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    Charleston, SC Office Units for Lease

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    Columbia, SC Spartanburg, SC North Charleston, SC
    86 results
    Charleston Historic District Office Space
    $22 SF/Yr
    4,204 SF

    Charleston Historic District Office Space

    2 Cumberland St, Charleston, SC 29401

    Renovated office suites with harbor views in historic Charleston.

    • Rare views of Charleston Harbor, Ravenel Bridge, US Customs House, and USS Yorktown.
    • Newly renovated suites with modern finishes ready for immediate occupancy.
    • Located in the historic district of Charleston's peninsula.
    • Open floorplans provide functional versatility.
    • Suites available on the 2nd and 3rd floors, each with 4,204 RSF.
    Updated: Mar 6
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    Downtown Charleston Freestanding Building
    $29 SF/Yr
    14,518 SF

    Downtown Charleston Freestanding Building

    276 East Bay Street, Charleston, SC 29401

    Freestanding building in historic downtown Charleston with on-site parking.

    • Prime location in historic downtown Charleston, walking distance to restaurants and shopping.
    • Rare on‑site parking with 38 spaces.
    • High traffic volume (28,300 VPD) and excellent walkability (83%).
    • Flexible space options: lease entire building or subdivide by floor.
    • Close proximity to Union Pier development and future College of Charleston Business School.
    Updated: Nov 21, 2025
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    Wappoo Creek Office Space Available
    $20 SF/Yr
    2,944 SF

    Wappoo Creek Office Space Available

    Office space for lease in a convenient Charleston location.

    125 Wappoo Creek Dr, Charleston, SC 29412
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    Daniel Island Office Space Available
    $32 SF/Yr
    3,975 SF

    Daniel Island Office Space Available

    Second-floor office suite in Daniel Island's Town Center.

    115 Riverlanding Dr, Charleston, SC
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    James Island Office Space Available
    $20 SF/Yr
    2,200 SF

    James Island Office Space Available

    Office space for lease in a convenient Charleston location.

    125 Wappoo Creek Dr, Charleston, SC 29412
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    Charleston Historic District Office Space
    $22 SF/Yr
    16,816 SF

    Charleston Historic District Office Space

    Renovated office suites with harbor views in Charleston's historic district.

    2 Cumberland St, Charleston, SC 29401
    View details
    Renovated Office Space on King
    $23 SF/Yr
    2,631 SF

    Renovated Office Space on King

    Renovated office space in Charleston's 'Dine & Design' district.

    579 King Street, Charleston, SC 29403
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    Class A Office Space Available
    $22 SF/Yr
    20,028 SF

    Class A Office Space Available

    Class A office suite for lease in growing Daniel Island/Cainhoy.

    1951 Clements Ferry, Charleston, SC 29492
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    Historic Mixed-Use Building on King
    $35 SF/Yr
    10,673 SF

    Historic Mixed-Use Building on King

    Renovated mixed-use building in Charleston's Upper King Street corridor.

    438 King St, Charleston, SC 29403
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    Move-in Ready Office/Retail Space
    $44 SF/Yr

    Move-in Ready Office/Retail Space

    Office or retail space with on-site parking on Shem Creek.

    103 Church Street, Charleston, SC 29464
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    Savannah Highway Retail/Office Space
    $30 SF/Yr
    4,168 SF

    Savannah Highway Retail/Office Space

    Freestanding building with excellent visibility and ample parking.

    422 Savannah Hwy, Charleston, SC
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    Class A Office Space Available
    $49 SF/Yr
    3,851 SF

    Class A Office Space Available

    Up to 3,851 SF of fully up-fitted Class A office space.

    651 Meeting St, Charleston, SC
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    West Ashley Medical Office Space
    $22 SF/Yr
    3,000 SF

    West Ashley Medical Office Space

    3,000 SF office space in the heart of West Ashley.

    1027 Physicians Dr, Charleston, SC
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    Downtown Charleston Office Space
    $29 SF/Yr

    Downtown Charleston Office Space

    Office space for rent in Charleston's growing Upper Peninsula.

    11 Isabella St Suite A, Charleston, SC 29403
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    Savannah Highway Retail/Office Building
    $16 SF/Yr
    2,800 SF

    Savannah Highway Retail/Office Building

    Free-standing 2,800 SF retail or office building for lease.

    2413 Savannah Hwy, Charleston, SC
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    Charleston Peninsula Office Space
    $36 SF/Yr
    7,390 SF

    Charleston Peninsula Office Space

    Cool office space in pioneering mixed-use redevelopment on Charleston Peninsula.

    1501 King Street Extension, Charleston, SC 29405
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    Renovated Office/Retail Building on East Bay
    $30 SF/Yr
    3,789 SF

    Renovated Office/Retail Building on East Bay

    Modern, flexible office/retail space in prime downtown location.

    341 East Bay St, Charleston, SC
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    Office Space on Jessen Lane
    $20 SF/Yr
    1,500 SF

    Office Space on Jessen Lane

    Highly visible office space in a rapidly growing commercial corridor.

    405 Jessen Ln, Charleston, SC
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    Downtown Charleston Office Space Available
    $25 SF/Yr
    2,040 SF

    Downtown Charleston Office Space Available

    Office suites for lease in downtown Charleston's office district.

    180 Meeting St, Charleston, SC
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    Adaptive Reuse Retail/Office Space
    $39 SF/Yr
    6,285 SF

    Adaptive Reuse Retail/Office Space

    Historic warehouse architecture with modern design in Charleston's NoMo.

    1505 King St, Charleston, SC
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    Upper King Street Office Space
    $34 SF/Yr
    3,204 SF

    Upper King Street Office Space

    Office space for rent in Charleston's Upper King District.

    463 King Street, Charleston, SC 29403
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    Charleston Office Space For Lease
    Contact for pricing
    2,576 SF

    Charleston Office Space For Lease

    Office space available for lease in Charleston, South Carolina.

    711 Meeting St, Charleston, SC 29403
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    Daniel Island Office/Medical Opportunity
    Contact for pricing
    928 SF

    Daniel Island Office/Medical Opportunity

    Office/Medical space in Publix-anchored Daniel Island shopping center.

    162 Seven Farms Dr, Charleston, SC
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    Downtown Charleston Office Space
    $29 SF/Yr
    1,650 SF

    Downtown Charleston Office Space

    Office space for rent in Charleston's growing Upper Peninsula.

    11 Isabella St Suite A, Charleston, SC 29403
    View details

    Charleston, SC Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in Charleston, SC with 86 listings featured on our commercial real estate exchange. The current inventory includes 7,136,304,120 square feet of properties with an estimated lease value of $942 /Mo.

    Estimated lease rates for Office Units in Charleston, SC begin at $12 SF/Yr, with an average of $31 SF/Yr and extend to $84 SF/Yr.
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    Popular Searches in Charleston, SC

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    Most Searched ZIP Codes in Charleston, SC

    • 29401
    • 29407
    • 29403
    • 29492
    • 29405
    • 29406
    • 29412
    • 29418
    • 29464

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