC 29204
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    Prime Office Space on Devine
    $23 SF/Yr
    12,200 SF

    Prime Office Space on Devine

    Office space for lease in the Devine Street District.

    2422 Devine Street, Columbia, SC 29205
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    Warehouse with Secured Yard
    $12 SF/Yr
    5,000 SF

    Warehouse with Secured Yard

    5,000 SF warehouse with office and secured yard.

    125 North Shorecrest Drive, Columbia, SC 29209
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    Devine Street Office Space Available
    $18 SF/Yr
    10,500 SF

    Devine Street Office Space Available

    Office space for lease on highly trafficked Devine Street.

    2442 Devine St., Columbia, SC 29205
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    Columbia Office Space For Lease
    $17 SF/Yr
    7,072 SF

    Columbia Office Space For Lease

    High-quality office space in a well-located Columbia area.

    8910 Two Notch Road, Columbia, SC 29223
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    Professional Office Space For Rent
    $18 SF/Yr
    2,500 SF

    Professional Office Space For Rent

    2,500 SF office space in Irmo/Columbia corridor.

    1492 Lake Murray Blvd, Columbia, SC
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    Class A Office Sublease Opportunity
    $15 SF/Yr
    289,129 SF

    Class A Office Sublease Opportunity

    Suburban campus setting, Class A office space for sublease.

    1200 Colonial Life Blvd., Columbia, SC 29210
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    Class A Office Space Sublease
    $19 SF/Yr
    298,926 SF

    Class A Office Space Sublease

    Move-in ready Class A office space in the heart of CBD.

    1301 Gervais Street, Columbia, SC 29201
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    Downtown Columbia Office Space Available
    $30 SF/Yr
    170,000 SF

    Downtown Columbia Office Space Available

    Office space for lease in Columbia's Central Business District.

    1230 Main Street, Columbia, SC 29201
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    Riverfront Office and Retail Space
    $18 SF/Yr
    30,000 SF

    Riverfront Office and Retail Space

    Class A office and retail in Canalside development near Downtown.

    325 Taylor St, Columbia, SC 29201
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    Downtown Office Space for Rent
    $18 SF/Yr
    138,909 SF

    Downtown Office Space for Rent

    Office space in Columbia's Central Business District, near retail.

    1501 Main Street, Columbia, SC 29201
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    Office Suites For Lease
    $18 SF/Yr
    49,138 SF

    Office Suites For Lease

    Office suites available for lease with recent common area upgrades.

    107 Westpark Blvd., Columbia, SC 29210
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    Office/Retail Space Near Riverbanks Zoo
    $2,000/Mo
    1,600 SF

    Office/Retail Space Near Riverbanks Zoo

    1,600 SF office/retail space with frontage on Interstate 126.

    208 Candi Ln, Columbia, SC
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    Columbia Office Space For Rent
    $12 SF/Yr
    18,463 SF

    Columbia Office Space For Rent

    Premier office complex with amenities and interstate visibility in Columbia.

    400 Arbor Lake Drive, Columbia, SC 29223
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    Forest Acres Office Space Available
    $18 SF/Yr
    19,266 SF

    Forest Acres Office Space Available

    Office space for lease in Forest Acres with recent renovations.

    4408 Forest Drive, Columbia, SC 29206
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    Columbia Office/Medical Space For Lease
    $21 SF/Yr
    20,822 SF

    Columbia Office/Medical Space For Lease

    Office and medical space available for lease in Columbia, SC.

    120 & 122 Highland Center Dr., Columbia, SC 29203
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    Downtown Columbia Office Space Available
    $1,200/Mo
    1,300 SF

    Downtown Columbia Office Space Available

    Prime office spaces in the heart of downtown Columbia.

    1720 Main St, Columbia, SC
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    Retail/Office Space in Forest Acres
    Contact for pricing
    1,464 SF

    Retail/Office Space in Forest Acres

    Retail/office space in a visible, accessible, and affordable location.

    3304-3312 Forest Drive, Columbia, SC 29204
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    Premium Commercial Office Space
    $22 SF/Yr
    684 SF

    Premium Commercial Office Space

    Professional office space in a bustling business district.

    3200 Devine St, Columbia, SC
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    Office/Flex Center in Columbia
    $15 SF/Yr
    9,208 SF

    Office/Flex Center in Columbia

    47,810 SF Office/Flex Center with interstate access.

    7499 Parklane Road, Columbia, SC 29223
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    Columbia, SC Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in Columbia, SC with 147 listings featured on our commercial real estate exchange. The current inventory includes 1,551,636 square feet of properties with an estimated lease value of $1,970 /Mo.

    Estimated lease rates for Office Units in Columbia, SC begin at $3 SF/Yr, with an average of $20 SF/Yr and extend to $99 SF/Yr.
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